Recent advances in implantable sensors and electronics using printable materials for advanced healthcare.

This review article focuses on the recent printing technological progress in healthcare, underscoring the significant potential of implantable devices across diverse applications. Printing technologies have widespread use in developing health monitoring devices, diagnostic systems, and surgical devices. Recent years have witnessed remarkable progress in fabricating low-profile implantable devices, driven by advancements in printing technologies and nanomaterials. The importance of implantable biosensors and bioelectronics is highlighted, specifically exploring printing tools using bio-printable inks for practical applications, including a detailed examination of fabrication processes and essential parameters. This review also justifies the need for mechanical and electrical compatibility between bioelectronics and biological tissues. In addition to technological aspects, this article delves into the importance of appropriate packaging methods to enhance implantable devices' performance, compatibility, and longevity, which are made possible by integrating cutting-edge printing technology. Collectively, we aim to shed light on the holistic landscape of implantable biosensors and bioelectronics, showcasing their evolving role in advancing healthcare through innovative printing technologies.

An EMG-based Eating Behaviour Monitoring system with haptic feedback to promote mindful eating.

Mindless eating, or the lack of awareness of the food we are consuming, has been linked to health problems attributed to unhealthy eating behaviour, including obesity. Traditional approaches used to moderate eating behaviour often rely on inaccurate self-logging, manual observations or bulky equipment. Overall, there is a clear unmet clinical need to develop an intelligent and lightweight system which can automatically monitor eating behaviour and provide feedback. In this paper, we investigate: i) the development of an automated system for detecting eating behaviour using wearable Electromyography (EMG) sensors, and ii) the application of the proposed system combined with real-time wristband haptic feedback to facilitate mindful eating. For this, the collected data from 16 participants were used to develop an algorithm for detecting chewing and swallowing. We extracted 18 features from EMG which were presented to different classifiers, to develop a system enabling participants to self-moderate their chewing behaviour using haptic feedback. An additional experimental study was conducted with 20 further participants to evaluate the effectiveness of eating monitoring and haptic interface in promoting mindful eating. We used a standard validation scheme with a leave-one-participant-out to assess model performance using standard metrics (F1-score). The proposed algorithm automatically assessed eating behaviour accurately using the EMG-extracted features and a Support Vector Machine (SVM): F1-Score = 0.95 for chewing classification, and F1-Score = 0.87 for swallowing classification. The experimental study showed that participants exhibited a lower rate of chewing when haptic feedback was delivered in the form of wristband vibration, compared to a baseline and non-haptic condition (F (2,38) = 58.243, p < .001). These findings may have major implications for research in eating behaviour, providing key insights into the impact of automatic chewing detection and haptic feedback systems on moderating eating behaviour towards improving health outcomes.

Flexible Electronics: An Epidermal Stimulation and Sensing Platform for Sensorimotor Prosthetic Control, Management of Lower Back Exertion, and Electrical Muscle Activation (Adv. Mater. 22/2016).

The design of an ultrathin, conformal electronic device that integrates electrotactile stimulation with electromyography, temperature, and strain sensing in a single, simple platform is reported by J. A. Rogers and co-workers on page 4462. Demonstrated application possibilities include prosthetic control with sensory feedback, monitors, and stimulation signals related to lower back exertion, and electrical muscle stimulation with feedback control.

An Epidermal Stimulation and Sensing Platform for Sensorimotor Prosthetic Control, Management of Lower Back Exertion, and Electrical Muscle Activation.

The design of an ultrathin, conformal electronic device that integrates electrotactile stimulation with electromyography, temperature, and strain sensing in a single, simple platform is reported. Experiments demonstrate simultaneous use of multiple modes of operation of this type of device in the sensorimotor control of robotic systems, in the monitoring of lower back exertion and in muscle stimulation.