RESUMEN
INTRODUCTION: One of the important problems in modern dermatology is to improve treatment efficiency of acne being a common cause for cicatricial skin changes, loss of performance capability and social activity and negatively affects the psycho-emotional state of patients and their quality of life. The topicality of the disease is due to the high degree of its proliferation, chronic and recurrent course, and resistance to existing therapies. Reducing the effectiveness of skin diseases treatment, including that of acne, at present, is associated with developing resistance to drugs, which causes the use of non-drug methods in dermatology nowadays, including low-intensity laser therapy. Objective - to determine evolution of the systemic immunity indices in patients with acne with different degrees of severity in the course of a standard and comprehensive treatment by laser therapy. MATERIALS AND METHODS: We observed 77 patients with acne aged 18-25 years; 32 of them received standard therapy, other 45 patients were additionally prescribed combined (superficial venous and external) laser therapy. We determined the indices of all patients' systemic immunity using well-known techniques. RESULTS: It has been established, that using laser therapy in comprehensive treatment of patients with acne promotes the normalization or a tendency to normalization of the systemic immunity and phagocytosis with significant difference between the indices of the individuals who received a standard therapy alone.