RESUMEN
Anastomosing of the uterine horns in 98 experimental rats has employed a fibrin glue FK-1 (USSR) and Beriplast (FRG) or microsurgical techniques in a control group. Intactness and sealing of the anastomoses and the incidence of pelvic adhesions were assessed at 5 minutes, 1 hour and 1, 2, 3, 4, 5, and 6 days following the operation. The fibrin glue Beriplast was used clinically in 6 patients during reconstructive-plastic operations. The results with seamless anastomosing of uterine horns in rats using the fibrin glue and preliminary clinical evidence suggests a high effectiveness of the glue in gynecologic reconstructive plastic surgery.
Asunto(s)
Enfermedades de las Trompas Uterinas/cirugía , Adhesivo de Tejido de Fibrina/administración & dosificación , Enfermedades Uterinas/cirugía , Anastomosis Quirúrgica/métodos , Animales , Evaluación Preclínica de Medicamentos , Femenino , Humanos , Ratas , Útero/cirugíaRESUMEN
In animal experiments on rabbits the effect of hyperbaric oxygen was studied on the functional state of the myocardium, the cardiac resistance to induced peroxide lipid oxidation, the structural and functional changes in the thyroid gland and the state of microcirculation in the conditions of experimentally induced hypothyrosis. It was demonstrated that hyperbaric oxygen has a favourable effect on the state of myocardium and microcirculation.
Asunto(s)
Oxigenoterapia Hiperbárica , Hipotiroidismo/terapia , Animales , Modelos Animales de Enfermedad , Corazón/fisiopatología , Hipotiroidismo/fisiopatología , Peroxidación de Lípido , Masculino , Microcirculación/fisiopatología , Músculos/irrigación sanguínea , Miocardio/metabolismo , Miocardio/patología , Conejos , Glándula Tiroides/irrigación sanguínea , Glándula Tiroides/patologíaRESUMEN
The time course of the local tissue blood flow in the small intestinal graft used for esophagoplasty was studied in 54 acute experiments on rabbits exposed to hyperbaric oxygenation (1 hour, 2 ata). It has been shown that hyperbaric oxygenation prevents alterations in the local tissue blood flow in the small intestine. This fact provides evidence in favour of hyperbaric oxygenation application under clinical conditions.