[Intrahypothalamic connections of the lateral hypothalamus]. / Vnutrigipotalamicheskie sviazi lateral'nogo gipotalamusa.

Using the axon degeneration method by R. Fink and L. Heimer, organization of intrathalamic connections between various areas of the lateral hypothalamus have been studied after unisided electrolitic lesion. At any location of the injury foci, similar patterns are observed in ipsilateral distribution of degenerating fibers along the whole lateral preoptico-hypothalamic area. The most massive degeneration is observed in the zone where the medial forebrain bundle (MFB) fibers run. The degenerating fibers spread forward--into the septal area, and backward--into the mesencephalic part of the brain. The rostral and caudal parts of the lateral hypothalamus, taking part in formation of the MFB collateralies towards the thalamus, are connected with various thalamic nuclei. Massive preterminal degeneration in the perifornical zone and single argerophile granules in the medial hypothalamus convincingly demonstrate an important role of the intermediate zone for connections of its medial and lateral parts with each other. The conclusion that the intrahypothalamic connections of the lateral hypothalamus are realized within the MFB system supports the modern notion on a close connection of the lateral hypothalamus with the system of longitudinal diffuse bundles of fibers of the medial anterocerebral pathway that run through it.

[Intrahypothalamic connections of the rostral and caudal portions of the hypothalamus (retrograde axonal horseradish peroxidase transport study)]. / Vnutrigipotalamicheskie sviazi rostral'nogo i kaudal'nogo otdelov gipotalamusa (issledovanie metodom retrogradnogo aksonnogo transporta peroksidazy khrena).

Unilateral injections of 0.2--0.3 mkl 30% horseradish peroxidase (HP) Sigma VI were performed to 4 groups of rats: into the medial and lateral preoptic areas, into the medial and lateral areas of the caudal hypothalamus. After all injections performed the predominant amount of HP-positive neurons was found to situate ipsilaterally in the middle (tuberal) hypothalamic area, mainly in the frontal and lateral hypothalamic fields. Owing to the data obtained, it is possible to conclude that the tuberal hypothalamic areas mentioned are the source of the afferent innervation within the hypothalamus for its rostral and caudal parts.

[Cytophotometric study of the AChE-containing nerve cells and fibers of the rabbit heart after electrostimulation of the area hypothalamica posterior]. / Tsitofotometricheskoe issledovanie AKhE-soderzhashchikh nervnykh kletok i volokon serdtsa krolika posle élektrostimuliatsii area hypothalamica posterior.

By means of cytophotometry and a computer in the cardiac intramural neural plexus of 17 experimental and 17 control rabbits acetilcholine esterase (AChE) activity (revealed by Karnovsky--Roots' method) was investigated. It was stated that a prolonged electrostimulation of the area hypothalamica posterior (AHP) produced statistically significant 2-fold decrease of AChE activity in the cardiac neural cells and fibres. When the stimulation of AHP was stopped, the decreased enzymatic activity was observed for the first two weeks, then by the end of the 4th week it again reached its control level. The results of the work were discussed in view of possible disorders of regulating vegetative-trophic effects of the posterior hypothalamus on innervative and executive tissue elements of the heart.

[Nuclei and fields of the rabbit hypothalamus]. / Iadra i polia gipotalamusa krolika

Common features and distinctions in the structure of certain fields of the rabbit hypothalamus were established on the basis of cytoarchitectonical and cytological analysis. It has been shown that there are three types of nerve cells in the nuclei and fields of the hypothalamus which can be referred to somato-, cyto- and karyochromic elements of the nervous system in accordance with the Nissl classification. All the cellular structures of the hypothalamus can be divided into heteromorphic and isomorphic types. The medial and lateral hypothalamic fields of all the rostro-caudal length of the hypothalamus are referred to the first type. The hypothalamic nuclei occupying its basal part are referred to the second type. On the basis of the obtained data concerning the neuronal composition of the fields and nuclei of the hypothalamus, it can be divided into three zones: the medial zone, including 3 medial hypothalamic fields disposed along the 3d ventricle; the lateral zone comprizing two a lateral hypothalamic fields occupying its lateral parts along its all length and the basal zone including hypothalamic nuclei disposed mainly in the ventral part of the hypothalamus.