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1.
BMJ Case Rep ; 16(10)2023 Oct 13.
Artículo en Inglés | MEDLINE | ID: mdl-37832974

RESUMEN

Osteitis pubis is a rare, inflammatory condition involving the pubic symphysis. While osteitis pubis has been reported following many urological procedures, including those addressing bladder outlet obstruction such as transurethral resection of the prostate, it has never been reported after holmium laser enucleation of the prostate (HoLEP). Here, we detail the clinical course of a patient found to have osteitis pubis following HoLEP. This patient presented several weeks after surgery with non-specific, persistent symptoms of groin pain and difficulty ambulating, alerting our clinicians to consider osteitis pubis which was confirmed on MRI of the pelvis. While the majority of osteitis pubis cases are managed with locally invasive techniques, our patient's symptoms were successfully managed conservatively with Foley catheter placement, oral antibiotics and close follow-up. At 9 months postoperative, the patient has reported complete resolution of symptoms and continues to be followed closely.


Asunto(s)
Artritis , Terapia por Láser , Láseres de Estado Sólido , Osteítis , Hiperplasia Prostática , Resección Transuretral de la Próstata , Masculino , Humanos , Osteítis/diagnóstico por imagen , Osteítis/etiología , Hueso Púbico/diagnóstico por imagen , Próstata , Láseres de Estado Sólido/uso terapéutico , Artritis/cirugía , Terapia por Láser/efectos adversos , Resultado del Tratamiento , Hiperplasia Prostática/cirugía
2.
BMC Infect Dis ; 19(1): 631, 2019 Jul 17.
Artículo en Inglés | MEDLINE | ID: mdl-31315565

RESUMEN

BACKGROUND: Candida arthritis is extremely rare and also represents a major challenge of diagnosis and treatment. Here we reported a rare case of recurrent arthritis caused by Candida parapsilosis. CASE PRESENTATION: A 56-year-old Chinese male suffered from recurrent pain and swelling in his right knee after several times of "small needle-knife" acupuncture and corticosteroid injection of the joint. Candida parapsilosis was cultured in his synovial fluid and identified by sequencing of its Internal Transcribed Spacer (ITS) gene. Here we present the radiological characteristics, arthroscopic pictures, and synovium pathology of this patient. Also, blood test and chemical analysis of his synovial fluid were listed as well as the ITS sequence of this Candida species identified. The patient underwent thorough arthroscopic debridement and then set on fluconazole 400 mg daily for 12 months. His symptoms resolved and no relapse was observed on the last follow-up. Additionally, a brief but comprehensive review of C. parapsilosis arthritis episodes from past to now were studied. CONCLUSION: With the detailed clinical information reported in this case and our literature review, we hope they would add to our knowledge of C. parapsilosis arthritis - its clinical settings, laboratory features, radiological characteristics, arthroscopic findings and experience of management.


Asunto(s)
Artritis/microbiología , Candida parapsilosis/patogenicidad , Candidiasis/tratamiento farmacológico , Antifúngicos/uso terapéutico , Artritis/tratamiento farmacológico , Artritis/cirugía , Candida parapsilosis/aislamiento & purificación , Desbridamiento , Fluconazol/uso terapéutico , Humanos , Rodilla/microbiología , Rodilla/patología , Masculino , Persona de Mediana Edad , Líquido Sinovial/microbiología
3.
Int J Antimicrob Agents ; 54(4): 456-462, 2019 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-31319190

RESUMEN

Carbapenemase-producing Enterobacteriaceae (CPE) are emerging multidrug-resistant bacteria responsible for invasive infections, including prosthetic joint infections (PJIs). Local administration of colistin may provide bactericidal concentrations in situ. This study evaluated the efficacy of a colistin-impregnated cement spacer, alone and in combination with systemic antibiotics, in a rabbit model of CPE-PJI. Elution of 3 MIU of colistimethate sodium (CMS) in 40 g of poly(methyl methacrylate) cement was studied in vitro. In vivo, 5 × 108 CFU of KPC-producing Klebsiella pneumoniae (colistin and meropenem MICs of 1 mg/L and 4 mg/L, respectively) were injected close to a prosthetic knee. Surgical debridement and prosthesis removal were performed 7 days later, and rabbits were assigned to six treatment groups (11-13 rabbits each): drug-free spacer; colistin-loaded spacer; colistin intramuscular (i.m.); colistin i.m. + colistin spacer; colistin i.m. + meropenem subcutaneous (s.c.); and colistin i.m. + meropenem s.c. + colistin spacer. Systemic treatment was administered at doses targeting pharmacokinetics in humans, and rabbits were euthanised 7 days later to evaluate bacterial counts in infected bones. In vitro, CMS elution was low (<0.1% at 24 h) but reached a local concentration of ≥20 mg/L (>20 × MIC). In vivo, combinations of local and systemic colistin, with or without meropenem, were the only regimens superior to the control group (P ≤ 0.05) in terms of viable bacterial counts and the proportion of rabbits with sterile bone, with no emergence of colistin-resistant strains. Colistin-loaded cement spacer in combination with systemic antibiotics were the most effective regimens in this CPE-PJI model.


