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Métodos Terapéuticos y Terapias MTCI
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1.
Cancer Treat Rep ; 63(5): 789-91, 1979 May.
Artículo en Inglés | MEDLINE | ID: mdl-455316

RESUMEN

A phase II evaluation of anguidine was carried out in 30 patients with advanced refractory breast cancer. A dose of 5.0 mg/m2 daily for 5 days was explored. The main toxic effects were nausea and vomiting, fever and chills, hypotension, skin erythema, somnolence, confusion, and lethargy. Myelosuppression was minimal. Among these extensively pretreated patients, there was one partial responder and one additional patient who showed improvement (less than a partial response); both responses occurred in soft tissue sites.


Asunto(s)
Antineoplásicos Fitogénicos/uso terapéutico , Neoplasias de la Mama/tratamiento farmacológico , Sesquiterpenos/uso terapéutico , Tricotecenos/uso terapéutico , Adulto , Anciano , Antineoplásicos Fitogénicos/efectos adversos , Neoplasias de la Mama/patología , Femenino , Fusarium , Humanos , Persona de Mediana Edad , Tricotecenos/efectos adversos
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