Búsqueda | BVS Medicinas Tradicionales, Complementarias, e Integrativas en las Américas

1.

Maternal overnutrition programs epigenetic changes in the regulatory regions of hypothalamic Pomc in the offspring of rats.

Gali Ramamoorthy, Thanuja; Allen, Tiffany-Jayne; Davies, Alison; Harno, Erika; Sefton, Charlotte; Murgatroyd, Christopher; White, Anne.

Int J Obes (Lond) ; 42(8): 1431-1444, 2018 08.

Artículo en Inglés | MEDLINE | ID: mdl-29777232

2.

Epigenetic changes in fetal hypothalamic energy regulating pathways are associated with maternal undernutrition and twinning.

Begum, Ghazala; Stevens, Adam; Smith, Emma Bolton; Connor, Kristin; Challis, John R G; Bloomfield, Frank; White, Anne.

FASEB J ; 26(4): 1694-703, 2012 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-22223754

3.

Hypothalamic AgRP neurons exert top-down control on systemic TNF-α release during endotoxemia.

Boutagouga Boudjadja, Mehdi; Culotta, Isabella; De Paula, Gabriela C; Harno, Erika; Hunter, Jenna; Cavalcanti-de-Albuquerque, João Paulo; Luckman, Simon M; Hepworth, Matthew; White, Anne; Aviello, Gabriella; D'Agostino, Giuseppe.

Curr Biol ; 32(21): 4699-4706.e4, 2022 Nov 07.

Artículo en Inglés | MEDLINE | ID: mdl-36182699

4.

Chronic glucocorticoid treatment induces hepatic lipid accumulation and hyperinsulinaemia in part through actions on AgRP neurons.

Harno, Erika; Sefton, Charlotte; Wray, Jonathan R; Allen, Tiffany-Jayne; Davies, Alison; Coll, Anthony P; White, Anne.

Sci Rep ; 11(1): 13776, 2021 07 02.

Artículo en Inglés | MEDLINE | ID: mdl-34215821

5.

Reduced Stability and pH-Dependent Activity of a Common Obesity-Linked PCSK1 Polymorphism, N221D.

Jarvela, Timothy S; Shakya, Manita; Bachor, Tomas; White, Anne; Low, Malcolm J; Lindberg, Iris.

Endocrinology ; 160(11): 2630-2645, 2019 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-31504391

6.

Metabolic Abnormalities of Chronic High-Dose Glucocorticoids Are Not Mediated by Hypothalamic AgRP in Male Mice.

Sefton, Charlotte; Davies, Alison; Allen, Tiffany-Jayne; Wray, Jonathan R; Shoop, Rosemary; Adamson, Antony; Humphreys, Neil; Coll, Anthony P; White, Anne; Harno, Erika.

Endocrinology ; 160(5): 964-978, 2019 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-30794724

7.

Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for ß-MSH and desacetyl α-MSH in energy homeostasis.

Kirwan, Peter; Kay, Richard G; Brouwers, Bas; Herranz-Pérez, Vicente; Jura, Magdalena; Larraufie, Pierre; Jerber, Julie; Pembroke, Jason; Bartels, Theresa; White, Anne; Gribble, Fiona M; Reimann, Frank; Farooqi, I Sadaf; O'Rahilly, Stephen; Merkle, Florian T.

Mol Metab ; 17: 82-97, 2018 11.

Artículo en Inglés | MEDLINE | ID: mdl-30201275

8.

Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132: interaction between AGRP83-132 and melanocortin receptors cannot be influenced by syndecan-3.

Creemers, John W M; Pritchard, Lynn E; Gyte, Amy; Le Rouzic, Philippe; Meulemans, Sandra; Wardlaw, Sharon L; Zhu, Xiaorong; Steiner, Donald F; Davies, Nicola; Armstrong, Duncan; Lawrence, Catherine B; Luckman, Simon M; Schmitz, Catherine A; Davies, Rick A; Brennand, John C; White, Anne.

Endocrinology ; 147(4): 1621-31, 2006 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-16384863

9.

Elevated Hypothalamic Glucocorticoid Levels Are Associated With Obesity and Hyperphagia in Male Mice.

