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Fitoterapia ; 159: 105198, 2022 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-35452746

RESUMEN

Four unknown meroterpenoids named as psidials D-G (1-4) together with 5 known compounds (5-9) had been obtained from the leaves of Psidium guajava. Their absolute structures were elucidated by spectral and calculated methods. Psidials DF (1-3) represented unknown carbon skeleton of the 3,5-diformylbenzyl phloroglucinol-coupled sesquiterpenoid. The possible biosynthetic pathway for 1-3 was postulated. In the bioactivity assay, psidial F (3) was found to possess anti-inflammatory and anticoagulant activities.


Asunto(s)
Psidium , Antiinflamatorios/farmacología , Anticoagulantes/farmacología , Estructura Molecular , Extractos Vegetales/análisis , Hojas de la Planta/química , Psidium/química , Esqueleto
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