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1.
Biomolecules ; 11(4)2021 04 08.
Artículo en Inglés | MEDLINE | ID: mdl-33917892

RESUMEN

The industrial processing amazon fruits, like tucuma, generates a large amount of coproducts with large nutritional potential. Thus, this work obtained the oily extract of the tucuma almonds coproducts by green extraction using palm oil by the ultrasound method and then microencapsulated by atomization and verification of its antioxidant activity. Thermogravimetric techniques, infrared spectroscopy, scanning electron microscopy, moisture content, water activity were applied to characterize the microparticles. Total carotenoids were determined by UV spectroscopy and antioxidant activity was measured by 2,2'-azino-di-(3-ethylbenzthiazoline sulfonic acid and co-oxidation in the system ß-carotene/linoleic acid. The oily extract and microparticle had total carotenoid contents of 3.305 mg/100 g ± 0.01 and 2.559 mg/100 g ± 0.01, respectively. The antioxidant activity assessed through the 2,2'-azino-di-(3-ethylbenzthiazoline sulfonic acid value was 584.75 µM/trolox ± 0.01 (oily extract) and 537.12 µM/trolox ± 0.01 (microparticle) were determined. In the system ß-carotene/linoleic acid showed oxidation of 49.9% ± 1.8 lipophilic extract and 43.3% ± 2.3 microparticle. The results showed that the oily extract of the tucuma almond coproduct can be used as a carotenoid-rich source and microencapsuled with possible application for functional foods production.


Asunto(s)
Antioxidantes/química , Arecaceae/química , Extractos Vegetales/química , Sonicación/métodos , Arecaceae/metabolismo , Rastreo Diferencial de Calorimetría , Carotenoides/análisis , Frutas/química , Frutas/metabolismo , Ácido Linoleico/química , Tamaño de la Partícula , Espectroscopía Infrarroja por Transformada de Fourier , Secado por Pulverización , Termogravimetría , beta Caroteno/química
2.
PLoS One ; 15(1): e0226979, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-31952077

RESUMEN

Libidibia ferrea (juca) is a plant belonging to the Fabaceae (Leguminosae) family, whose antioxidant activity has been widely described in the literature. We evaluated this parameter of Aqueous ethanol extract (AE), ethyl acetate (ACO), chloroform (CLO) and hexane (HEX) extracts of L. ferrea. We then tested the most active extract for its toxicity and ability to inhibit migratory activity in the ACP02 gastric adenocarcinoma cell line in vitro. The AE and ACO extracts both had antioxidant activity, the AE extract showing greater potential. This may reflect that both extracts contained phenolic compounds. Although AE extract showed no cytotoxic, mutagenic or genotoxic effect, it altered cell morphology and migration activity. Analysis of apoptosis/necrosis indicated that this parameter does not appear to account for the apparent ability of AE to inhibit cancer cell migration. We speculate that the morphological changes in AE-treated cells could be due to cytoskeleton alterations related to the presence of myo-inositol in AE extract. Together, our results demonstrate this extract of L. ferrea can act as an exogenous antioxidant and might prove useful in efforts to fight secondary tumors.


Asunto(s)
Antineoplásicos/aislamiento & purificación , Antioxidantes/aislamiento & purificación , Caesalpinia/química , Movimiento Celular/efectos de los fármacos , Extractos Vegetales/farmacología , Neoplasias Gástricas/tratamiento farmacológico , Adenocarcinoma/tratamiento farmacológico , Antineoplásicos/farmacología , Antioxidantes/farmacología , Apoptosis/efectos de los fármacos , Línea Celular Tumoral , Etanol , Humanos , Solventes/química , Neoplasias Gástricas/patología
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