RESUMEN
Three new water-soluble constituents [ficuscarpanoside B (1), (7E,9Z)-dihydrophaseic acid 3-O-beta-D-glucopyranoside (4) and ficuscarpanic acid (6)] and the natural product 2,2'-dihydroxyl ether (7) have been isolated, together with three known compounds [(7S,8R)-syringoylglycerol (2), (7S,8R)-syringoylglycerol-7-O-beta-D-glucopyranoside (3) and icariside D2 (5)] from the aerial roots of Ficus microcarpa. Identification of their structures was achieved by 1D and 2D NMR experiments, including 1H-1H COSY, NOESY, HMQC and HMBC methods and FAB mass spectral data.
Asunto(s)
Compuestos Bicíclicos Heterocíclicos con Puentes/química , Ácidos Dicarboxílicos/química , Ácidos Grasos Insaturados/química , Ficus/química , Glucósidos/química , Glicósidos/química , Reguladores del Crecimiento de las Plantas/química , Raíces de Plantas/química , Plantas Medicinales/química , Compuestos Bicíclicos Heterocíclicos con Puentes/aislamiento & purificación , Cromatografía , Ácidos Dicarboxílicos/aislamiento & purificación , Ácidos Grasos Insaturados/aislamiento & purificación , Glucósidos/aislamiento & purificación , Glicósidos/aislamiento & purificación , Estructura Molecular , Reguladores del Crecimiento de las Plantas/aislamiento & purificación , Espectrofotometría , TaiwánRESUMEN
Eight new triterpenoid saponins, kudinosides I-P along with three known saponins were isolated from the leaves of Ilex kudincha. The aglycone moiety of kudinosides I-K was determined as a new triterpene (kudinolic acid), a fore-genin for the lactonic triterpene. The structures of all saponins were established on the basis of spectroscopic and chemical evidence. The biogenesis of the triterpene with lactonic moiety was briefly discussed.
Asunto(s)
Medicamentos Herbarios Chinos/química , Plantas Medicinales/química , Saponinas/química , Saponinas/aislamiento & purificación , Triterpenos/química , Triterpenos/aislamiento & purificación , Cromatografía Líquida de Alta Presión , Espectroscopía de Resonancia Magnética , Espectrometría de Masas , Estructura Molecular , Hojas de la Planta/química , Espectrofotometría Infrarroja , Estereoisomerismo , Relación Estructura-ActividadRESUMEN
Three new saponins, named kudinosides A, B and C, were isolated from the leaves of Ilex kudincha. On the basis of spectroscopic analysis and chemical transformation their structures were elucidated as 3-O-beta-D-glucopyranosyl-(1-->3)-[alpha-L-rhamnopyranosyl- (1-->2)]-alpha-L-arabinopyranosyl-beta-kudinlactone, 3-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->3)-alpha-L- arabinopyranosyl-beta-kudinlactone and 3-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->3)-[alpha-L -rhamnopyranosyl-(1-->2)]-alpha-L-arabinopyranosyl-beta-kudinla c tone.
Asunto(s)
Plantas Medicinales , Saponinas/química , Triterpenos/química , Conformación de Carbohidratos , Secuencia de Carbohidratos , Espectroscopía de Resonancia Magnética , Medicina Tradicional China , Datos de Secuencia Molecular , Estructura Molecular , Rotación Óptica , Hojas de la Planta , Saponinas/aislamiento & purificación , Triterpenos/aislamiento & purificaciónRESUMEN
Two new triterpenes, alpha- and beta-kudinlactone, and six new triterpenoid glycosides, kudinosides D-G, I and J, were isolated from the leaves of Ilex kudincha. Their structures have been elucidated by spectroscopic and chemical means.