RESUMEN
OBJECTIVE: To study the optimum extraction factors of Buxueyangyan Mixture. METHOD: The orthogonal design was used to select the optimum extraction factors of Cervi Pantotrichum etc. and water extraction rate was used to evaluate the factors. The orthogonal desingn was used to study three factors including crude particle size, extraction time and amount of water. Lcariine content was used as analytical parameter. RESULT: The optimum extraction factors for Cervi Pantotrichum etc. were: 3 a volume ofwith 10 times of water used for three extraction 2.5 h each time. The optimum extraction factors for others were: 1 cm or smaller the crude particle size, boiling 2 times: 2.5, 1.5 h respectively the amount of water used was 10. 8 times of the drug mixture respectively. CONCLUSION: According the optimum extraction factors, the active substance can be extracted efficiently.