Leveraging Statistical Theory In Sports Competitions: An Analysis Of Probabilistic Models And Multiple Regression Within The Framework Of Big Data

CBA is a sports event that allows fans to enjoy themselves and players to give full play, and traditional Chinese cultural values have a profound influence on it. This paper takes the 100 sets of historical rating data of the fourteen teams in CBA league as the basic basis, firstly, we simply deal with the 100 sets of historical rating data and use Excel function formula to find out the mean, extreme deviation and variance of each team, then we carry out SAS normal test, and we find that except for the very few data with large deviation, the historical rating data satisfy the normal distribution. Through the outlier algorithm to screen the values, compare the confidence intervals as well as carry out hypothesis testing, to objectively and scientifically explore the probability of each team winning the championship in the CBA league. Compare the probability of winning the championship of these fourteen teams and predict the top four teams in the CBA league to ensure that the prediction results are as reasonable as possible. With the help of hierarchical analysis to qualitatively analyze the level of each team, and then through cluster analysis to compare these data, and combined with the trend of the development of the world's basketball movement, the use of multiple regression and SPSS to analyze the level of the team's factors, in-depth thinking about the league, a more reasonable to give a more scientific to improve the probability of the team's winning the championship, and to promote better development of the basketball movement. (AU)

Methyl-Hispolon from Phellinus lonicerinus (Agaricomycetes) Affects Estrogen Signals in MCF-7 Breast Cancer Cells and Premature Aging in Rats.

We studied Phellinus lonicerinus to determine the cytotoxic effect and the dual estrogenic activities of methyl-hispolon and their relation to estrogen signals in vivo and in vitro. The Glide scores of methyl-hispolon-estrogen receptor α (ERα) and methyl-hispolon-ERß docked complexes were -7.29 kcal/mol and -6.68 kcal/mol in docking simulations. Methyl-hispolon had a significant antiproliferative effect for estrogen-sensitive ER(+) MCF-7 cells in the absence of estrogen, and it exhibited dual estrogen activities. Methyl-hispolon increased the serum E2 in rats with premature ovarian failure and fulfilled the estrogenic function in the uterus and ovary. Methyl-hispolon significantly inhibited the expression of Ras, API, ERα, C-myc, and cyclinDl, as well as their gene transcription in RL95-2 cells. The phosphorylation of ERK1/2 was inhibited by methyl-hispolon. Thus, methyl-hispolon has potential use in treating estrogen deficiency-related diseases, with good antitumor effects and estrogenic activity.

Protective mechanism of nicorandil on rat myocardial ischemia-reperfusion.

OBJECTIVES: To study the protective mechanism of nicorandil on myocardial ischemia-reperfusion injury. METHODS: Fifty rats were randomly divided into five groups, four of which were operated on to produce myocardial ischemia-reperfusion. Nicorandil (5 mg/kg) was administrated by intravenous injection to three of the groups. The myocardial ultrastructure was observed by electron microscope. The expression levels of the antiapoptotic protein Bcl-2 and the pro-apoptotic protein Bax were detected by immunohistochemical staining with rhodamine 123. The mitochondrial membrane potential was detected by spectrophotometry. RESULTS: The activity of lactate dehydrogenase (LDH) and malondialdehyde (MDA) content was decreased and the activity of superoxide dismutase (SOD) was increased in the three nicorandil groups, compared with those in the group without nicorandil (P < 0.01, P < 0.05). The positive staining level of the expressed Bcl-2 was increased and the expressed Bax was decreased (P < 0.01) in the three nicorandil groups, compared with those in the group without nicorandil. The mitochondrial inner membrane potential was increased in the three nicorandil groups compared with that in the group without nicorandil (P < 0.05). CONCLUSION: A suitable level of nicorandil has a protective effect on rats' myocardial ischemia-reperfusion injury, and is mainly based on the opening of the mitochondrial KATP channel and the lowing of Ca overload.