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Praxis (Bern 1994) ; 97(5): 235-9; quiz 240-1, 2008 Mar 05.
Artículo en Alemán | MEDLINE | ID: mdl-18548805

RESUMEN

A 55-year-old male patient was hospitalized with severe nausea, vomiting and icterus. Laboratory testing showed hepatocellular damage. After exhaustive testing, the exclusion diagnosis of a toxic hepatitis was reached. There was a strong temporal correlation with the ingestion of Hong Hua 29, a preparation from Traditional Chinese Medicine (TCM). This medication had been started twelve days prior to the first appearance of symptoms. The existing drug regimen included gabapentin (Neurontin), esomeprazole (Nexium) and prednisone (Prednison Streuli) for the therapy of an acute sensory and motor neuropathy of unknown aetiology. After cessation of Hong Hua 29, gabapentin and esomeprazole, transaminase levels started to declined and normalized within three months. According to the Swissmedic criteria of imputability, a causal correlation between the observed symptoms and the administration of Hong Hua 29 is possible.


Asunto(s)
Enfermedad Hepática Inducida por Sustancias y Drogas/etiología , Medicamentos Herbarios Chinos/toxicidad , Laca/toxicidad , Neuritis/inducido químicamente , Neuritis/tratamiento farmacológico , Enfermedades Profesionales/inducido químicamente , Biopsia , Enfermedad Hepática Inducida por Sustancias y Drogas/patología , Colestasis Intrahepática/inducido químicamente , Colestasis Intrahepática/diagnóstico , Colestasis Intrahepática/patología , Quimioterapia Combinada , Medicamentos Herbarios Chinos/uso terapéutico , Humanos , Hígado/patología , Pruebas de Función Hepática , Masculino , Persona de Mediana Edad , Neuritis/diagnóstico , Neuritis/patología , Enfermedades Profesionales/diagnóstico , Enfermedades Profesionales/patología
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