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1.
Food Chem ; 446: 138866, 2024 Jul 15.
Artículo en Inglés | MEDLINE | ID: mdl-38430769

RESUMEN

Fresh-cut potatoes are prone to surface browning and physiological degradation. Chlorogenic acid (CGA), a natural phenolic antioxidant, has demonstrated preservative properties in various postharvest products. However, the underlying mechanisms of its application on maintaining quality remain unclear. Therefore, the effect of exogenous CGA treatment on quality deterioration of potato slices and the mechanisms involved were investigated. Results revealed CGA treatment retarded the browning coloration, suppressed microbial growth and inhibited the declines in starch, and ascorbic acid contents in potato slices. Meanwhile, the treatment activated the phenylpropanoid pathway but decreased the activities of phenolic decomposition-related enzymes such as polyphenol oxidase (PPO) and tyrosinase and downregulated StPPO expression. Moreover, the treated slices exhibited reduced accumulation of reactive oxygen species and increased activity of antioxidant enzymes. Additionally, they displayed enhanced 2,2-diphenyl-1-picrylhydrazyl radicals scavenging capacity and higher ATP levels. Therefore, these findings indicated that CGA treatment was effective for quality maintenance and antioxidant capacity enhancement in fresh-cut potatoes, thereby providing potential strategies for the preservation and processing of fresh-cut produce.


Asunto(s)
Antioxidantes , Solanum tuberosum , Antioxidantes/metabolismo , Ácido Clorogénico/farmacología , Ácido Clorogénico/metabolismo , Solanum tuberosum/metabolismo , Fenoles/metabolismo , Ácido Ascórbico/metabolismo , Catecol Oxidasa/metabolismo
2.
ACS Appl Mater Interfaces ; 12(18): 20307-20320, 2020 May 06.
Artículo en Inglés | MEDLINE | ID: mdl-32298570

RESUMEN

Wound bleeding and infection are two of the major threats to patients' lives, but developing safe materials with high hemostasis efficiency and antibacterial activity remains a major challenge. Silver nanoparticles (AgNPs) are suitable as antibacterial agents in the hemostatic process, but the application is hampered because of easy accumulation of toxicity. Herein, thiol-modified chitosan (TMC) was prepared by modifying with mercaptosuccinic acid and then was used to immobilize AgNPs to obtain composite sponges (TMC/AgNPs) for stemming the bleeding and preventing infection. TMC/AgNPs sponges had complex interlaced tubular porous structure with high porosity (99.42%), indicating high absorption. TMC had high immobilization efficiency for AgNPs-the release rate of AgNPs was 14.35% after 14 days-but the TMC/AgNPs sponge still had excellent antibacterial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. In vitro and in vivo experiments confirm that the TMC/AgNPs sponge had fast and efficient hemostatic performance in comparison with the PVF sponge, and its possible mechanism was the synergistic effect of high blood absorption capacity and the interaction between amino, sulfydryl, and blood cells. Furthermore, the TMC/AgNPs sponge can promote wound healing by preventing wound infection, while the PVF sponge cannot. More importantly, the sponges had good safety due to the immobilization of TMC for AgNPs.


Asunto(s)
Antibacterianos/uso terapéutico , Quitosano/análogos & derivados , Quitosano/uso terapéutico , Hemostáticos/uso terapéutico , Nanopartículas del Metal/uso terapéutico , Plata/uso terapéutico , Animales , Antibacterianos/toxicidad , Coagulación Sanguínea/efectos de los fármacos , Quitosano/toxicidad , Escherichia coli/efectos de los fármacos , Hemostáticos/toxicidad , Masculino , Nanopartículas del Metal/química , Nanopartículas del Metal/toxicidad , Ratones , Pruebas de Sensibilidad Microbiana , Pseudomonas aeruginosa/efectos de los fármacos , Conejos , Plata/química , Plata/toxicidad , Staphylococcus aureus/efectos de los fármacos , Tapones Quirúrgicos de Gaza , Cicatrización de Heridas/efectos de los fármacos
3.
Am J Perinatol ; 32(6): 503-14, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-25535930

RESUMEN

OBJECTIVES: The purpose of this article is to review all randomized control trials (RCTs) that have looked at the health effects of yoga on pregnancy, and to present their evidence on the specific ways in which pregnant women, and their infants can benefit from yoga intervention. The purpose is also to determine whether yoga intervention during pregnancy is more beneficial than other physical exercises. METHODS: Four databases were searched using the terms "yoga and (pregnancy or pregnant or prenatal or postnatal or postpartum)." Databases were searched from January 2004 to February 2014. RESULTS: Ten randomized controlled trials were evaluated. The findings consistently indicate that yoga intervention presented with lower incidences of prenatal disorders (p ≤ 0.05), and small gestational age (p < 0.05), lower levels of pain and stress (p < 0.05), and higher score of relationship (p < 0.05). In addition, yoga can be safely used for pregnant women who are depressed, at high-risk, or experience lumbopelvic pain. Moreover, yoga is a more effective exercise than walking or standard prenatal exercises. CONCLUSIONS: The findings suggest that yoga is a safe and more effective intervention during pregnancy. However, further RCTs are needed to provide firmer evidence regarding the utility and validity of yoga intervention.


Asunto(s)
Terapia por Ejercicio , Complicaciones del Embarazo/terapia , Mujeres Embarazadas/psicología , Yoga , Adulto , Depresión/terapia , Femenino , Humanos , Recién Nacido , Dolor/prevención & control , Embarazo , Ensayos Clínicos Controlados Aleatorios como Asunto
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