[Chronic systemic toxicity of oral photochemotherapy using 8-methoxypsoralen and UVA]. / Untersuchungen zur chronisch-systemischen Toxizität einer oralen Photochemotherapie mit 8-Methoxypsoralen und UVA.

The purpose of the study conducted was to clarify the question of chronic, systemic toxicity from PUVA therapy. Five groups of patients, classified according to length of treatment were examined with respect to 43 laboratory parameters. The results indicated that PUVA had no chronic toxic influence on the liver, kidneys, bone marrow, metabolism, or immune response.

[The radiophosphorus (32P)-test in precanceroses and malignant tumors of the skin]. / Radiophosphor (32P)-Test bei Präkanzerosen und malignen Tumoren der Haut

In 21 patients with a variety of skin tumors (squamous cell carcinomas, malignant melanomas, basal cell epitheliomas and mycosis fungoides) or pre-cancerous lesions (Bowen's disease, actinic keratosis, junctional nevus cell nevus) the radioactive phosphorus uptake test demonstrates a significantly increased concentration of P32 in those tumors. There were no false negative tests. The possibility of differentiation of malignant melanoma from benign nevus cell nevus and the early recognition of cutaneous metastases is described. Furthermore recurrence of previously irradiated or excised basal cell epitheliomas can be detected without a biopsy. No hematological side-effects were observed.