Asunto(s)
Plaquetas , Epidermólisis Ampollosa Distrófica/terapia , Sangre Fetal/citología , Terapia por Luz de Baja Intensidad , Enfermedades de la Boca/terapia , Mucosa Bucal/efectos de la radiación , Adolescente , Adulto , Niño , Terapia Combinada , Epidermólisis Ampollosa Distrófica/diagnóstico , Femenino , Geles , Humanos , Masculino , Enfermedades de la Boca/diagnóstico , Mucosa Bucal/patología , Proyectos Piloto , Estudios Prospectivos , Inducción de Remisión , Factores de Tiempo , Resultado del Tratamiento , Adulto JovenAsunto(s)
Enfermedades Maxilomandibulares/etiología , Neoplasias de la Boca/complicaciones , Osteonecrosis/etiología , Osteonecrosis de los Maxilares Asociada a Difosfonatos/etiología , Osteonecrosis de los Maxilares Asociada a Difosfonatos/prevención & control , Atención Dental para Enfermos Crónicos , Humanos , Oxigenoterapia Hiperbárica , Neoplasias de la Boca/tratamiento farmacológico , Neoplasias de la Boca/radioterapia , Osteonecrosis/prevención & control , Osteorradionecrosis/etiología , Osteorradionecrosis/prevención & control , Factores de RiesgoRESUMEN
BACKGROUND: Burning mouth syndrome (BMS) is a chronic, intraoral burning sensation seen mainly in middle-aged and post-menopausal females, without identifiable oral lesions or abnormal laboratory findings, but often associated with psychogenic disorders such as depression. The latter can have a range of causes, including hormonal. OBJECTIVE: Since there may be connections between BMS, psychogenic changes, hormonal changes and taste abnormalities, we have examined aspects of taste and thyroid function. PATIENTS AND METHODS: We selected 50 patients with BMS (study group) and 50 healthy subjects (control group) and analysed their ability to taste bitter, acid and spicy substances and analysed their thyroid function and Undertook thyroid echography. RESULTS: Taste sensation was normal in all controls. However, 30 of the patients with BMS reported ageusia for bitter taste and 2 had ageusia for acid. The use of pepper sauce (Tabasco) (spicy substance) produced a strong burning to the tongue in 28 patients of the BMS group but only in 10 controls. No control patients showed abnormality of thyroid function or echograpic abnormality. Five patients in the BMS group had biochemical evidence of hypothyroidism, 4 patients had raised levels of thyroid auto-antibodies and, of the 41 remaining BMS patients, most (34) had thyroid echographic changes indicative of nodularity. CONCLUSIONS: Hypothyroidism may be responsible for a negative influence on taste and consequent increase in trigeminal sensorial sensation (tactile, thermal and painful sensation).
Asunto(s)
Síndrome de Boca Ardiente/complicaciones , Hipotiroidismo/complicaciones , Trastornos del Gusto/etiología , Capsicum , Estudios de Casos y Controles , Ácido Cítrico , Femenino , Humanos , Hipotiroidismo/diagnóstico , Persona de Mediana Edad , Preparaciones de Plantas , Taninos , Trastornos del Gusto/complicaciones , Trastornos del Gusto/diagnóstico , Pruebas de Función de la TiroidesRESUMEN
BackgroundBurning mouth syndrome (BMS) is a chronic, intraoral burning sensation seen mainly in middle-aged and post-menopausal females, without identifiable oral lesions or abnormal laboratory findings, but often associated with psychogenic disorders such as depression. The latter can have a range of causes, including hormonal. ObjectiveSince there may be connections between BMS, psychogenic changes, hormonal changes and taste abnormalities , we have examined aspects of taste and thyroid function.. Patients and methodsWe selected 50 patients with BMS (study group) and 50 healthy subjects (control group) and analysed their ability to taste bitter, acid and spicy substances and analysed their thyroid function and Undertook thyroid echography. ResultsTaste sensation was normal in all controls. However, 30 of the patients with BMS reported ageusia for bitter taste and 2 had ageusia for acid. The use of pepper sauce ( Tabasco®) (spicy substance) produced a strong burning to the tongue in 28 patients of the BMS group but only in 10 controls. No control patients showed abnormality of thyroid function or echograpic abnormality.Five patients in the BMS group had biochemical evidence of hypothyroidism, 4 patients had raised levels of thyroid auto-antibodies and, of the 41 remaining BMS patients, most (34) had thyroid echographic changes indicative of nodularity. ConclusionsHypothyroidism may be responsible for a negative influence on taste and consequent increase in trigeminal sensorial sensation (tactile, thermal and painful sensation)
Asunto(s)
Femenino , Persona de Mediana Edad , Humanos , Síndrome de Boca Ardiente/complicaciones , Hipotiroidismo/complicaciones , Trastornos del Gusto/etiología , Capsicum , Estudios de Casos y Controles , Hipotiroidismo/diagnóstico , Preparaciones de Plantas , Taninos , Trastornos del Gusto/complicaciones , Trastornos del Gusto/diagnóstico , Pruebas de Función de la Tiroides , Ácido CítricoRESUMEN
BACKGROUND: Recurrent aphthous stomatitis, or RAS, is a common oral disorder of uncertain etiopathogenesis for which symptomatic therapy only is available. This article reviews the current data on the etiopathogenesis, diagnosis and management of RAS in a primary care setting. METHODS: The authors reviewed publications on Medline from 1995 through 2000, the period since the last major reviews were published. RESULTS: RAS may have an immunogenetic background owing to cross-reactivity with Streptococcus sanguis or heat shock protein. Predisposing factors seen in a minority include haematinic (iron, folate or vitamin B12) deficiency, stress, food allergies and HIV infection. While topical corticosteroids remain the mainstay for therapy, a number of other immunomodulatory modalities now are available. CONCLUSIONS: There is still no conclusive evidence relevant to the etiopathogenesis of RAS, and therefore therapy can attempt only to suppress symptoms rather than to address the basic issues of susceptibility and prevention. CLINICAL IMPLICATIONS: In the majority of patients, symptomatic relief of RAS can be achieved with topical corticosteroids alone, with other immunomodulatory topical agents or by combination therapy.