RESUMEN
Congenital mesoblastic nephroma is a rare pediatric renal tumor and has been reported in patients presenting with palpable abdominal mass, arterial hypertension, hematuria, polyuria, or hypercalcemia. Here we present the case of a 1-month-old neonate with suspected parathyroid hormone (PTH)-related peptide (PTH-rp)-mediated severe hypercalcemia revealing congenital mesoblastic nephroma. Preoperatively, hypercalcemia was corrected with hydration, furosemide, pamidronate, and low-calcium infant formula. Unilateral nephrectomy led to the resolution of hypercalcemia, transient hyperparathyroidism, and transient vitamin D and mineral supplementation. We conclude that congenital mesoblastic nephroma can secrete PTH-rp that can cause severe hypercalcemia.
Asunto(s)
Hipercalcemia/congénito , Neoplasias Renales/congénito , Nefroma Mesoblástico/congénito , Calcio/sangre , Femenino , Alimentos Fortificados , Furosemida/uso terapéutico , Humanos , Hipercalcemia/etiología , Hipercalcemia/terapia , Hipertensión , Fórmulas Infantiles , Recién Nacido , Neoplasias Renales/complicaciones , Neoplasias Renales/cirugía , Nefrectomía , Nefroma Mesoblástico/complicaciones , Nefroma Mesoblástico/cirugía , Pamidronato/uso terapéutico , Resultado del TratamientoRESUMEN
We report a case of tuberculous dactylitis--spina ventosa--in a 5 year-old girl from a French upper class family. Being today an unusual affection, the diagnosis of spina ventosa can be missed. Symptoms and means of diagnosis are reviewed.