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Integr Cancer Ther ; 15(3): 250-62, 2016 09.
Artículo en Inglés | MEDLINE | ID: mdl-26867802


Hypothesis This study examines moderators and mediators of a yoga intervention targeting quality-of-life (QOL) outcomes in women with breast cancer receiving radiotherapy.Methods Women undergoing 6 weeks of radiotherapy were randomized to a yoga (YG; n = 53) or stretching (ST; n = 56) intervention or a waitlist control group (WL; n = 54). Depressive symptoms and sleep disturbances were measured at baseline. Mediator (posttraumatic stress symptoms, benefit finding, and cortisol slope) and outcome (36-item Short Form [SF]-36 mental and physical component scales [MCS and PCS]) variables were assessed at baseline, end-of-treatment, and 1-, 3-, and 6-months posttreatment. Results Baseline depressive symptoms (P = .03) and sleep disturbances (P < .01) moderated the Group × Time effect on MCS, but not PCS. Women with high baseline depressive symptoms in YG reported marginally higher 3-month MCS than their counterparts in WL (P = .11). Women with high baseline sleep disturbances in YG reported higher 3-months MCS than their counterparts in WL (P < .01) and higher 6-month MCS than their counterparts in ST (P = .01). YG led to greater benefit finding than ST and WL across the follow-up (P = .01). Three-month benefit finding partially mediated the effect of YG on 6-month PCS. Posttraumatic stress symptoms and cortisol slope did not mediate treatment effect on QOL. Conclusion Yoga may provide the greatest mental-health-related QOL benefits for those experiencing pre-radiotherapy sleep disturbance and depressive symptoms. Yoga may improve physical-health-related QOL by increasing ability to find benefit in the cancer experience.

Neoplasias de la Mama/psicología , Neoplasias de la Mama/radioterapia , Meditación/psicología , Yoga/psicología , Neoplasias de la Mama/metabolismo , Depresión/metabolismo , Depresión/psicología , Fatiga/psicología , Femenino , Humanos , Hidrocortisona/metabolismo , Persona de Mediana Edad , Calidad de Vida , Trastornos del Sueño-Vigilia/metabolismo , Trastornos del Sueño-Vigilia/psicología
Complement Ther Med ; 20(6): 424-30, 2012 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23131373


BACKGROUND: Neurogenic bladder dysfunction (NBD) is a common distressful symptom in multiple sclerosis (MS) affecting quality of life. Yoga has been widely used in treating various symptoms of patients with MS. OBJECTIVES: To evaluate the effect of integrated Yoga for NBD in patients with MS as an adjunct to standard medical care. DESIGN: This open arm, pre-post study design assessed the outcome measures at base line and after 21 days of integrated Yoga intervention. SETTING: study was conducted at the center for neurological rehabilitation at KWA-Klinik Stift Rottal in Bad Griesbach, Germany. Eleven MS patients with NBD (mean age 46.7±11.24 years) with mean duration 17.2 years volunteered to participate in the study. INTERVENTIONS: integrated Yoga which includes preparatory yogic loosening and breathing practices, Nadishuddi pranayama (alternate nostril breathing), moola bandha (anal lock), kapalbhati (rapid nostril breathing) and deep relaxation technique was given for 2h per day for continuous 21 days. OUTCOME MEASURES: ultrasound scanning for post void residual urine volume (PVR), micturition check list (MCL), incontinence impact questionnaire-7 (IIQ-7) andurogenital distress inventory-6 (UDI-6) were used. RESULTS: Paired sample t-test showed significant improvement in post void residual urine (62.34%, p<0.05), scores on micturition frequency checklist (25%, p<0.05), incontinence impact questionnaire-7 (32.77%, p<0.05) and uro-genital distress inventory-6 (26.33%, p<0.05). CONCLUSION: This study points to the safety and effectiveness of integrated Yoga for bladder symptoms as an adjunct to standard care in multiple sclerosis patients with neurogenic bladder dysfunction in Germany. Further trails are necessary to confirm these findings.

Meditación , Esclerosis Múltiple/terapia , Terapia por Relajación , Vejiga Urinaria Neurogénica/terapia , Vejiga Urinaria/patología , Micción , Yoga , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Esclerosis Múltiple/complicaciones , Observación , Estudios Prospectivos , Investigación Cualitativa , Centros de Rehabilitación , Encuestas y Cuestionarios , Vejiga Urinaria Neurogénica/complicaciones , Incontinencia Urinaria/etiología , Incontinencia Urinaria/terapia
J Soc Integr Oncol ; 8(2): 43-55, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-20388445


This study examined the effects of yoga on quality of life (QOL) and psychosocial outcomes in women with breast cancer undergoing radiotherapy. Sixty-one women were randomly assigned to either a yoga or a wait-list group. Yoga classes were taught biweekly during the 6 weeks of radiotherapy. Participants completed measures of QOL, fatigue, benefit finding (finding meaning in the cancer experience), intrusive thoughts, sleep disturbances, depressive symptoms, and anxiety before radiotherapy and then again 1 week, 1 month, and 3 months after the end of radiotherapy. General linear model analyses revealed that compared to the control group, the yoga group reported significantly better general health perception (p = .005) and physical functioning scores (p = .04) 1 week postradiotherapy; higher levels of intrusive thoughts 1 month postradiotherapy (p = .01); and greater benefit finding 3 months postradiotherapy (p = .01). There were no other group differences in other QOL subscales for fatigue, depression, or sleep scores. Exploratory analyses indicated that intrusive thoughts 1 month after radiotherapy were significantly positively correlated with benefit finding 3 months after radiotherapy (r = .36, p = .011). Our results indicated that the yoga program was associated with statistically and clinically significant improvements in aspects of QOL.

Calidad de Vida , Yoga , Neoplasias de la Mama/psicología , Depresión , Fatiga , Femenino , Humanos