1.
Chem Commun (Camb)
; 57(82): 10763-10766, 2021 Oct 14.
Artículo
en Inglés
| MEDLINE
| ID: mdl-34585682
RESUMEN
Cu(II)-mediated C-H sulphenylation or selenylation of Trp indole by a derivative of cysteine or selenocysteine enables access to the tryptathionine unit or its selenium congener. The mechanism of these protocols, which allow macrocyclization of Trp-containing peptides, has been studied.
Asunto(s)
Cobre/química , Péptidos Cíclicos/síntesis química , Selenio/química , Triptófano/química , Secuencia de Aminoácidos , Catálisis , Ciclización , Disulfuros/química , Indoles/química , Lactamas/química , Oxidación-Reducción , Fenotiazinas/química , Pirrolidinonas/química , Tripsina/química
2.
Chem Commun (Camb)
; 51(38): 8020-2, 2015 May 11.
Artículo
en Inglés
| MEDLINE
| ID: mdl-25778790
RESUMEN
Spatiotemporal control of peptide nanofibre growth was achieved by photocleavage of a DNA-conjugated ß-sheet forming peptide that is linked through a photoresponsive amino acid residue. Peptide nanofibres were selectively formed by photocleaving the conjugate on a complementary DNA-immobilised glass substrate.