Asunto(s)
Antibacterianos/administración & dosificación , Artritis/tratamiento farmacológico , Enterobacteriaceae Resistentes a los Carbapenémicos/efectos de los fármacos , Colistina/administración & dosificación , Infecciones por Klebsiella/tratamiento farmacológico , Klebsiella pneumoniae/efectos de los fármacos , Infecciones Relacionadas con Prótesis/tratamiento farmacológico , Animales , Artritis/microbiología , Artritis/cirugía , Desbridamiento , Modelos Animales de Enfermedad , Femenino , Inyecciones Intraarticulares , Inyecciones Intramusculares , Infecciones por Klebsiella/microbiología , Infecciones por Klebsiella/cirugía , Infecciones Relacionadas con Prótesis/microbiología , Infecciones Relacionadas con Prótesis/cirugía , Conejos , Resultado del Tratamiento
4.
Neuroimage Clin ; 23: 101838, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31071593

RESUMEN

Motor imagery (M.I.) training has been widely used to enhance motor behavior. To characterize the neural foundations of its rehabilitative effects in a pathological population we studied twenty-two patients with rhizarthrosis, a chronic degenerative articular disease in which thumb-to-fingers opposition becomes difficult due to increasing pain while the brain is typically intact. Before and after surgery, patients underwent behavioral tests to measure pain and motor performance and fMRI measurements of brain motor activity. After surgery, the affected hand was immobilized, and patients were enrolled in a M.I. training. The sample was split in those who had a high compliance with the program of scheduled exercises (T+, average compliance: 84%) and those with low compliance (T-, average compliance: 20%; cut-off point: 55%). We found that more intense M.I. training counteracts the adverse effects of immobilization reducing pain and expediting motor recovery. fMRI data from the post-surgery session showed that T+ patients had decreased brain activation in the premotor cortex and the supplementary motor area (SMA); meanwhile, for the same movements, the T- patients exhibited a reversed pattern. Furthermore, in the post-surgery fMRI session, pain intensity was correlated with activity in the ipsilateral precentral gyrus and, notably, in the insular cortex, a node of the pain matrix. These findings indicate that the motor simulations of M.I. have a facilitative effect on recovery by cortical plasticity mechanisms and optimization of motor control, thereby establishing the rationale for incorporating the systematic use of M.I. into standard rehabilitation for the management of post-immobilization syndromes characteristic of hand surgery.


Asunto(s)
Mano/fisiología , Imágenes en Psicoterapia/tendencias , Imaginación/fisiología , Imagen por Resonancia Magnética/tendencias , Actividad Motora/fisiología , Cuidados Posoperatorios/tendencias , Anciano , Artritis/psicología , Artritis/rehabilitación , Artritis/cirugía , Estudios de Cohortes , Femenino , Mano/cirugía , Humanos , Imágenes en Psicoterapia/métodos , Estudios Longitudinales , Masculino , Persona de Mediana Edad , Cuidados Posoperatorios/métodos , Cuidados Posoperatorios/psicología , Pulgar/fisiología , Pulgar/cirugía
5.
Foot Ankle Int ; 40(1): 24-33, 2019 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-30203667

RESUMEN

BACKGROUND:: Ankle arthritis is a highly limiting pathology that causes pain and functional limitation with subsequent deterioration of quality of life. With recent advances in surgical instrumentation and techniques, prosthetic replacement of the ankle has proven to be a valid alternative to arthrodesis with comparable outcomes. The purpose of this study was to evaluate clinical and radiological findings in a transfibular total ankle replacement with follow-up of at least 2 years. METHODS:: This prospective study included 89 patients who underwent transfibular total ankle arthroplasty from May 2013 to February 2016. The mean age was 53.2 ± 13.5 years. All patients were followed for at least 24 months postoperatively with an average follow-up of 42.0 ± 23.5 months. Patients were assessed clinically and radiographically preoperatively and at 6, 12, and 24 months postoperatively. RESULTS:: At 24 months postoperatively, patients demonstrated statistically significant improvement in the American Orthopaedic Foot & Ankle Society (AOFAS) Ankle Hindfoot Score from 33.8 ± 14.3 to 88.5 ± 6.6 ( P < .001), visual analog scale (VAS) from 80.5 ± 17.0 to 14.1 ± 9.2 ( P < .001), and Short Form-12 Physical and Mental Composite Scores from 29.9 ± 6.7 and 43.3 ± 8.6 to 47.0 ± 7.6 and 53.3 ± 8.1, respectively ( P < .001). In addition, ankle dorsiflexion and plantarflexion improved from 6.2 ± 5.5 and 9.6 ± 5.8 degrees to 24.2 ± 7.9 and 18.1 ± 7.6 degrees, respectively ( P < .001). Radiographically, patients demonstrated maintained neutral alignment of the ankle at 24 months. No patient demonstrated any radiographic evidence of tibial or talar lucency at final follow-up. Seven patients underwent reoperation for removal of symptomatic hardware (6 fibular plates, 1 syndesmotic screw); 2 patients experienced delayed wound healing. The first one was treated with plate removal and flap coverage. The second one required fibular plate removal. One patient developed a postoperative prosthetic infection requiring operative debridement, removal of implants, and placement of an antibiotic spacer. CONCLUSION:: This study found that transfibular total ankle replacement was a safe and effective option for patients with ankle arthritis resulting in improvements in patient-reported outcomes, range of motion, and radiographic parameters. However, further studies are required to determine the mid- and long-term performance of these implants. LEVEL OF EVIDENCE:: Level IV, case series.


