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J Adolesc Health ; 26(4): 295-302, 2000 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-10734277


PURPOSE: The purpose of this study was to describe the spectrum of adolescent spirituality and to determine the association between dimensions of spirituality and voluntary sexual activity (VSA) in adolescents. DESIGN: A sample of 141 consecutive youth aged 11-25 years presenting to an urban, hospital-based adolescent medicine clinic completed a 153-item instrument assessing sociodemographics, psychosocial parameters, and eight specific aspects of spirituality including: (1) religious attendance, (2) religious importance, (3) intrinsic and (4) extrinsic religious motivation, (5) belief in God, (6) belief in divine support, (7) existential aspects of spirituality, and (8) spiritual interconnectedness. Adolescents were also asked about VSA. RESULTS: Sixty-one percent of respondents were African-American and 67.4%, female; mean age was 16.0+/-2.4 years. Adolescent religious attendance was equally distributed across the categories from "none" to "weekly or greater" attendance. Over 90% felt religion was somewhat important in their lives. Over 85% reported belief in God. Fifty-six percent of respondents reported a history of VSA. Greater importance of religion (p = 0.035) and higher spiritual interconnectedness with friends (p = 0.033) were inversely associated with VSA. A multiple logistic regression model including age, gender, race, socioeconomic status, and specific denomination of religious faith, importance of religion, and spiritual interconnectedness found that spiritual interconnectedness with friends (OR = 0.92, 95% CI = 0.85, 0.99) and age (OR = 1.75, 95% CI = 1.34, 2.28) were independent predictors of VSA. CONCLUSIONS: Spirituality is a common facet of adolescents' lives. Younger age and higher spiritual interconnectedness, particularly interconnectedness among spiritual friends, are independently associated with a lower likelihood of VSA.

Psicología del Adolescente , Religión y Psicología , Conducta Sexual/psicología , Adolescente , Intervalos de Confianza , Femenino , Humanos , Masculino , Oportunidad Relativa , Psicología del Adolescente/estadística & datos numéricos , Psicología Social , Conducta Sexual/estadística & datos numéricos , Factores Socioeconómicos , Estadísticas no Paramétricas , Encuestas y Cuestionarios , Población Urbana/estadística & datos numéricos
Science ; 254(5034): 1022-4, 1991 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-1658940


A calcitonin receptor complementary DNA (cDNA) was cloned by expression of a cDNA library from a porcine kidney epithelial cell line in COS cells. The 482-amino acid receptor has high affinity for salmon calcitonin (dissociation constant Kd approximately 6 nM) and is functionally coupled to increases in intracellular cyclic adenosine monophosphate (cAMP). The receptor shows no sequence similarity to other reported G protein-coupled receptors but is homologous to the parathyroid hormone-parathyroid hormone-related peptide (PTH-PTHrP) receptor, indicating that the receptors for these hormones, which regulate calcium homeostasis, represent a new family of G protein-coupled receptors.

Calcitonina/metabolismo , Receptores de Superficie Celular/genética , Adenilil Ciclasas/fisiología , Secuencia de Aminoácidos , Animales , Northern Blotting , Clonación Molecular , AMP Cíclico/fisiología , ADN/genética , Expresión Génica , Riñón/fisiología , Datos de Secuencia Molecular , ARN Mensajero/genética , Receptores de Calcitonina , Porcinos