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Artículo en Ruso | MEDLINE | ID: mdl-16447551

RESUMEN

A study of betahistine (betaserc) in 65 patients aged 59,48 +/- 8,63 years with vertigo in early rehabilitation period of ischemic stroke has been carried out. Thirty-five patients got atiplatelet and antihypertensive therapy and were also treated by betaserc--8-16 mg 3 times per day for 14 days per os, after meals. The control group of 30 patients received only atiplatelet and antihypertensive therapy. Both groups were similar in demographic and clinical characteristics. The treatment with betahistine reduced the intensity and duration of vertigo, led to improvement of coordination and equilibrium, increase stability of a vertical posture that was accompanied by significant (p<0,05) improvement of the values on the Hoffenberth and Bohannon scales. Betahistine treatment also resulted in marked authentic (p<0,05) improvement of stabilometric parameters in biological feedback task that might be explained by activation of the mechanisms maintaining vertical balance. An improvement of clinical and neurophysiologic traits was more pronounced in the group treated with betaserc as compared to the control group.


Asunto(s)
Betahistina/uso terapéutico , Biorretroalimentación Psicológica/fisiología , Desempeño Psicomotor/fisiología , Vasodilatadores/uso terapéutico , Insuficiencia Vertebrobasilar/fisiopatología , Vértigo/tratamiento farmacológico , Anciano , Antihipertensivos/uso terapéutico , Biorretroalimentación Psicológica/efectos de los fármacos , Quimioterapia Combinada , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Inhibidores de Agregación Plaquetaria/uso terapéutico , Desempeño Psicomotor/efectos de los fármacos , Resultado del Tratamiento , Insuficiencia Vertebrobasilar/complicaciones , Insuficiencia Vertebrobasilar/rehabilitación , Vértigo/etiología , Vértigo/fisiopatología
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