Asunto(s)
Articulación del Tobillo/cirugía , Artritis/cirugía , Artroplastia de Reemplazo de Tobillo , Prótesis Articulares , Adulto , Anciano , Articulación del Tobillo/diagnóstico por imagen , Artroplastia de Reemplazo de Tobillo/métodos , Tornillos Óseos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Calidad de Vida , Radiografía , Resultado del Tratamiento
6.
Knee ; 24(2): 434-438, 2017 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-28189408

RESUMEN

BACKGROUND: The medial pivot total knee prosthesis with alumina ceramic femoral components was introduced to reproduce physiological knee kinematics and reduce polyethylene wear. The five-year clinical outcomes of alumina medial pivot total knee arthroplasties (TKA) have previously been reported. The purpose of this study was to provide the longer-term clinical results at a minimum follow-up of 10years. METHODS: The clinical results of 70 alumina medial pivot TKA in 51 consecutive patients, with a minimum follow-up period of 10years, were evaluated. RESULTS: Mean follow-up was 11.8years (range 10 to 13). Alumina medial pivot TKAs improved the patients' Knee Society knee scores, function scores, and postoperative ranges of motion compared with their pre-operative statuses (P<0.05 for each). Revision surgery was required in one knee due to a postoperative fracture of the tibial plateau after a fall that occurred two years postoperatively. Osteolysis and femoral component loosening was identified in one case after the initial five-year time point of analysis. The survival rate was 99.1% at 10years. CONCLUSIONS: This study demonstrated excellent clinical results for patients receiving the alumina medial pivot prosthesis at a minimum follow-up period of 10years.


Asunto(s)
Artritis/cirugía , Artroplastia de Reemplazo de Rodilla/instrumentación , Prótesis de la Rodilla , Anciano , Anciano de 80 o más Años , Óxido de Aluminio , Materiales Biocompatibles , Cerámica , Fémur/cirugía , Estudios de Seguimiento , Humanos , Articulación de la Rodilla/cirugía , Persona de Mediana Edad , Polietileno , Diseño de Prótesis , Reoperación , Tibia/cirugía
7.
Acta Chir Orthop Traumatol Cech ; 83(5): 348-350, 2016.
Artículo en Checo | MEDLINE | ID: mdl-28102811

RESUMEN

PURPOSE OF THE STUDY Total knee arthroplasty is commonly used procedure with advanced stage arthritis which causes extensive blood loss intraoperatively and postoperatively. Purpose of this study is to show the effectiveness of sealing of femoral tunnel with bone grafting in preventing blood loss. MATERIAL AND METHODS 288 patients with primary bicompartmental knee arthroplasty who were operated in between April 2012 and June 2015 are retrospectively studied. Two groups are formed according to sealing of femoral tunnel with autologous bone graft or not. Group 1 was the plugged group with 192 patients and group 2 was the unplugged group with 96 patients. Operation time, arthrotomy method, anticoagulant therapy, postoperative care were similar in between two groups.'Independent sample t-test' is used to compare two groups as statistical method. RESULTS Postoperative lowest hemoglobin levels are higher in plugged group (p < 0.001). Drain outputs are much less than unplugged group (p < 0.001). There is no statistically significant difference between amount of given erythrocyte suspensions. DISCUSSION In the literature there are many attempts to reduce blood loss and allogenic blood transfusion. Some systemic or local usage of medical therapies, mechanical interventions such as cold application or intraoperative fibrin sealers are some of them. There are a few studies favoring usage of plugs and a few do not. Our findings showed less blood loss with usage of autologous bone grafting but did not significantly affect the blood transfusion amount. CONCLUSION Autologous bone grafting is a free to use, non-time consuming and an effective method to reduce blood loss. Key words: knee arthroplasty, plug, sealing of femoral tunnel, blood loss.


