RESUMEN
It is currently thought that the incineration approach is an effective method to minimize the volume of radioactive wastes. In this paper, we used an incinerator to burn uranium-containing strippable coating waste. The migration behavior of radioactive uranium during the incineration process were investigated based on hierarchical sampling and mass spectrometry. Results shows that the radioactive uranium is more easily to adhere to the particles with smaller size. The leaching abilities of radioactive uranium in the bottom ash and the fly ash were analyzed. The leaching rate of the uranium from the fly ash and bottom ash were 1% and 6%, respectively, indicating that most of the radioactive uranium was fixed in the ash and the same storage/disposal methods can be used for both the fly ash and bottom ash. According to x-ray spectrometry and SEM-EDS, mineral compositions of the original uranium ore and the bottom ash were mostly the same. Calcium plays an important role in uranium fixation during incineration. The potential mechanism of the uranium special transformation during uranium-containing strippable coating waste combustion was revealed. Our research results can provide technical support for nuclear emergency waste treatment and disposal.
Asunto(s)
Metales Pesados , Residuos Radiactivos , Eliminación de Residuos , Uranio , Ceniza del Carbón/análisis , Incineración , Metales Pesados/análisis , Residuos Sólidos/análisisRESUMEN
Manganese transport protein C (MntC) of Staphylococcus aureus represents an excellent vaccine-candidate antigen. The important role of CD4+ T cells in effective immunity against S. aureus infection was shown; however, CD4+ T cell-specific epitopes on S. aureus MntC have not been well identified. Here, we used bioinformatics prediction algorithms to evaluate and identify nine candidate epitopes within MntC. Our results showed that peptide M8 emulsified in Freund's adjuvant induced a much higher cell-proliferation rate as compared with controls. Additionally, CD4+ T cells stimulated with peptide M8 secreted significantly higher levels of interferon-γ and interleukin-17A. These results suggested that peptide M8 represented an H-2d (I-E)-restricted Th17-specific epitope.
Asunto(s)
Linfocitos T CD4-Positivos/inmunología , Linfocitos T CD4-Positivos/metabolismo , Epítopos de Linfocito T/inmunología , Epítopos de Linfocito T/aislamiento & purificación , Manganeso/metabolismo , Proteína C/metabolismo , Staphylococcus aureus/inmunología , Staphylococcus aureus/metabolismo , Algoritmos , Secuencia de Aminoácidos , Animales , Antígenos Bacterianos/inmunología , Proteínas Bacterianas/inmunología , Proteínas Bacterianas/metabolismo , Citocinas/metabolismo , Mapeo Epitopo , Escherichia coli/genética , Femenino , Interferón gamma/metabolismo , Interleucina-17/metabolismo , Complejo Mayor de Histocompatibilidad , Ratones , Ratones Endogámicos BALB C , Proteína C/genética , Proteína C/inmunología , Estructura Secundaria de Proteína , Proteínas Recombinantes/inmunología , Infecciones Estafilocócicas/inmunología , Células TH1/inmunología , Células Th17/inmunologíaRESUMEN
There is considerable difference in the texts between PEF and the archaic editions Sun zhen ren qian jin fang (The Immortal Sun's Precious Formulary, ISPF) and the Song - revised edition Bei ji qian jin yao fang (Precious Essential Formulary for Emergency, PEFE). It is hoped that the real features of PEF can be worked out through collated studies on these two editions so as to offer a basis for systematic research on PEF. At the same time, it has been proved that during the revision and collation of PEF by the Song scholars, it is certain that dramatic revisions had been made on its medical materials, especially an abundant amount of medical materials were added. As a result, the current circulated edition of PEFE does have obvious differences with Sun's original work, while ISPF, in contrast, preserves the original features of Sun Simiao. Hence, ISPF is of important academic significance in the in - depth study of PEF.