RESUMEN
Wet-tissue adhesives have long been attractive materials for realizing complicated biomedical functions. However, the hydration film on wet tissues can generate a boundary, forming hydrogen bonds with the adhesives that weaken adhesive strength. Introducing black phosphorus (BP) is believed to enhance the water absorption capacity of tape-type adhesives and effectively eliminate hydration layers between the tissue and adhesive. This study reports a composite patch integrated with BP nanosheets (CPB) for wet-tissue adhesion. The patch's improved water absorption and mechanical properties ensure its immediate and robust adhesion to wet tissues. Various bioapplications of CPB are demonstrated, such as rapid hemostasis (within ~1-2 seconds), monitoring of physical-activity and prevention of tumour-recurrence, all validated via in vivo studies. Given the good practicability, histocompatibility and biodegradability of CPB, the proposed patches hold significant promise for a wide range of biomedical applications.
Asunto(s)
Adhesivos Tisulares , Agua , Humanos , Agua/química , Fósforo , Adherencias Tisulares , Adhesivos/química , Adhesivos Tisulares/química , HidrogelesRESUMEN
The use of energy therapy including tourmaline/negative ions has gained huge popularity due to their long-standing historical evidence in improving human health and the technology development. However, the limitations of tourmaline based polyurethane fibers including the unsatisfied mechanical properties and negative ions releasing performances hind their further applications for wearable energy therapy. In this study, graphene oxide was modified within the polyurethane/tourmaline nanocomposite and then the wet-spinning method was used to prepare the fibers. As expected, the results proved that polyurethane/tourmaline/graphene oxide fiber had enhanced Young's modulus (8.4 MPa) and tensile stain at break (335%). In addition, the number of released negative ions from polyurethane/tourmaline/graphene oxide fiber was significantly improved 17 times and 1.6 times more than that of neat polyurethane fiber and polyurethane/tourmaline fiber, respectively. Moreover, the releasing number of negative ions was significantly decreased after being applying voltage. We envision that the proposed polyurethane/tourmaline/graphene oxide fiber will provide valuable insights into the development of the wearable energy products.