Asunto(s)
Artritis/cirugía , Artroplastia de Reemplazo de Rodilla/efectos adversos , Pérdida de Sangre Quirúrgica/prevención & control , Trasplante Óseo/métodos , Anticoagulantes/uso terapéutico , Artroplastia de Reemplazo de Rodilla/métodos , Transfusión de Sangre Autóloga/estadística & datos numéricos , Trasplante Óseo/estadística & datos numéricos , Humanos , Tempo Operativo , Cuidados Posoperatorios , Estudios Retrospectivos , Trasplante Autólogo , Resultado del Tratamiento
8.
Diagn Microbiol Infect Dis ; 76(1): 93-8, 2013 May.
Artículo en Inglés | MEDLINE | ID: mdl-23541692

RESUMEN

Linezolid may be an interesting alternative for prosthetic joint infection (PJI) due to its bioavailability and its antimicrobial spectrum. However, experience in this setting is scarce. The aim of the study was to assess linezolid's clinical and microbiological efficacy, and also its tolerance. This was a prospective, multicenter, open-label, non-comparative study of 25 patients with late-chronic PJI caused by Gram-positive bacteria managed with a two-step exchange procedure plus 6 weeks of linezolid. Twenty-two (88%) patients tolerated linezolid without major adverse effects, although a global decrease in the platelet count was observed. Three patients were withdrawn because of major toxicity, which reversed after linezolid stoppage. Among patients who completed treatment, 19 (86%) demonstrated clinical and microbiological cure. Two patients presented with clinical and microbiological failure, and one showed clinical cure and microbiological failure. In conclusion, linezolid showed good results in chronic PJI managed with a two-step exchange procedure. Tolerance seems acceptable, though close surveillance is required.


Asunto(s)
Acetamidas/uso terapéutico , Antibacterianos/uso terapéutico , Artritis/microbiología , Bacterias Grampositivas/aislamiento & purificación , Oxazolidinonas/uso terapéutico , Infecciones Relacionadas con Prótesis/tratamiento farmacológico , Acetamidas/farmacocinética , Anciano , Anciano de 80 o más Años , Antibacterianos/farmacocinética , Artritis/cirugía , Femenino , Bacterias Grampositivas/efectos de los fármacos , Humanos , Linezolid , Masculino , Persona de Mediana Edad , Oxazolidinonas/farmacocinética , Estudios Prospectivos , Infecciones Relacionadas con Prótesis/microbiología , Resultado del Tratamiento
9.
Nanomedicine (Lond) ; 8(12): 1969-83, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23534832

RESUMEN

AIM: To develop a clinically applicable MRI technique for tracking stem cells in matrix-associated stem-cell implants, using the US FDA-approved iron supplement ferumoxytol. MATERIALS & METHODS: Ferumoxytol-labeling of adipose-derived stem cells (ADSCs) was optimized in vitro. A total of 11 rats with osteochondral defects of both femurs were implanted with ferumoxytol- or ferumoxides-labeled or unlabeled ADSCs, and underwent MRI up to 4 weeks post matrix-associated stem-cell implant. The signal-to-noise ratio of different matrix-associated stem-cell implant was compared with t-tests and correlated with histopathology. RESULTS: An incubation concentration of 500 µg iron/ml ferumoxytol and 10 µg/ml protamine sulfate led to significant cellular iron uptake, T2 signal effects and unimpaired ADSC viability. In vivo, ferumoxytol- and ferumoxides-labeled ADSCs demonstrated significantly lower signal-to-noise ratio values compared with unlabeled controls (p < 0.01). Histopathology confirmed engraftment of labeled ADSCs, with slow dilution of the iron label over time. CONCLUSION: Ferumoxytol can be used for in vivo tracking of stem cells with MRI.


Asunto(s)
Rastreo Celular/métodos , Medios de Contraste/análisis , Óxido Ferrosoférrico/análisis , Imagen por Resonancia Magnética/métodos , Trasplante de Células Madre , Células Madre/citología , Animales , Artritis/patología , Artritis/cirugía , Células Cultivadas , Femenino , Fémur/patología , Fémur/cirugía , Articulaciones/patología , Articulaciones/cirugía , Soluciones para Nutrición Parenteral/análisis , Ratas , Ratas Desnudas
10.
J Arthroplasty ; 27(7): 1414.e1-4, 2012 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-22088780

RESUMEN

Skeletal tuberculosis (TB) frequently masquerades as more common etiologies and can be difficult to diagnose. We describe a case of TB knee arthritis in a young Haitian-born woman in whom the diagnosis was not initially suspected, resulting in treatment with total knee arthroplasty that subsequently failed. A long course of medical and surgical therapies was then necessary to treat this patient. Issues in the diagnosis and management of TB in the native and prosthetic knee joint are presented.


