RESUMEN
Preliminary screening of antiviral AIDS drugs has been carried out using three different in vitro assay systems. Among 96 samples of different origin tested, two were shown to inhibit the growth of HIV in vitro. One of the positive samples (plant origin) has hopeful signs, as the ranges of effective doses are wider than those of most of positive samples which had been found by us.
Asunto(s)
Síndrome de Inmunodeficiencia Adquirida/tratamiento farmacológico , Fármacos Anti-VIH/farmacología , Evaluación Preclínica de Medicamentos/métodosRESUMEN
Preliminary screening of antiviral AIDS drugs has been carried out using three different in vitro assay systems. Among 138 samples tested, two were found to inhibit the growth of HIV in vitro. Neither of the positive samples has hopeful signs, as the ranges of effective doses of the samples are very narrow.
Asunto(s)
Fármacos Anti-VIH/farmacología , VIH-1/efectos de los fármacos , Evaluación Preclínica de Medicamentos/métodos , Farmacorresistencia Microbiana , Pruebas de Sensibilidad Microbiana/métodosRESUMEN
Preliminary screening of antiviral AIDS drugs has been carried out using three different in vitro assay systems. Among 246 samples of different origin tested, six were shown to inhibit the growth of HIV in vitro. Two of the positive samples have hopeful signs, as the ranges of effective doses are wider than those of most of positive samples which had been found by us.
Asunto(s)
Fármacos Anti-VIH/farmacología , VIH-1/efectos de los fármacos , Evaluación Preclínica de Medicamentos/métodos , Farmacorresistencia Microbiana , Pruebas de Sensibilidad Microbiana/métodosRESUMEN
Preliminary screening of antiviral AIDS drugs has been carried out using three different in vitro assay systems. Among 191 samples tested, seven were found to inhibit the growth of HIV in vitro. Four of seven have hopeful signs, as the ranges of effective doses of the samples are wide.
Asunto(s)
Antivirales/farmacología , VIH/efectos de los fármacos , Células Cultivadas , Relación Dosis-Respuesta a Droga , Evaluación Preclínica de Medicamentos , Farmacorresistencia Microbiana , Humanos , Pruebas de Sensibilidad MicrobianaRESUMEN
Preliminary screening for antiviral AIDS drugs has been carried out using three different in vitro assay systems. Among 106 samples tested, five were found to inhibit the growth of HIV in vitro. Two of five have a hopeful sign, as the range of effective doses of the samples is wide.
Asunto(s)
Antivirales/farmacología , VIH-1/efectos de los fármacos , Evaluación Preclínica de Medicamentos , Pruebas de Sensibilidad Microbiana/métodosRESUMEN
Preliminary screening for antiviral AIDS drugs was carried out using three different in vitro assay systems. Among 104 samples tested, six were found to inhibit the growth of HIV in vitro. Four of six were acidic polysaccharides of sea weed origin and one was a well-known anti HIV chemical whose anti-HIV activity has not been reported.