RESUMEN
OBJECTIVE: To study the alkaloids from Corydalis impatiens. METHODS: The alkaloids were isolated and purified by chromatography and their structures were identified by spectral data and others methods. RESULTS: Seven alkaloids were isolated and identified as bicuculline(1), ochotensine(2), ochotensimine(3), ochrobirine(4), tetrahydrothalifendine(5), norochotensimine(6), N-methylactinodaphnine(7). CONCLUSION: All these compounds are isolated from this plant for the first time.
Asunto(s)
Alcaloides/aislamiento & purificación , Corydalis/química , Dioxolanos/aislamiento & purificación , Plantas Medicinales/química , Alcaloides/química , Bicuculina/química , Bicuculina/aislamiento & purificación , Cromatografía en Capa Delgada , Dioxolanos/química , Estructura Molecular , Extractos Vegetales/química , Extractos Vegetales/aislamiento & purificación , Raíces de Plantas/químicaRESUMEN
A new alkaloid, chaerophylline (1), together with known alkaloids (-)-corypalmine, berberine chloride, (-)-isocorypalmine, (-)-corydalmine and (+)-bicuculline have been isolated from the crude base fraction of Corydalis chaerophylla. The crude base fractions of Corydalis longipes gave a new alkaloid, longicine (4), together with known alkaloids (+/-)-alpha-hydrastine, (+/-)-beta-hydrastine, N-methylhydrasteine hydroxylactam, 1-methoxyberberine chloride and berberinium hydroxide. These alkaloids are reported for the first time from the above species and their structures were established by chemical and spectroscopic evidence.
Asunto(s)
Alcaloides/química , Corydalis/química , Extractos Vegetales/química , Alcaloides/aislamiento & purificación , Berberina/análogos & derivados , Berberina/química , Bicuculina/química , Compuestos Heterocíclicos de 4 o más Anillos/química , Espectroscopía de Resonancia Magnética , Estructura MolecularRESUMEN
The isoquinoline alkaloids protopine, cryptopine, sinactine, stylopine, bicuculline, adlumine, parfumine, fumariline, fumarophycine, fumaritine, dihydrofumariline, parfumidine and dihydrosanguinarine have been determined and identified by gas chromatography-mass spectrometry in Fumaria agraria, F. bastardii, F. capreolata, F. sepium, F. densiflora, F. faurei, F. officinalis subsp. officinalis, F. parviflora, F. petteri subsp. calcarata and F. macrosepala. The chemotaxonomic significance of the results is discussed.