Asunto(s)
Artritis/microbiología , Artritis/cirugía , Artroplastia de Reemplazo de Rodilla , Infecciones Relacionadas con Prótesis/diagnóstico , Tuberculosis Osteoarticular/diagnóstico , Adulto , Antituberculosos/uso terapéutico , Diagnóstico Diferencial , Femenino , Humanos , Articulación de la Rodilla/diagnóstico por imagen , Articulación de la Rodilla/microbiología , Articulación de la Rodilla/cirugía , Mycobacterium tuberculosis/aislamiento & purificación , Infecciones Relacionadas con Prótesis/tratamiento farmacológico , Infecciones Relacionadas con Prótesis/cirugía , Radiografía , Reoperación , Resultado del Tratamiento , Tuberculosis Osteoarticular/tratamiento farmacológico , Tuberculosis Osteoarticular/cirugía
11.
Scand J Infect Dis ; 42(11-12): 890-5, 2010 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-20608769

RESUMEN

Candida prosthetic joint infections are considered to be rare. We retrospectively studied patients treated for Candida prosthetic infections between 1 January 1995 and 31 December 2007 in our infectious diseases department, a tertiary referral centre. We identified 7 patients, 4 with knee and 3 with hip prosthetic infections. The most frequent fungal agent was Candida albicans (4 cases), followed by Candida parapsilosis (2 cases) and Candida guillermondii (1 case). All the patients received antifungal treatment for a prolonged period. Five patients had their prosthesis removed and 3 had reimplantation, 1 patient was treated with debridement and prosthetic retention, and the last patient refused surgery. The mean follow-up time was 2.5 y. At the last evaluation, 3 patients were considered as cured, 3 patients presented a secondary bacterial infection leading to amputation for 2 of them, and 1 patient died from heart failure. During Candida prosthetic joint infections, the epidemiological characteristics and the location of the prosthesis are very similar to bacterial prosthetic infections. The benchmark antifungal therapies remain amphotericin B and/or fluconazole.


Asunto(s)
Artritis/diagnóstico , Candida/aislamiento & purificación , Candidiasis/diagnóstico , Infecciones Relacionadas con Prótesis/diagnóstico , Anciano , Anciano de 80 o más Años , Antifúngicos/uso terapéutico , Artritis/tratamiento farmacológico , Artritis/microbiología , Artritis/cirugía , Candida/clasificación , Candidiasis/tratamiento farmacológico , Candidiasis/microbiología , Candidiasis/cirugía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Infecciones Relacionadas con Prótesis/tratamiento farmacológico , Infecciones Relacionadas con Prótesis/microbiología , Infecciones Relacionadas con Prótesis/cirugía , Resultado del Tratamiento
12.
Clin Orthop Relat Res ; 468(2): 605-12, 2010 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-19568823

RESUMEN

UNLABELLED: Osteoarticular tuberculosis (TB) in the hip and other joints is increasing and patients in developing countries commonly present with advanced joint destruction. We asked whether TB is reactivated after THA in these patients. We retrospectively reviewed 12 patients with an average age of 45 years who had advanced stages of hip destruction secondary to mycobacterium TB and who were treated with primary THA and prescribed perioperative antituberculous medication for 12 to 18 months postoperatively. Diagnosis in all these patients was confirmed by histopathology and culture. The minimum followup was 25 months (average, 41 months; range, 25-58 months). We observed no reactivation of TB in 11 patients who had Harris hip scores ranging from 86 to 97. One patient who postoperatively did not comply with the antituberculous chemotherapy had reactivation and superimposed infection through a nonhealing sinus tract; that patient underwent component removal and resection arthroplasty. When the infected tissue can be débrided and adequate antituberculous therapy is instituted the outcome of joint arthroplasty may not be adversely affected. THA in the tuberculous hip has a low risk of reactivation and produces good functional results. LEVEL OF EVIDENCE: Level IV, therapeutic case series (no, or historical control group). See the Guidelines for Authors for a complete description of levels of evidence.


Asunto(s)
Artritis/cirugía , Artroplastia de Reemplazo de Cadera , Articulación de la Cadera/cirugía , Tuberculosis Osteoarticular/cirugía , Adulto , Antituberculosos/uso terapéutico , Artritis/diagnóstico por imagen , Artritis/microbiología , Artritis/fisiopatología , Artroplastia de Reemplazo de Cadera/efectos adversos , Terapia Combinada , Desbridamiento , Femenino , Articulación de la Cadera/diagnóstico por imagen , Articulación de la Cadera/microbiología , Articulación de la Cadera/fisiopatología , Humanos , Imagen por Resonancia Magnética , Masculino , Cumplimiento de la Medicación , Persona de Mediana Edad , Radiografía , Recuperación de la Función , Reoperación , Estudios Retrospectivos , Índice de Severidad de la Enfermedad , Resultado del Tratamiento , Tuberculosis Osteoarticular/diagnóstico por imagen , Tuberculosis Osteoarticular/microbiología , Tuberculosis Osteoarticular/fisiopatología
13.
J Knee Surg ; 21(4): 275-8, 2008 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-18979928

