RESUMEN
Objective:To investigate the effects and potential mechanism of vitamin D supplementation on testicular function in aging rats induced by D-galactose.Methods:The aging rats were induced by D-galactose with subcutaneous injection. The animals were randomly divided into 6 groups: aging rats (DG), aging rats with low-dose vitamin D supplementation (LD), aging rats with high-dose vitamin D supplementation (HD), normal control rats(NC), normal rats with low-dose vitamin D supplementation(LN), normal rats with high-dose vitamin D supplementation (HN). The body weight, testicular weight, serum testosterone concentrations and sperm quality of the rats in each group were measured. The testis morphological changes were detected using light microscopy. The activity of superoxide dismutase (SOD) and level of malondialdehyde(MDA) were determined with spectrophotometer. The expression levels of Nrf2, GCLC, SOD2 and VDR in testis were detected by western blot.Results:At baseline, compared with NC group, testicular weight, serum testosterone level, SOD activity, Nrf2, GCLC and SOD2 expression levels were significantly decreased in DG group, while MDA level was significantly increased. After vitamin D supplementation, testicular weight, testosterone levels and SOD activity in both of HD and LD groups were significantly increased, while the MDA level was significantly decreased. The expression levels of Nrf2, GCLC, SOD2 and VDR were significantly increased.Conclusion:Vitamin D supplementation may enhance the testicular antioxidant capacity through activating Nrf2-ARE signaling pathway, and improve the testicular function in D-galactose-induced aging rats.
RESUMEN
<p><b>OBJECTIVE</b>To explore the effects of the combined therapy of heat sensitive moxibustion and acupoint injection on endometrial receptivity of hypdrosalphinx infertility in the patients after hysteroscopy and laparoscopy on the base of routine post-operative anti-inflammation.</p><p><b>METHODS</b>A total of 210 patients of hypdrosalphinx infertility after hysteroscopy and laparoscopy were divided into a combined therapy group, a heat sensitive moxibustion group and a control group, 70 cases in each one according to the random number table. In the control group, the intravenous drip of cefoxitin sodium was adopted, and the anti-inflammation treatment was given for 1 week after operation. In the heat sensitive moxibustion group, on the basis of the treatment as the control group, the heat sensitive moxibustion was applied after vaginal bleeding stopped. The acupoints were Yaoyangguan (GV 3), Guanyuan (CV 4), Qihai (CV 6), Shenshu (BL 23), Sanyinjiao (SP 6), Yinlingquan (SP 9) and Zigong (EX-CA1). The acupoints were modified according to the different syndromes. In the combined therapy group, on the basis of the regimen as the heat sensitive moxibustion group, after vaginal bleeding stopped, the acupoint injection was given alternatively at bilateral Tiangong (extra, 1.0 cm inferior and bilateral to the cervix) with lidocaine 1 mL, amikacin 2 mL and salvia injection 2 mL. The treatment was given once every day, the treatment for 10 times as one course and a total of 3 courses were required. The endometrial type, thickness, uterine arterial plusatility index (PI) and resistance index (RI) were observed in the patients of each group.</p><p><b>RESULTS</b>After treatment, the numbers of A-type endometrial type in the combined therapy group and the heat sensitive moxibustion group were remarkably higher than those of the control group [57.1% (40/7) vs 31.4% (22/70), 50.0% (35/70) vs 31.4% (22/70), both<0.05]. The endometrial thickness after treatment was all increased as compared with that before treatment in each group (all<0.05). The increasing degree in the combined therapy group was better than either the heat sensitive moxibustion group or the control group (both<0.05). The improvement in the heat sensitive moxibustion group was superior to the control group (<0.05). PI and RI in the combination group and PI in the control group were decreased after treatment (all<0.05). The improvements of PI and RI in the combination group were better than those in the heat moxibustion group (both<0.05), which were superior to those in the control group (all<0.05).</p><p><b>CONCLUSION</b>In the patients of hypdrosalphinx infertility after hysteroscopy and laparoscopy, the combined therapy of heat sensitive moxibustion and acupoint injection increases endometrial thickness, reduces uterine arterial resistance and improves endometrial receptivity.</p>
RESUMEN
[Objectives]Observation of thermal moxibustion combined Ondansetron prevention and treatment of the effect of deficiency syndrome nausea and vomiting by malignant tumor chemotherapy,to explore using thermal moxibustion combined Ondansetron method,it can reduce the feasibility of chemotherapy induced gastrointestinal adverse reaction,to further improve the life quality of patients,provide safe effective treatment measures.[Method]60 patients were randomly divided into treatment group(30 cases) and control group(30 cases),two groups of patients had comprehensive chemotherapy regimens,control group adopted Ondansetron conventional anti-nausea,on the basis of the control group,treatment group with thermal moxibustion used Zhongwan,Shenque(CV 8),Neiguan(P6) Zusanli(ST36) and Weishu acupuncture points,and combined the Ondansetron treatment,the course of the treatment for 7 days,respectively,on day 1,day 3,7,record nausea and vomiting and appetite symptoms integral.Using SPSS18.0 software system,analysis and evaluation of the symptoms of different time points before and after treatment the change of the integral.[Results]Compared with control group,treatment group of nausea,vomiting,loss of appetite each score significantly lower than the control group,the difference had statistical significance(P＜0.05,P＜0.01)).[Conclusion]Thermal moxibustion combined with Ondansetron can effectively reduce the degree of deficiency syndrome nausea and vomiting caused by the malignant tumor chemotherapy,can effectively improve the patients' tolerance to chemotherapy.
RESUMEN
A famous doctors database of traditional Chinese medicine was developed and a platform for academic exchange between students , famous teachers and doctors was constructed with the running ideas and training modes of Shanxi College of Traditional Chinese Medicine Fushan School as an opportunity in order to hand down the clini-cal experiences and academic ideas in traditional Chinese medicine ,the native culture of traditional Chinese medi-cine in Shanxi Province and provide the platform for the elite education in Fushan School through academic ex-change and information resources sharing .
RESUMEN
The online teaching quality assessment system that was established by embedding the professional knowledge into the teaching of literature retrieval course, can help the students master the methods and skills to ac-cess and use the literature information they need and the basic knowledge of subjects in which they major .
RESUMEN
Now syndrome study becomes the important research content in our country' TCM field,normalization of the symptoms standardization of syndromes especially becomes scientific research focal point in this field,furthermore some studies exists the conditions of symptoms short of norm and standards of syndrome differentiation discordant,as well stagnation of liver-QI with deficiency of the spleen is clinical common syndrome,so this article carried out all round analysis and investigations on the modern literature of stagnation of liver-QI with deficiency of the spleen syndrome recent ten years,to aim at analyzing the symptom characteristic and standards of syndrome differentiation on stagnation of liver-QI with deficiency of the spleen syndrome,to provide the bases of standardization and normalization of stagnation of liver-QI with deficiency of the spleen syndrome.