Sefton, Charlotte; Harno, Erika; Davies, Alison; Small, Helen; Allen, Tiffany-Jayne; Wray, Jonathan R; Lawrence, Catherine B; Coll, Anthony P; White, Anne.

Endocrinology ; 157(11): 4257-4265, 2016 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-27649090

10.

Proopiomelanocortin-derived peptides in rat cerebrospinal fluid and hypothalamic extracts: evidence that secretion is regulated with respect to energy balance.

Pritchard, Lynn E; Oliver, Robert L; McLoughlin, Julie D; Birtles, Susan; Lawrence, Catherine B; Turnbull, Andrew V; White, Anne.

Endocrinology ; 144(3): 760-6, 2003 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-12586751

11.

Maternal undernutrition programs tissue-specific epigenetic changes in the glucocorticoid receptor in adult offspring.

Begum, Ghazala; Davies, Alison; Stevens, Adam; Oliver, Mark; Jaquiery, Anne; Challis, John; Harding, Jane; Bloomfield, Frank; White, Anne.

Endocrinology ; 154(12): 4560-9, 2013 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-24064364

12.

Epigenetic changes in the hypothalamic pro-opiomelanocortin gene: a mechanism linking maternal undernutrition to obesity in the offspring?

Stevens, Adam; Begum, Ghazala; White, Anne.

Eur J Pharmacol ; 660(1): 194-201, 2011 Jun 11.

Artículo en Inglés | MEDLINE | ID: mdl-21211530

13.

Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice.

Claret, Marc; Smith, Mark A; Knauf, Claude; Al-Qassab, Hind; Woods, Angela; Heslegrave, Amanda; Piipari, Kaisa; Emmanuel, Julian J; Colom, André; Valet, Philippe; Cani, Patrice D; Begum, Ghazala; White, Anne; Mucket, Phillip; Peters, Marco; Mizuno, Keiko; Batterham, Rachel L; Giese, K Peter; Ashworth, Alan; Burcelin, Remy; Ashford, Michael L; Carling, David; Withers, Dominic J.

Diabetes ; 60(3): 735-45, 2011 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-21266325

14.

ACTH: cellular peptide hormone synthesis and secretory pathways.

Stevens, Adam; White, Anne.

Results Probl Cell Differ ; 50: 63-84, 2010.

Artículo en Inglés | MEDLINE | ID: mdl-19888563

15.

Epigenetic changes in the hypothalamic proopiomelanocortin and glucocorticoid receptor genes in the ovine fetus after periconceptional undernutrition.

Stevens, Adam; Begum, Ghazala; Cook, Alice; Connor, Kristin; Rumball, Christopher; Oliver, Mark; Challis, John; Bloomfield, Frank; White, Anne.

Endocrinology ; 151(8): 3652-64, 2010 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-20573728

16.

Discovery and optimization of novel, non-steroidal glucocorticoid receptor modulators.

Ray, Nicholas C; Clark, Robin D; Clark, David E; Williams, Karen; Hickin, H G; Crackett, Peter H; Dyke, Hazel J; Lockey, Peter M; Wong, Melanie; Devos, René; White, Anne; Belanoff, Joseph K.

Bioorg Med Chem Lett ; 17(17): 4901-5, 2007 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-17587578

17.

Identification and optimisation of a series of substituted 5-(1H-pyrazol-3-yl)-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors.

Price, Steve; Bordogna, Walter; Bull, Richard J; Clark, David E; Crackett, Peter H; Dyke, Hazel J; Gill, Matthew; Harris, Neil V; Gorski, Julia; Lloyd, Julia; Lockey, Peter M; Mullett, Julia; Roach, Alan G; Roussel, Fabien; White, Anne B.

Bioorg Med Chem Lett ; 17(2): 370-5, 2007 Jan 15.

Artículo en Inglés | MEDLINE | ID: mdl-17095213

18.

Identification and functional characterization of Candida albicans CDC4.

Shieh, Jia-Ching; White, Anne; Cheng, Yu-Che; Rosamond, John.

J Biomed Sci ; 12(6): 913-24, 2005 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-16228290

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