RESUMEN

Patients undergoing total knee arthroplasty (TKA) often experience a difficult recovery due to severe postoperative pain. Using a multimodal pain management protocol, a blinded, randomized, placebo-controlled study was designed to evaluate the efficacy of patient-selected music on reducing perceived pain. Thirty patients undergoing primary unilateral TKA were enrolled and randomized into the music group (15 patients) or the control group (15 patients). Postoperative pain scores, assessed with the visual analog scale, indicated the music group experienced less pain at 3 and 24 hours postoperatively than did the nonmusic group (at 3 hours: 1.47+/-1.39 versus 3.87+/-3.44, P=.01; at 24 hours: 2.41+/-1.67 versus 4.03+/-2.89, P=.04). Intraoperative music provides an inexpensive nonpharmacological option to further reduce postoperative pain.


Asunto(s)
Artritis/cirugía , Artroplastia de Reemplazo de Rodilla/efectos adversos , Musicoterapia , Dolor Postoperatorio/etiología , Dolor Postoperatorio/prevención & control , Anciano , Método Doble Ciego , Femenino , Estudios de Seguimiento , Humanos , Cuidados Intraoperatorios , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Satisfacción del Paciente , Estudios Prospectivos , Resultado del Tratamiento
14.
J Biomed Mater Res B Appl Biomater ; 86(2): 460-5, 2008 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-18335431

RESUMEN

Silicone spacers have been in use as replacement joints in the human hand for over 30 years. Since they were first used there has been a number of designs all of which have had problems with fracture. This may be due to a defect in the material caused during implantation, or by bony intrusions within the arthritic hand after implantation. The aim of this research was to investigate the effect of the environment on the mechanical properties of medical grade silicones used for human implantation. The materials were subjected to static tensile testing after various forms of ageing. The environmental conditions included temperatures of 37 and 80 degrees C and the environments of Ringer's solution, distilled water, and air. The environmental conditions employed resulted in reduced mechanical strength with ageing time of the silicones. This research supports the view that failure of silicone implants in the hand could be partly attributed to the effects of environmental ageing of the material.


Asunto(s)
Artritis/cirugía , Artroplastia para la Sustitución de Dedos/métodos , Materiales Biocompatibles , Mano/cirugía , Ensayo de Materiales , Siliconas/uso terapéutico , Aire , Ambiente , Humanos , Soluciones Isotónicas , Mecánica , Solución de Ringer , Siliconas/normas , Temperatura , Agua
15.
Clin Orthop Relat Res ; 466(2): 317-23, 2008 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-18196412

RESUMEN

UNLABELLED: THA in patients younger than 30 years old presents challenges: the initial technical challenge relates to the initial disease that often causes deformities making reconstruction difficult, while the long-term challenge is wear and subsequent osteolysis and component loosening. Ceramic-on-ceramic prostheses may represent a valuable option to reduce wear. We retrospectively studied 101 patients (132 hips) with ceramic-on-ceramic prostheses implanted from 1977 to 2004. As a result of the long span of time, different implant designs and modes of fixation were used. The average age of the patients was 23.4+/-5 years (range, 13-30 years), and the main indication for THA was femoral head necrosis. The minimum followup was 1 year (mean, 6.9 years; range, 1-26.5 years). We documented 17 revisions (13%) for aseptic loosening. Twelve were for isolated acetabular loosening, two for isolated femoral loosening, and three for loosening of both components. Survivorship was 82.1% at 10 years and 72.4% at 15 years. Inferior survivorship was observed for THA performed after secondary arthritis related to slipped capital epiphysis or trauma. Limited osteolysis was observed in one hip. The main limiting factor in this series was the fixation of the acetabular component. However, improvements in the design and in the mode of fixation of this component should enhance long-term results. LEVEL OF EVIDENCE: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.


Asunto(s)
Óxido de Aluminio , Artroplastia de Reemplazo de Cadera/instrumentación , Artroplastia de Reemplazo de Cadera/métodos , Necrosis de la Cabeza Femoral/cirugía , Prótesis de Cadera , Acetábulo/patología , Adolescente , Adulto , Factores de Edad , Artritis/patología , Artritis/cirugía , Artroplastia de Reemplazo de Cadera/efectos adversos , Femenino , Necrosis de la Cabeza Femoral/patología , Estudios de Seguimiento , Humanos , Estimación de Kaplan-Meier , Masculino , Falla de Prótesis , Reoperación/estadística & datos numéricos , Estudios Retrospectivos , Resultado del Tratamiento
16.
J Bone Joint Surg Am ; 89(4): 727-34, 2007 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-17403793

