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Medicinas Tradicionales
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Nature ; 534(7606): 200-5, 2016 06 09.
Artículo en Inglés | MEDLINE | ID: mdl-27135931

RESUMEN

Modern humans arrived in Europe ~45,000 years ago, but little is known about their genetic composition before the start of farming ~8,500 years ago. Here we analyse genome-wide data from 51 Eurasians from ~45,000-7,000 years ago. Over this time, the proportion of Neanderthal DNA decreased from 3-6% to around 2%, consistent with natural selection against Neanderthal variants in modern humans. Whereas there is no evidence of the earliest modern humans in Europe contributing to the genetic composition of present-day Europeans, all individuals between ~37,000 and ~14,000 years ago descended from a single founder population which forms part of the ancestry of present-day Europeans. An ~35,000-year-old individual from northwest Europe represents an early branch of this founder population which was then displaced across a broad region, before reappearing in southwest Europe at the height of the last Ice Age ~19,000 years ago. During the major warming period after ~14,000 years ago, a genetic component related to present-day Near Easterners became widespread in Europe. These results document how population turnover and migration have been recurring themes of European prehistory.


Asunto(s)
Cubierta de Hielo , Población Blanca/genética , Población Blanca/historia , Animales , Evolución Biológica , ADN/análisis , ADN/genética , ADN/aislamiento & purificación , Europa (Continente) , Femenino , Efecto Fundador , Genética de Población , Historia Antigua , Migración Humana/historia , Humanos , Masculino , Medio Oriente , Hombre de Neandertal/genética , Filogenia , Dinámica Poblacional , Selección Genética , Análisis de Secuencia de ADN , Factores de Tiempo
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