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Int J Clin Pharmacol Biopharm ; 17(8): 329-333, 1979 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-489200

RESUMEN

This is an article reviewing the literature and our experience to date (six months) in the treatment of cancer using whole body hyperthermia in the first 60 patients. WBHT is an effective method of treating cancer. Patients were treated for a total of eight hours, 180 degrees F for two hours. WBHT was induced by means of two high-flow water filled blankets. Toxicity included fatigue, nausea, diarrhea and first degree burns. There was no evidence of visceral damage. There were no mortalities during the procedure. Objective responses were 50%, subjective responses were 65%. The literature demonstrates and our study confirms that under closely monitored conditions, WBHT is a feasible, safe and active anti-cancer therapy. WBHT may be safely used as an adjunct to other active cancer therapies including X-ray therapy and chemotherapy.


Asunto(s)
Hipertermia Inducida , Animales , Antineoplásicos/farmacología , Reparación del ADN , ADN de Neoplasias/metabolismo , Ratones , Trasplante de Neoplasias , Neoplasias Experimentales/diagnóstico por imagen , Neoplasias Experimentales/inmunología , Neoplasias Experimentales/metabolismo , Neoplasias Experimentales/terapia , Oxígeno/farmacología , Consumo de Oxígeno/efectos de los fármacos , ARN Neoplásico/metabolismo , Radiografía , Sarcoma 180/terapia , Trasplante Homólogo
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