RESUMEN

BACKGROUND: Biologic glenoid resurfacing was developed in 1988 as an alternative to total shoulder arthroplasty in selected (usually younger) patients with primary, posttraumatic, or postreconstructive glenohumeral arthritis. A variety of biologic surfaces, including anterior capsule, autogenous fascia lata, and Achilles tendon allograft, have been combined with a humeral hemiarthroplasty. METHODS: From November 1988 to November 2003, thirty-four patients (thirty-six shoulders) who were managed with biologic glenoid resurfacing and humeral head replacement either with cement (ten shoulders) or without cement (twenty-six shoulders) were followed prospectively. The study group included thirty men and four women with an average age of fifty-one years. The diagnoses included primary glenohumeral osteoarthritis (eighteen shoulders), postreconstructive arthritis (twelve), posttraumatic arthritis (five), and osteonecrosis (one). Anterior capsule was used for seven shoulders, autogenous fascia lata for eleven, and Achilles tendon allograft for eighteen. All shoulders were assessed clinically and with serial radiographs. RESULTS: The mean American Shoulder and Elbow Surgeons score was 39 points preoperatively and 91 points at the time of the most recent follow-up. According to Neer's criteria, the result was excellent for eighteen shoulders, satisfactory for thirteen, and unsatisfactory for five. Glenoid erosion averaged 7.2 mm and appeared to stabilize at five years. There were no revisions for humeral component loosening. Complications included infection (two patients), instability (three patients), brachial plexitis (one patient), and deep-vein thrombosis (one patient). Factors that appeared to be associated with unsatisfactory results were the use of capsular tissue as the resurfacing material and infection. CONCLUSIONS: Biologic resurfacing of the glenoid can provide pain relief similar to total shoulder arthroplasty. It allows selected younger patients to maintain an active lifestyle, including weight-lifting and manual work, without the risk of polyethylene wear. On the basis of this and previous reviews, we currently recommend Achilles tendon allograft as the preferred resurfacing material when this option is chosen. LEVEL OF EVIDENCE: Therapeutic Level IV. See Instructions to Authors for a complete description of levels of evidence.


Asunto(s)
Artritis/cirugía , Artroplastia de Reemplazo/métodos , Articulación del Hombro/cirugía , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Factores de Tiempo , Resultado del Tratamiento
17.
J Bone Joint Surg Br ; 88(7): 877-82, 2006 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-16798988

RESUMEN

A modular layered acetabular component (metal-polyethylene-ceramic) was developed in Japan for use in alumina ceramic-on-ceramic total hip replacement. Between May 1999 and July 2000, we performed 35 alumina ceramic-on-ceramic total hip replacements in 30 consecutive patients, using this layered component and evaluated the clinical and radiological results over a mean follow-up of 5.8 years (5 to 6.5). A total of six hips underwent revision, one for infection, two for dislocation with loosening of the acetabular component, two for alumina liner fractures and one for component dissociation with pelvic osteolysis. There were no fractures of the ceramic heads, and no loosening of the femoral or acetabular component in the unrevised hips was seen at final follow-up. Osteolysis was not observed in any of the unrevised hips. The survivorship analysis at six years after surgery was 83%. The layered acetabular component in our experience, has poor durability because of unexpected mechanical failures including alumina liner fracture and component dissociation.


Asunto(s)
Acetábulo/cirugía , Óxido de Aluminio , Artritis/cirugía , Artroplastia de Reemplazo de Cadera/instrumentación , Cerámica , Acetábulo/diagnóstico por imagen , Anciano , Anciano de 80 o más Años , Artritis/diagnóstico por imagen , Femenino , Articulación de la Cadera/diagnóstico por imagen , Articulación de la Cadera/cirugía , Humanos , Persona de Mediana Edad , Osteoartritis de la Cadera/diagnóstico por imagen , Osteoartritis de la Cadera/cirugía , Complicaciones Posoperatorias , Diseño de Prótesis , Falla de Prótesis , Radiografía , Reoperación , Análisis de Supervivencia , Resultado del Tratamiento
18.
J Bone Joint Surg Am ; 88(6): 1223-30, 2006 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-16757754

