Asunto(s)
Dermatitis Irritante/etiología , Juglans/efectos adversos , Dermatosis de la Pierna/etiología , Extractos Vegetales/efectos adversos , Hojas de la Planta/efectos adversos , Enfermedades Cutáneas Vesiculoampollosas/etiología , Bebidas Alcohólicas , Etanol , Femenino , Humanos , Rodilla , Persona de Mediana EdadRESUMEN
BACKGROUND: Natural ingredients have variable compositions, so their allergenic potencies may differ. OBJECTIVES: To retrospectively analyse subjects reacting to herbal remedies over the past 27 years, with the aim of (i) evaluating demographic characteristics and lesion locations, (ii) describing the frequencies of positive patch test reactions, (iii) identifing sensitization sources, and (iv) studying concomitant sensitivity. PATIENTS AND METHODS: In total, 15980 patients were patch tested between 1990 and 2016 with the European baseline series and/or other series, product(s) used, and, whenever possible, the respective ingredients. RESULTS: Altogether, 8942 (56%) of 15 980 patients presented with at least one positive reaction. Reactions to topical herbal medicines, most often applied to treat an eczematous condition, leg ulcers, or other wounds, were seen in 125 (0.8%), that is, 1.4% of the contact-allergic subjects. Hands, legs and feet were the most frequently affected body sites. Twenty-one botanical allergens were identified, the commonest being Myroxylon pereirae (balsam of Peru), Compositae plants, and tincture of benzoin. Many patients presented with multiple positive test reactions, and some did not react to the commercial allergens but only to the products used. CONCLUSIONS: Topical herbal remedies should not be applied on damaged skin, as multiple sensitization may develop. Moreover, patch testing with the culprit products is important for the diagnosis.
Asunto(s)
Alérgenos/efectos adversos , Dermatitis Alérgica por Contacto/etiología , Pruebas del Parche , Preparaciones de Plantas/efectos adversos , Administración Cutánea , Adulto , Anciano , Anciano de 80 o más Años , Alérgenos/administración & dosificación , Femenino , Dermatosis del Pie/etiología , Dermatosis de la Mano/etiología , Humanos , Dermatosis de la Pierna/etiología , Masculino , Persona de Mediana Edad , Preparaciones de Plantas/administración & dosificación , Estudios Retrospectivos , Adulto JovenRESUMEN
Necrolytic acral erythema is a rare skin disease associated with hepatitis C virus infection. We report a case of a 31-year-old woman with hepatitis C virus infection and decreased zinc serum level. Physical examination revealed scaly, lichenified plaques, well-demarcated with an erythematous peripheral rim located on the lower limbs. After blood transfusion and oral zinc supplementation the patient presented an improvement of lesions.
Asunto(s)
Eritema/etiología , Hepatitis C/complicaciones , Dermatosis de la Pierna/etiología , Adulto , Eritema/tratamiento farmacológico , Eritema/patología , Femenino , Hepatitis C/tratamiento farmacológico , Hepatitis C/patología , Humanos , Dermatosis de la Pierna/tratamiento farmacológico , Dermatosis de la Pierna/patología , Erupciones Liquenoides/patología , Zinc/deficiencia , Zinc/uso terapéuticoRESUMEN
Abstract: Necrolytic acral erythema is a rare skin disease associated with hepatitis C virus infection. We report a case of a 31-year-old woman with hepatitis C virus infection and decreased zinc serum level. Physical examination revealed scaly, lichenified plaques, well-demarcated with an erythematous peripheral rim located on the lower limbs. After blood transfusion and oral zinc supplementation the patient presented an improvement of lesions.
