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1.
Microb Pathog ; 149: 104504, 2020 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-32950636

RESUMEN

In the absence of vaccines and antiviral drugs available to prevent and treat COVID-19, it becomes imperative to find or use all those products with the potential to fight this virus. This article is an attempt to propose ways to prevent, treat and control the COVID-19 virus, using a product based on plant extracts with the potential to reduce the symptoms caused by the SARS-CoV-2 virus. Nasoil® counts as one of its main components, Asclepias curassavica extracts, and in the present study it has been shown that it is an effective adjuvant in the treatment of Covid-19, increasing the respiratory capacity of the patients (SpO2> 90%) and reducing the symptoms from the first application, improving the patients around the fifth to the eighth application. At a preventive level, the individuals in this study who have applied it (400 individuals) only a 3.15% of these presented symptoms, disappearing when increasing the weekly applications.


Asunto(s)
Antivirales/administración & dosificación , Tratamiento Farmacológico de COVID-19 , SARS-CoV-2/efectos de los fármacos , Administración Intranasal , Adulto , Anciano , Asclepias/química , COVID-19/fisiopatología , COVID-19/virología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Extractos Vegetales/administración & dosificación
2.
Microb Pathog ; 125: 96-107, 2018 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-30195644

RESUMEN

Cancer and infectious diseases are the preeminent causes of human morbidities and mortalities worldwide. At present, chemotherapy, radiotherapy, immunotherapy, and gene therapy are considered as predominant options in order to treat cancer. But these therapies provide inadequate consequences by affecting both the normal and tumor cells. On the other hand, tuberculosis (TB), and HIV (human immunodeficiency virus) infections are significant threats, causing over a million mortalities each year. The extensive applications of antibiotics have caused the microbes to acquire resistance to the existing antibiotics. With the emerging dilemma of drug resistant microbes, it has become imperative to identify novel therapeutic agents from natural sources as emphatic alternative approach. Over the past few decades, venoms derived from several reptiles, amphibians, and arthropods including snakes, scorpions, frogs, spiders, honey bees, wasps, beetles, caterpillars, ants, centipedes, and sponges have been identified as efficient therapeutics. Venoms constitute plethora of bioactive components, particularly peptides, enzymes, and other chemical entities, which exhibit a large array of anticancer and anti-pathogenic activities. This review highlights the panorama of bioactive components of animal venoms divulging the anticancer, anti-tubercular, and anti-HIV activities. In a nutshell, this context discloses the decisive role of animal venoms as alternative natural resources to combat these deadly diseases of 21st century, and propounding the plausible development of new therapeutic drugs in the present era.


Asunto(s)
Síndrome de Inmunodeficiencia Adquirida/terapia , Productos Biológicos/uso terapéutico , Terapia Biológica/métodos , Neoplasias/terapia , Tuberculosis/terapia , Ponzoñas/uso terapéutico , Animales , Productos Biológicos/farmacología , Humanos , Ponzoñas/farmacología
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