1.
Biosci Biotechnol Biochem
; 76(1): 209-11, 2012.
Artículo
en Inglés
| MEDLINE
| ID: mdl-22232270
RESUMEN
Octopamine receptors are attractive insecticide targets. To screen compounds acting at octopamine receptors simply and rapidly, we constructed a chemiluminescent reporter gene assay system that detects secreted placental alkaline phosphatase transcriptionally regulated by the cAMP response element for a silkworm octopamine receptor. This system proved useful in high-throughput screening to develop octopamine receptor-specific insecticides.