Asunto(s)
Humanos , Femenino , Adulto , Hepatitis C/complicaciones , Eritema/etiología , Dermatosis de la Pierna/etiología , Zinc/deficiencia , Zinc/uso terapéutico , Hepatitis C/patología , Hepatitis C/tratamiento farmacológico , Erupciones Liquenoides/patología , Eritema/patología , Eritema/tratamiento farmacológico , Dermatosis de la Pierna/patología , Dermatosis de la Pierna/tratamiento farmacológicoAsunto(s)
Vesícula/etiología , Citrus aurantiifolia/efectos adversos , Dermatitis Fototóxica/etiología , Frutas/efectos adversos , Preparaciones de Plantas/efectos adversos , Luz Solar/efectos adversos , Eritema/etiología , Femenino , Humanos , Indonesia , Dermatosis de la Pierna/etiología , Adulto JovenRESUMEN
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Asunto(s)
Humanos , Femenino , Anciano , Eritema/etiología , Dermatosis de la Pierna/etiología , Calor/efectos adversos , Eritema/diagnóstico , Dermatosis de la Pierna/diagnóstico , Diagnóstico ClínicoRESUMEN
Mesotherapy is a popular procedure that poses risks that include scarring, contour changes and bacterial infections. The benefits of the procedure remain to be objectively delineated in a placebo-controlled, blinded study. Despite the lack of evidence to support its use, it is marketed as a "nonsurgical and safe" way to remove fat. The authors report a case of mycobacterial infection resulting from mesotherapy. This infection should be considered when a patient presents with a mesotherapy complication and should be discussed with the patient prior to the procedure. Options for treatment of the scarring are considered.
Asunto(s)
Cicatriz/etiología , Técnicas Cosméticas/efectos adversos , Dermatosis de la Pierna/etiología , Infecciones por Mycobacterium no Tuberculosas/etiología , Absceso/etiología , Femenino , Humanos , Inyecciones Subcutáneas/efectos adversos , Persona de Mediana EdadRESUMEN
The contact with a jellyfish is usually followed by acute inflammatory lesions, characterized by erythema, swelling, vesicles, and bullae, accompanied by burning and pain sensation. The pathogenesis is due to the direct toxic effect of the fluid contained in jellyfish tentacles. Sometimes, jellyfish may induce delayed cutaneous lesions. Delayed cutaneous reaction to jellyfish represents a clinical entity where eczematous lesions develop after days or months after contact with the invertebrate. We report the case of a patient with a delayed and persistent skin reaction due to jellyfish envenomation successfully treated with pimecrolimus.
Asunto(s)
Dermatitis Alérgica por Contacto/tratamiento farmacológico , Dermatitis Alérgica por Contacto/etiología , Hipersensibilidad Tardía/tratamiento farmacológico , Hipersensibilidad Tardía/etiología , Escifozoos , Tacrolimus/análogos & derivados , Administración Tópica , Adolescente , Animales , Mordeduras y Picaduras , Dermatitis Alérgica por Contacto/diagnóstico , Femenino , Estudios de Seguimiento , Humanos , Hipersensibilidad Tardía/diagnóstico , Dermatosis de la Pierna/diagnóstico , Dermatosis de la Pierna/etiología , Medición de Riesgo , Índice de Severidad de la Enfermedad , Pruebas Cutáneas , Tacrolimus/uso terapéutico , Factores de Tiempo , Resultado del TratamientoAsunto(s)
Suplementos Dietéticos , Queratosis/patología , Dermatosis de la Pierna/patología , Adolescente , Síndrome de Alagille/complicaciones , Síndrome de Alagille/diagnóstico , Biopsia con Aguja , Humanos , Inmunohistoquímica , Queratosis/tratamiento farmacológico , Queratosis/etiología , Dermatosis de la Pierna/tratamiento farmacológico , Dermatosis de la Pierna/etiología , Masculino , Pronóstico , Medición de Riesgo , Índice de Severidad de la Enfermedad , Extremidad Superior/patología , Deficiencia de Vitamina A/complicaciones , Deficiencia de Vitamina A/diagnósticoRESUMEN
This report discusses a case of a 69-year-old woman who developed chronic non-healing leg ulcers after long-term topical use of Plectranthus amboinicus. The ulcer was proven to be allergic contact dermatitis to P. amboinicus by a patch test. The ulcer healed after discontinuation of P. amboinicus. To the best of our knowledge, this is the first reported case of allergic contact dermatitis to P. amboinicus masquerading as chronic leg ulcer.
