RESUMEN
Lipid peroxidation and antioxidant system were studied at hospital admission, on postoperative day 1, 3 weeks and half a year after surgery in 86 patients with different stages of laryngeal cancer. A correlation is stated between lipid peroxidation disturbances and the defects in the protective antioxidant system. Low-frequency laser irradiation of autoblood produced a clinically beneficial effect and stabilized biochemically the relations between lipid peroxidation and antioxidant systems.
Asunto(s)
Antioxidantes/metabolismo , Neoplasias Laríngeas/sangre , Oxidantes/metabolismo , Adulto , Antioxidantes/efectos de la radiación , Sangre/efectos de la radiación , Transfusión de Sangre Autóloga , Terapia Combinada , Circulación Extracorporea , Humanos , Neoplasias Laríngeas/patología , Neoplasias Laríngeas/terapia , Terapia por Láser , Peroxidación de Lípido/efectos de la radiación , Persona de Mediana Edad , Estadificación de Neoplasias , Oxidantes/efectos de la radiación , Periodo Posoperatorio , Factores de TiempoRESUMEN
The authors elaborated the equipment and technique of endolaryngeal laser surgery under indirect laryngoscopy in conditions of local anesthesia as well as phototherapy of the larynx with coherent and noncoherent monochromatic light in the postoperative period. Therapy was conducted and assessment of its efficacy was made in 93 patients with benign tumours, cysts of the larynx and laryngopharynx, cicatricial membranes of the middle regions of the larynx. The efficacy of the given method was assessed on the basis of long-term laryngoscopic studies, stroboscopy and acoustic measurements of the voice. Indications and contraindications to the mentioned therapy have been specified.