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J Med Virol ; 92(7): 909-914, 2020 07.
Artículo en Inglés | MEDLINE | ID: mdl-32222992

RESUMEN

Coronavirus Disease 2019 (COVID-19) is a newly emerging infectious disease caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). After its first occurrence in Wuhan of China from December 2019, COVID-19 rapidly spread around the world. According to the World Health Organization statement on 13 March 2020, there had been over 132 500 confirmed cases globally. Nevertheless, the case reports of children are rare, which results in the lack of evidence for preventing and controlling of children's infection. Here, we report three cases of SARS-CoV-2 infected children diagnosed from 3 February to 17 February 2020 in Tianjin, China. All of these three cases experienced mild illness and recovered soon after the treatment, with the nucleic acid of throat swab turning negative within 14, 11, and 7 days after diagnosis, respectively. However, after been discharged, all three cases were tested SARS-CoV-2 positive in the stool samples within 10 days, in spite of their remained negative nucleic acid in throat swab specimens. Therefore, it is necessary to be aware of the possibility of fecal-oral transmission of SARS-CoV-2 infection, especially for children cases.


Asunto(s)
Betacoronavirus/genética , Técnicas de Laboratorio Clínico/métodos , Convalecencia , Infecciones por Coronavirus/diagnóstico , Neumonía Viral/diagnóstico , ARN Viral/sangre , Ácido Ascórbico/uso terapéutico , Betacoronavirus/efectos de los fármacos , Betacoronavirus/patogenicidad , Biomarcadores/sangre , COVID-19 , Prueba de COVID-19 , Ceftriaxona/uso terapéutico , Niño , China , Infecciones por Coronavirus/tratamiento farmacológico , Infecciones por Coronavirus/transmisión , Infecciones por Coronavirus/virología , Medicamentos Herbarios Chinos/uso terapéutico , Heces/virología , Humanos , Interferones/uso terapéutico , Masculino , Pandemias , Alta del Paciente , Faringe/virología , Neumonía Viral/tratamiento farmacológico , Neumonía Viral/transmisión , Neumonía Viral/virología , ARN Viral/genética , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , Ribavirina/uso terapéutico , SARS-CoV-2 , Tomografía Computarizada por Rayos X
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