Asunto(s)
Dermatitis Alérgica por Contacto/diagnóstico , Dermatosis de la Pierna/diagnóstico , Fitoterapia/efectos adversos , Plectranthus/efectos adversos , Administración Tópica , Anciano , Dermatitis Alérgica por Contacto/etiología , Diagnóstico Diferencial , Femenino , Humanos , Dermatosis de la Pierna/etiología , Úlcera de la Pierna/diagnósticoRESUMEN
A 70-year-old woman presented for evaluation of symmetric necrotic ulcers of the lower extremities. Biopsy results revealed changes consistent with calciphylaxis. The predisposing factors in this patient included calcium supplementation, obesity, female gender, viscous blood, renal failure, and diabetes mellitus. To our knowledge, this is the first report of calciphylaxis occurring in the setting of chronic myelomonocytic leukemia. We discuss the history, clinical presentation, diagnosis, and treatment of calciphylaxis.
Asunto(s)
Calcifilaxia/diagnóstico , Dermatosis de la Pierna/diagnóstico , Leucemia Mielomonocítica Crónica/diagnóstico , Anciano , Biopsia , Calcifilaxia/etiología , Diagnóstico Diferencial , Femenino , Humanos , Dermatosis de la Pierna/etiología , Leucemia Mielomonocítica Crónica/complicaciones , Factores de RiesgoRESUMEN
Telangiectasia macularis eruptiva perstans (TMEP) is a cutaneous form of mastocytosis. It has been rarely associated with an underlying myeloproliferative disorder. We report the case of a patient, while receiving treatment for thrombocytosis, with both platelet production and function inhibitors presented with TMEP. TMEP is often refractory to therapy; however, our patient responded to treatment with PUVA.
Asunto(s)
Dermatosis de la Pierna/etiología , Mastocitosis Cutánea/etiología , Enfermedades Cutáneas Vasculares/etiología , Telangiectasia/etiología , Trombocitosis/complicaciones , Femenino , Humanos , Dermatosis de la Pierna/tratamiento farmacológico , Mastocitosis Cutánea/tratamiento farmacológico , Persona de Mediana Edad , Terapia PUVA , Policitemia Vera/complicaciones , Enfermedades Cutáneas Vasculares/tratamiento farmacológico , Telangiectasia/tratamiento farmacológicoAsunto(s)
Enfermedades Renales/complicaciones , Dermatosis de la Pierna/etiología , Dermatosis de la Pierna/terapia , Terapia Ultravioleta , Colágeno Tipo I/genética , Colágeno Tipo III/genética , Factor de Crecimiento del Tejido Conjuntivo , Femenino , Fibrosis , Humanos , Proteínas Inmediatas-Precoces/genética , Péptidos y Proteínas de Señalización Intercelular/genética , Dermatosis de la Pierna/metabolismo , Dermatosis de la Pierna/patología , Persona de Mediana Edad , ARN Mensajero/metabolismo , Factor de Crecimiento Transformador beta/genética , Factor de Crecimiento Transformador beta1RESUMEN
Disseminated superficial actinic porokeratosis (DSAP) is associated with sun exposure and tanning bed usage and has been rarely reported in association with systemic PUVA. We report the first case of DSAP occurring after topical foot PUVA.
Asunto(s)
Dermatosis del Pie/etiología , Dermatosis de la Pierna/etiología , Terapia PUVA/efectos adversos , Poroqueratosis/etiología , Femenino , Humanos , Persona de Mediana EdadRESUMEN
INTRODUCTION: The risk of vitamin C deficiency is underestimated in industrialized countries and is only disclosed in rare cases of severe scurvy. CASE REPORT: We report three cases of scurvy presenting with ecchymotic purpura and hemorrhagic ulcerations of the lower limbs. Vitamin C supplementation led to rapid improvement of the skin lesions. DISCUSSION: Clinical diagnosis of low-grade deficiency can be difficult. Biological diagnosis requires special care in sample taking and transport.
