RESUMEN
Cerumen is a naturally occurring, normally extruded product of the external auditory canal. It is usually asymptomatic, but when it becomes impacted it can cause complications such as hearing loss, pain, or dizziness. It also can interfere with examination of the tympanic membrane. Depending on available equipment, physician skill, and patient circumstances, treatment options for cerumen impaction include watchful waiting, manual removal, the use of ceruminolytic agents, and irrigation with or without ceruminolytic pretreatment. The overall quality of the evidence on treatment is limited. Referral to an otolaryngologist for further evaluation is indicated if treatment with a ceruminolytic agent followed by irrigation is ineffective, if manual removal is not possible, if the patient develops severe pain or has vertigo during irrigation, or if hearing loss is still present after cerumen has been removed. The use of cotton swabs and ear candles should be avoided.
Asunto(s)
Cerumen , Conducto Auditivo Externo , Pérdida Auditiva/prevención & control , Cerumen/metabolismo , Legrado/métodos , Medicina Familiar y Comunitaria/normas , Humanos , Derivación y Consulta , Tensoactivos/administración & dosificación , Irrigación Terapéutica/métodosRESUMEN
Here we provided the first genetic evidence for an association between the degree of apocrine colostrum secretion and human earwax type. Genotyping at the earwax-type locus, rs17822931 within the ABCC11 gene, revealed that 155 of 225 Japanese women were dry-type and 70 wet-type. Frequency of women without colostrum among dry-type women was significantly higher than that among wet-type women (P<0.0002), and the measurable colostrum volume in dry-type women was significantly smaller than in wet-type women (P=0.0341).
Asunto(s)
Cerumen/metabolismo , Calostro/metabolismo , Transportadoras de Casetes de Unión a ATP/genética , Pueblo Asiatico , Femenino , Humanos , Polimorfismo GenéticoAsunto(s)
Benzocaína/uso terapéutico , Cerumen , Clorobencenos/uso terapéutico , Clorobutanol/uso terapéutico , Enfermedades del Oído/tratamiento farmacológico , Aceites/uso terapéutico , Bicarbonato de Sodio/uso terapéutico , Arachis , Cerumen/metabolismo , Método Doble Ciego , Combinación de Medicamentos , Humanos , Aceites de PlantasRESUMEN
The long-term (12 months) oral administration of the aromatic retinoid Ro 10-1670 (etretin) to dogs in relatively high doses of 5.0, 15.0 and 50.0/30.0 mg/kg/day was followed by acanthotic hyperplasia of the epidermis in the external auditory meatus and dose-dependent hypertrophy and/or hyperplasia of the canine ceruminous glands. These morphological changes were accompanied by a secretory stimulation on the ceruminous glands which was slight in the low-dose dogs but in the majority of the high-dose dogs reached a degree that was followed by secondary acute infectious inflammation. The alterations in the external auditory canal ceased almost immediately when treatment of dogs with the aromatic retinoid was stopped but recommenced when it was restarted.