Búsqueda | BVS Medicinas Tradicionales, Complementarias, e Integrativas en las Américas

1.

Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.

Shenderov, Kevin; Barber, Daniel L; Mayer-Barber, Katrin D; Gurcha, Sudagar S; Jankovic, Dragana; Feng, Carl G; Oland, Sandy; Hieny, Sara; Caspar, Pat; Yamasaki, Sho; Lin, Xin; Ting, Jenny P-Y; Trinchieri, Giorgio; Besra, Gurdyal S; Cerundolo, Vincenzo; Sher, Alan.

J Immunol ; 190(11): 5722-30, 2013 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-23630357

2.

A rapid fluorescence-based assay for classification of iNKT cell activating glycolipids.

Arora, Pooja; Venkataswamy, Manjunatha M; Baena, Andres; Bricard, Gabriel; Li, Qian; Veerapen, Natacha; Ndonye, Rachel; Park, Jeong Ju; Lee, Ji Hyung; Seo, Kyung-Chang; Howell, Amy R; Chang, Young-Tae; Illarionov, Petr A; Besra, Gurdyal S; Chung, Sung-Kee; Porcelli, Steven A.

J Am Chem Soc ; 133(14): 5198-201, 2011 Apr 13.

Artículo en Inglés | MEDLINE | ID: mdl-21425779

3.

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.

Veerapen, Natacha; Reddington, Faye; Salio, Mariolina; Cerundolo, Vincenzo; Besra, Gurdyal S.

Bioorg Med Chem ; 19(1): 221-8, 2011 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-21145749

4.

Identification and characterization of aspartyl-tRNA synthetase inhibitors against Mycobacterium tuberculosis by an integrated whole-cell target-based approach.

Soto, Ramón; Perez-Herran, Esther; Rodriguez, Beatriz; Duma, Bogdan M; Cacho-Izquierdo, Monica; Mendoza-Losana, Alfonso; Lelievre, Joel; Aguirre, David Barros; Ballell, Lluis; Cox, Liam R; Alderwick, Luke J; Besra, Gurdyal S.

Sci Rep ; 8(1): 12664, 2018 08 23.

Artículo en Inglés | MEDLINE | ID: mdl-30140040

5.

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.

Machutta, Carl A; Kollmann, Christopher S; Lind, Kenneth E; Bai, Xiaopeng; Chan, Pan F; Huang, Jianzhong; Ballell, Lluis; Belyanskaya, Svetlana; Besra, Gurdyal S; Barros-Aguirre, David; Bates, Robert H; Centrella, Paolo A; Chang, Sandy S; Chai, Jing; Choudhry, Anthony E; Coffin, Aaron; Davie, Christopher P; Deng, Hongfeng; Deng, Jianghe; Ding, Yun; Dodson, Jason W; Fosbenner, David T; Gao, Enoch N; Graham, Taylor L; Graybill, Todd L; Ingraham, Karen; Johnson, Walter P; King, Bryan W; Kwiatkowski, Christopher R; Lelièvre, Joël; Li, Yue; Liu, Xiaorong; Lu, Quinn; Lehr, Ruth; Mendoza-Losana, Alfonso; Martin, John; McCloskey, Lynn; McCormick, Patti; O'Keefe, Heather P; O'Keeffe, Thomas; Pao, Christina; Phelps, Christopher B; Qi, Hongwei; Rafferty, Keith; Scavello, Genaro S; Steiginga, Matt S; Sundersingh, Flora S; Sweitzer, Sharon M; Szewczuk, Lawrence M; Taylor, Amy.

Nat Commun ; 8: 16081, 2017 07 17.

Artículo en Inglés | MEDLINE | ID: mdl-28714473

6.

Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen.

Cox, Jonathan A G; Mugumbate, Grace; Del Peral, Laura Vela-Glez; Jankute, Monika; Abrahams, Katherine A; Jervis, Peter; Jackenkroll, Stefan; Perez, Arancha; Alemparte, Carlos; Esquivias, Jorge; Lelièvre, Joël; Ramon, Fernando; Barros, David; Ballell, Lluis; Besra, Gurdyal S.

Sci Rep ; 6: 38986, 2016 12 16.

Artículo en Inglés | MEDLINE | ID: mdl-27982051

7.

7000 year-old tuberculosis cases from Hungary - Osteological and biomolecular evidence.

Masson, Muriel; Bereczki, Zsolt; Molnár, Erika; Donoghue, Helen D; Minnikin, David E; Lee, Oona Y-C; Wu, Houdini H T; Besra, Gurdyal S; Bull, Ian D; Pálfi, György.

Tuberculosis (Edinb) ; 95 Suppl 1: S13-7, 2015 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-25736538

8.

Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation.

Mugumbate, Grace; Abrahams, Katherine A; Cox, Jonathan A G; Papadatos, George; van Westen, Gerard; Lelièvre, Joël; Calus, Szymon T; Loman, Nicholas J; Ballell, Lluis; Barros, David; Overington, John P; Besra, Gurdyal S.

PLoS One ; 10(3): e0121492, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-25799414

9.

The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.

Newton, Sandra M; Lau, Clara; Gurcha, Sudagar S; Besra, Gurdyal S; Wright, Colin W.

J Ethnopharmacol ; 79(1): 57-67, 2002 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-11744296

10.

Osteological and biomolecular evidence of a 7000-year-old case of hypertrophic pulmonary osteopathy secondary to tuberculosis from neolithic hungary.

Masson, Muriel; Molnár, Erika; Donoghue, Helen D; Besra, Gurdyal S; Minnikin, David E; Wu, Houdini H T; Lee, Oona Y-C; Bull, Ian D; Pálfi, György.

PLoS One ; 8(10): e78252, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-24205173

11.

Synthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636.

Bhowruth, Veemal; Brown, Alistair K; Besra, Gurdyal S.

Microbiology (Reading) ; 154(Pt 7): 1866-1875, 2008 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-18599816

12.

Synthesis and biological evaluation of new inhibitors of UDP-Galf transferase--a key enzyme in M. tuberculosis cell wall biosynthesis.

Cren, Sylvaine; Gurcha, Sudagar S; Blake, Alexander J; Besra, Gurdyal S; Thomas, Neil R.

Org Biomol Chem ; 2(17): 2418-20, 2004 Sep 07.

Artículo en Inglés | MEDLINE | ID: mdl-15326520

13.

The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis

Newton, Sandra M; Lau, Clara; Gurcha, Sudagar S; Besra, Gurdyal S; Wright, Colin W.

s.l; s.n; 2002. 11 p. ilus, tab.

No convencional en Inglés | SES-SP, HANSEN, Hanseníase, SESSP-ILSLACERVO, SES-SP | ID: biblio-1240983

BVS Medicinas Tradicionales, Complementarias, e Integrativas en las Américas - MTCI

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