Asunto(s)
Equimosis/etiología , Hemorragia/etiología , Dermatosis de la Pierna/etiología , Úlcera de la Pierna/etiología , Púrpura/etiología , Escorbuto/complicaciones , Anciano , Anciano de 80 o más Años , Ácido Ascórbico/sangre , Ácido Ascórbico/uso terapéutico , Deficiencia de Ácido Ascórbico/sangre , Deficiencia de Ácido Ascórbico/complicaciones , Deficiencia de Ácido Ascórbico/tratamiento farmacológico , Diagnóstico Diferencial , Femenino , Humanos , Factores de Riesgo , Escorbuto/sangre , Escorbuto/tratamiento farmacológicoRESUMEN
BACKGROUND: Solar urticaria is a rare photosensitive disease, and its differential diagnosis with respect to polymorphous light eruption is sometimes difficult. We report our experience with 25 cases of solar urticaria and discuss the pitfalls in phototesting such patients. OBSERVATION: The most important locations in this patient series are the V of the neck and the arms, which are similar to those of polymorphous light eruption. In all of the patients, however, the lesions appeared within 30 minutes of sun exposure or phototesting and disappeared within 24 hours. Notably, 12 (48%) of the patients had a history of atopy. Phototesting helps confirm the diagnosis, but, in some patients, this was difficult. CONCLUSIONS: A negative phototest result from a single light source does not necessarily exclude a diagnosis of solar urticaria. In patients in whom phototesting elicits negative reactions, other light sources should be used, and, if the phototest result is still negative, a provocative test with natural sunlight should be done. Histamine1-receptor antihistamines are a useful first-line therapy, although more severely affected persons may require prophylactic courses of phototherapy or photochemotherapy. The main problem is maintenance treatment.
Asunto(s)
Trastornos por Fotosensibilidad/etiología , Pruebas Cutáneas/métodos , Luz Solar/efectos adversos , Urticaria/etiología , Adolescente , Adulto , Anciano , Brazo/patología , Dermatitis Atópica/complicaciones , Diagnóstico Diferencial , Dermatosis Facial/diagnóstico , Dermatosis Facial/etiología , Dermatosis del Pie/diagnóstico , Dermatosis del Pie/etiología , Dermatosis de la Mano/diagnóstico , Dermatosis de la Mano/etiología , Antagonistas de los Receptores Histamínicos H1/uso terapéutico , Humanos , Dermatosis de la Pierna/diagnóstico , Dermatosis de la Pierna/etiología , Luz , Persona de Mediana Edad , Cuello/patología , Fotoquimioterapia , Trastornos por Fotosensibilidad/diagnóstico , Trastornos por Fotosensibilidad/tratamiento farmacológico , Trastornos por Fotosensibilidad/prevención & control , Fototerapia , Hombro/patología , Pruebas Cutáneas/instrumentación , Factores de Tiempo , Urticaria/diagnóstico , Urticaria/tratamiento farmacológico , Urticaria/prevención & controlRESUMEN
Adverse cutaneous reactions to topically applied olive oil are seldom reported, and positive patch tests to it are mostly regarded as allergic. To evaluate such "positive" patch test reactions, 77 female (mean age: 44 years) and 23 male eczema patients (mean age: 46 years) were prospectively patch tested with freshly prepared olive oil. Tests were performed openly (including ROAT) as well as using Al-tests and Finn Chambers on Scanpor. 5 patients (2 male) showed "positive" test reactions (all patients at the Al-test site, 3 at the Finn Chamber site, 1 with ROAT). In only 1 patient could the reaction be classified as probably allergic, in contrast to previous reports. In conclusion, olive oil is very weakly irritant in general, but bears relevant irritant capacity when applied under occlusive conditions. Therefore, olive oil appears to be less than suitable for the topical therapy of patients with venous insufficiency and associated eczema of the lower extremities.
Asunto(s)
Dermatitis Alérgica por Contacto/etiología , Dermatitis Irritante/etiología , Fármacos Dermatológicos/efectos adversos , Aceites de Plantas/efectos adversos , Adulto , Anciano , Anciano de 80 o más Años , Alérgenos/efectos adversos , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Irritante/diagnóstico , Dermatitis Profesional/etiología , Cámaras de Difusión de Cultivos , Eccema/etiología , Femenino , Dermatosis de la Mano/etiología , Humanos , Irritantes/efectos adversos , Dermatosis de la Pierna/etiología , Masculino , Persona de Mediana Edad , Apósitos Oclusivos , Aceite de Oliva , Pruebas del Parche , Estudios Prospectivos , Cuidados de la Piel , Insuficiencia Venosa/fisiopatologíaRESUMEN
Jellyfish envenomation can cause an immediate local skin reaction, which is usually a painful linear vesiculourticarial eruption. Persistent, delayed, or recurrent dermatitis is less common. Because jellyfish sting reactions and their management are unfamiliar to family physicians, we describe a case of recurrent local dermatitis after jellyfish envenomation and suggest appropriate treatment.