1.
Dokl Biochem Biophys
; 488(1): 320-323, 2019 Sep.
Artículo
en Inglés
| MEDLINE
| ID: mdl-31768851
RESUMEN
It was shown for the first time that pentaamino acid derivative of fullerene C60 (potassium salt of fullerenylpenta-N-dihydroxytyrosine) affects three targets of type 2 diabetes mellitus. It competitively inhibits the enzymes aldose reductase and sorbitol dehydrogenase and also has an antiglycation effect on bovine serum albumin. The inhibition constants for these enzymes were calculated.