RESUMEN

BACKGROUND: We are not aware of any previous study that has examined predictive factors for blood transfusion after shoulder arthroplasty. We analyzed the association between clinical factors and the need for postoperative blood transfusion and documented the use and waste of predonated blood in a group of patients managed with shoulder arthroplasty. METHODS: A retrospective study of 119 patients who underwent 124 shoulder arthroplasties (including eighty-seven primary uncomplicated total shoulder arthroplasties, twenty-seven revision or complicated primary total shoulder arthroplasties, and ten hemiarthroplasties) from 2001 to 2004 was performed. Logistic regression analysis was conducted to determine which clinical variables were predictive of transfusion. RESULTS: A postoperative transfusion was received after thirty-one arthroplasties (25%). The strongest predictor of blood transfusion after shoulder arthroplasty was the preoperative hemoglobin level (likelihood ratio test = 37.8, p < 0.0001). Patients with a preoperative hemoglobin level of between 110 and 130 g/L had a five times greater estimated risk of transfusion than those with a level of >130 g/L (p < 0.001). Gender, body mass index, preoperative diagnosis, comorbid conditions, use of anticoagulants or aspirin, autologous predonation status, type of anesthesia, operative time, and decrease in hemoglobin or hematocrit were not predictors of blood transfusion. One hundred and two (78%) of the 131 predonated autologous units were discarded. Patients with a preoperative hemoglobin level of >130 g/L had the highest percentage of wasted units (90%; fifty-five of sixty-one). Preoperative autologous blood donation did not eliminate the risk of allogeneic blood transfusion in autologous donors. CONCLUSIONS: The preoperative hemoglobin level is the strongest predictor of blood transfusion after shoulder surgery, and individuals with a preoperative hemoglobin level of <110 g/L have the highest risk of transfusion. On the basis of these findings, we do not recommend autologous predonation for individuals with a preoperative hemoglobin level of >130 g/L, to avoid unnecessary expense and waste.


Asunto(s)
Artritis/cirugía , Artroplastia , Transfusión de Sangre Autóloga/estadística & datos numéricos , Osteonecrosis/cirugía , Articulación del Hombro , Adulto , Anciano , Anciano de 80 o más Años , Artritis/sangre , Donantes de Sangre , Femenino , Hemoglobinas/metabolismo , Humanos , Masculino , Persona de Mediana Edad , Osteonecrosis/sangre , Valor Predictivo de las Pruebas , Estudios Retrospectivos
19.
Clin Orthop Relat Res ; 451: 107-12, 2006 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-16702921

RESUMEN

The unicompartmental knee arthroplasty continues to gain popularity as a viable treatment option for disease isolated to one compartment. It has been reported to provide decreased perioperative morbidity, faster recovery, and excellent long- term survival. We hypothesized that the unicompartmental knee arthroplasty is durable enough to benefit octogenarians, and may be a viable alternative to total knee arthroplasty as the definitive treatment of localized arthritis in this age group. From 1978 to 1990, 28 consecutive patients (38 knees) 80 years or older had unicompartmental knee arthroplasties. Knee Society knee and function scores improved at an average of 4 years followup (range, 2-9 years). Family members reported 90% patient satisfaction regarding expectations and desire to have the surgery again. The mean postoperative survival was 11.9 years, and only two of the 38 knees (5%) required surgical intervention. At final followup, 25 patients had died with all but one patient having the index unicompartmental knee arthroplasty in place and functioning well. Of the three living patients, one required surgery for femoral component fracture 10 years after the index procedure. The unicompartmental knee arthroplasty can be expected to provide reliable and durable results in certain octogenarians, and should be regarded as a definitive treatment option in appropriated selected patients of this age group.


Asunto(s)
Artritis/cirugía , Artroplastia de Reemplazo de Rodilla , Prótesis de la Rodilla , Factores de Edad , Anciano de 80 o más Años , Artritis/mortalidad , Femenino , Estudios de Seguimiento , Humanos , Masculino , Satisfacción del Paciente , Reoperación , Reproducibilidad de los Resultados , Estudios Retrospectivos , Tasa de Supervivencia , Resultado del Tratamiento
20.
J Bone Joint Surg Br ; 88(4): 509-14, 2006 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-16567787

RESUMEN

There have been few reports in the literature of total elbow arthroplasty extending beyond 10 to 15 years. We reviewed 40 patients (41 elbows) with a mean age of 56 years (19 to 83) who had undergone a Coonrad/Coonrad-Morrey elbow arthroplasty by one surgeon for various diagnoses between 1974 and 1994. Surgical selection excluded patients with previous elbow infection or who refused to accept a sedentary level of elbow activity postoperatively. Objective data were collected from charts, radiographs, clinical photographs and supplemented by the referring orthopaedic surgeons' records and radiographs if health or distance prevented a patient from returning for final review. Subjective outcome was defined by patient satisfaction. Of the 41 elbows, 21 were functional between 10 and 14 years after operation, ten between 15 and 19 years and ten between 20 and 31 years. There were 14 complications and 13 revisions, but no cases of acute infection, or permanent removal of any implant.


Asunto(s)
Artroplastia de Reemplazo/métodos , Articulación del Codo/cirugía , Prótesis Articulares , Adulto , Anciano , Anciano de 80 o más Años , Artritis/mortalidad , Artritis/cirugía , Artroplastia de Reemplazo/efectos adversos , Artroplastia de Reemplazo/mortalidad , Articulación del Codo/diagnóstico por imagen , Articulación del Codo/fisiopatología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Falla de Prótesis , Radiografía , Reoperación , Estudios Retrospectivos , Análisis de Supervivencia
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