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1.
J Pediatr Orthop ; 38(5): e278-e284, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29521937

RESUMEN

BACKGROUND: For large scoliosis, 2 strategies to maximize correction include intraoperative traction and/or anterior release. It is unclear which patients will benefit the most form either approach. The purpose of our study is to compare the radiographic, perioperative clinical outcomes, and health-related quality of life (HRQoL) outcomes of 2 approaches when used in severe neuromuscular scoliosis in the setting of cerebral palsy (CP). METHODS: In total, 23 patients with minimum 2-year follow-up, major curves ≥100 degrees, and in whom treatment included posterior spinal fusion were evaluated. Eighteen were treated with posterior spinal fusion with intraoperative traction and 5 with anterior/posterior spinal fusion (APSF). The baseline characteristics, perioperative outcomes, and preoperative and 2-year follow-up data for HRQoL and radiographic measures were compared. RESULTS: The groups had similar age, sex, nutritional and seizure status, GMFCS level, and change in CPCHILD scores. The groups had similar curve magnitude (120 vs. 105 degrees, P=0.330) and flexibility (28% vs. 40%, P=0.090), but the APSF group had less pelvic obliquity (POB) (24 vs. 42 degrees, P=0.009). There were similar postoperative major curves (37 vs. 40 degrees, P=0.350), but greater correction in POB (33.5 vs. 14 degrees of correction, P=0.007) in the traction group. The APSF group had longer anesthesia times (669 vs. 415 min, P=0.005), but similar hospital stays, intensive care unit and days intubated, estimated blood loss, cell saver, and red blood cells used. Although the APSF group had twice the rate of complications (22% vs. 40%) during the first 90 days postoperatively, this did not reach statistical significance. CONCLUSIONS: Both intraoperative traction and anterior surgery were used to aid correction in severe CP scoliosis. Anterior surgery did not offer superior correction or better HRQoL, and was associated with increased operative times, whereas intraoperative traction was associated with greater correction of POB. Intraoperative traction may be a viable alternative to an anterior release in severe CP scoliosis. LEVEL OF EVIDENCE: Level II.


Asunto(s)
Parálisis Cerebral/complicaciones , Calidad de Vida , Escoliosis , Fusión Vertebral/métodos , Adolescente , Adulto , Parálisis Cerebral/psicología , Niño , Femenino , Estudios de Seguimiento , Humanos , Masculino , Periodo Posoperatorio , Radiografía/métodos , Radiografía/estadística & datos numéricos , Estudios Retrospectivos , Escoliosis/diagnóstico , Escoliosis/etiología , Escoliosis/cirugía , Vértebras Torácicas/diagnóstico por imagen , Vértebras Torácicas/cirugía , Tracción/métodos , Resultado del Tratamiento
2.
World Neurosurg ; 102: 13-17, 2017 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-28279772

RESUMEN

OBJECTIVE: To evaluate the association of perioperative hemoglobin A1c (HbA1c) level in patients with diabetes with the incidence of infection after anterior cervical discectomy and fusion requiring operative intervention, in addition to determining if a threshold level of HbA1c above which the risk of infection increases significantly exists. METHODS: A national administrative database was queried for patients who underwent primary anterior cervical discectomy and fusion with diabetes who had a perioperative HbA1c level recorded within 3 months of surgery. These patients were stratified based on their HbA1c level in 0.5-mg/dL increments from <5.49 mg/dL to >11.5 mg/dL. The incidence of infection requiring operative intervention within 1 year was then identified using Current Procedural Terminology and International Classification of Diseases, Ninth Revision codes. A receiver operating characteristic (ROC) analysis was performed to determine a threshold value of the HbA1c level. RESULTS: A total of 3341 patients with a perioperative HbA1c level were included. The rate of deep infection requiring irrigation and debridement postoperatively stratified by HbA1c level ranged from a low of 1.5% to a high of 6.4% and was significantly correlated with increasing HbA1c levels (P = 0.005). The results of ROC analysis determined that the inflection point of the ROC curve corresponded to an HbA1c level higher than 7.5 mg/dL (P = 0.022; area under the curve, 0.67; specificity, 68%; sensitivity, 46%). CONCLUSIONS: The risk of deep postoperative infection in patients with diabetes mellitus increases as the perioperative HbA1c level increases. ROC analysis determined that a perioperative HbA1c level higher than 7.5 mg/dL could serve as a threshold for a significantly increased risk of infection.


Asunto(s)
Discectomía/efectos adversos , Hemoglobina Glucada/metabolismo , Fusión Vertebral/efectos adversos , Infección de la Herida Quirúrgica/etiología , Glucemia , Estudios de Cohortes , Diabetes Mellitus/cirugía , Femenino , Humanos , Incidencia , Masculino , Programas Nacionales de Salud/estadística & datos numéricos , Curva ROC , Análisis de Regresión , Infección de la Herida Quirúrgica/epidemiología , Estados Unidos
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