RESUMEN
Revealed in the wake of balneotherapy at the Truskavets health-resort were two opposite types of changes--those in the level of uriacidemia and in the content of theophylline-sensitive lymphocytes that are probably caused by central and peripheral effects of uric acid. In this setting, parameters characterizing the phagocytic link of immunity and unspecific defense are noted to change unidirectionally, in other words, they remain unaffected by changes in uriacidemia.
Asunto(s)
Balneología , Hiperuricemia/inmunología , Fagocitosis/inmunología , Ácido Úrico , Colonias de Salud , Humanos , Hiperuricemia/sangre , Hiperuricemia/etiología , Hiperuricemia/terapia , Inmunidad Celular/inmunología , Aguas Minerales , Pielonefritis/complicaciones , Pielonefritis/inmunología , Linfocitos T/inmunología , Ucrania , Ácido Úrico/sangre , Ácido Úrico/metabolismo , Cálculos Urinarios/complicaciones , Cálculos Urinarios/inmunologíaRESUMEN
The authors present a technique of treating chronic calculous pyelonephritis with laser radiation and sinusoidal modulated currents which promotes a complete elimination of the calculus fragments in 100, 70 and 50% of the patients in the stone size 0.2-0.5 cm, 0.5-0.7 cm and > 7 cm, respectively. This combined therapy had also antiinflammatory, and immunity-stimulating effects.
Asunto(s)
Terapia por Estimulación Eléctrica/métodos , Terapia por Láser , Pielonefritis/rehabilitación , Cálculos Urinarios/rehabilitación , Formación de Anticuerpos/efectos de la radiación , Enfermedad Crónica , Terapia Combinada , Electrólitos/sangre , Electrólitos/efectos de la radiación , Humanos , Inmunidad Celular/efectos de la radiación , Inmunoglobulinas/sangre , Inmunoglobulinas/efectos de la radiación , Pielonefritis/sangre , Pielonefritis/inmunología , Cálculos Urinarios/sangre , Cálculos Urinarios/inmunologíaRESUMEN
51 patients with urolithiasis complicated by pyelonephritis in the active phase of inflammation were studied for the condition of local immunity by determining the urine content of secretory immunoglobulin A (SIgA) under conditions of combined treatment with making use of phlogenzyme, a drug of II-generation systemic enzymotherapy (SE). Recordable in this patients population was a marked increase in the urine level of SIgA. Incorporation in a combined treatment of phlogenzyme results in normalizing the status of the urinary system local immunity. Evidence has been obtained on the lack of parallelism in the dynamics between the serum IgA content and urine concentration of SIgA, which fact suggests independence of local immunity. Our theory is that an appreciable increase in the urine level of SIgA in patients with urolithiasis concurrent with pyelonephritis may have an important part to play in the genesis of nephrolithiasis.