Búsqueda | BVS Medicinas Tradicionales, Complementarias, e Integrativas en las Américas

Gueiffier, A; Mavel, S; Lhassani, M; Elhakmaoui, A; Snoeck, R; Andrei, G; Chavignon, O; Teulade, J C; Witvrouw, M; Balzarini, J; De Clercq, E; Chapat, J P.

J Med Chem ; 41(25): 5108-12, 1998 Dec 03.

Artículo en Inglés | MEDLINE | ID: mdl-9836626

13.

A conformational and structure-activity relationship study of cytotoxic 3,5-bis(arylidene)-4-piperidones and related N-acryloyl analogues.

Dimmock, J R; Padmanilayam, M P; Puthucode, R N; Nazarali, A J; Motaganahalli, N L; Zello, G A; Quail, J W; Oloo, E O; Kraatz, H B; Prisciak, J S; Allen, T M; Santos, C L; Balzarini, J; De Clercq, E; Manavathu, E K.

J Med Chem ; 44(4): 586-93, 2001 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-11170648

14.

Chicoric acid analogues as HIV-1 integrase inhibitors.

Lin, Z; Neamati, N; Zhao, H; Kiryu, Y; Turpin, J A; Aberham, C; Strebel, K; Kohn, K; Witvrouw, M; Pannecouque, C; Debyser, Z; De Clercq, E; Rice, W G; Pommier, Y; Burke, T R.

J Med Chem ; 42(8): 1401-14, 1999 Apr 22.

Artículo en Inglés | MEDLINE | ID: mdl-10212126

15.

Influence of S-adenosylhomocysteine hydrolase inhibitors on S-adenosylhomocysteine and S-adenosylmethionine pool levels in L929 cells.

Cools, M; De Clercq, E.

Biochem Pharmacol ; 40(10): 2259-64, 1990 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-2244927

16.

Mechanism of the synergistic antiviral and cytostatic activity of (RS)-3-(adenin-9-yl)-2-hydroxypropanoic acid isobutyl ester and D,L-homocysteine.

Cools, M; Hasobe, M; De Clercq, E; Borchardt, R T.

Biochem Pharmacol ; 39(1): 195-202, 1990 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-2297354

17.

Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method.

Kodama, E; Shigeta, S; Suzuki, T; De Clercq, E.

Antiviral Res ; 31(3): 159-64, 1996 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-8811200

18.

Synthesis and antiviral activity evaluation of 3'-fluoro-3'-deoxyribonucleosides: broad-spectrum antiviral activity of 3'-fluoro-3'-deoxyadenosine.

Van Aerschot, A; Herdewijn, P; Janssen, G; Cools, M; De Clercq, E.

Antiviral Res ; 12(3): 133-50, 1989 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-2624455

19.

The mannose-specific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine)n-specific plant lectin from Urtica dioica are potent and selective inhibitors of human immunodeficiency virus and cytomegalovirus replication in vitro.

Balzarini, J; Neyts, J; Schols, D; Hosoya, M; Van Damme, E; Peumans, W; De Clercq, E.

Antiviral Res ; 18(2): 191-207, 1992 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-1329650

20.

Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines.

De Clercq, E; Sakuma, T; Baba, M; Pauwels, R; Balzarini, J; Rosenberg, I; Holý, A.

Antiviral Res ; 8(5-6): 261-72, 1987 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-3451698

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Biologically active bisbenzylisoquinoline alkaloids from the root bark of Epinetrum villosum.

Synthesis and biological evaluation of N- and O-alkylated bicyclic furanopyrimidines as non-nucleosidic inhibitors of human cytomegalovirus.

2-(2,6-Dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors.

Structure-activity relationship of novel oligopeptide antiviral and antitumor agents related to netropsin and distamycin.

cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system.

Synthesis and cytostatic activity of geiparvarin analogues.

Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters.

Geiparvarin analogues. 4. Synthesis and cytostatic activity of geiparvarin analogues bearing a carbamate moiety or a furocoumarin fragment on the alkenyl side chain.

Geiparvarin analogues. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain.

Doubly homologated dihalovinyl and acetylene analogues of adenosine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects.

Geiparvarin analogues. 2. Synthesis and cytostatic activity of 5-(4-arylbutadienyl)-3(2H)-furanones and of N-substituted 3-(4-oxo-2-furanyl)-2-buten-2-yl carbamates.

Synthesis of imidazo[1,2-a]pyridines as antiviral agents.