RESUMEN
Mesotherapy is widely used for its lipolytic effect as an alternative procedure to surgical methods. Although many benefits of lipolytic mesotherapy have been observed, numerous side effects have also been reported. Here, we report a case of cutaneous foreign body granulomas that occurred after lipolytic mesotherapy.
Asunto(s)
Granuloma de Cuerpo Extraño/inducido químicamente , Dermatosis de la Pierna/inducido químicamente , Mesoterapia/efectos adversos , Adulto , Celulitis/tratamiento farmacológico , Quimioterapia Combinada/efectos adversos , Femenino , HumanosAsunto(s)
Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Alérgica por Contacto/etiología , Emolientes/efectos adversos , Helichrysum/efectos adversos , Fitoterapia/efectos adversos , Preparaciones de Plantas/efectos adversos , Administración Cutánea , Anciano , Emolientes/administración & dosificación , Femenino , Dermatosis de la Mano/inducido químicamente , Humanos , Dermatosis de la Pierna/inducido químicamente , Pruebas del ParcheRESUMEN
A 64-year-old woman presented with a hemorrhagic perifollicular rash on her legs while taking warfarin. After biopsy, vitamin C deficiency was suggested as the diagnosis, which ascorbic acid assays later confirmed. Clinical resolution of the rash followed supplementation with vitamin C. Patients on a vitamin K limited diet may also be limiting their intake of vitamin C. Physicians should be aware of this possible correlation, and consider checking vitamin C levels in patients with a perifollicular hemorrhagic rash or other signs of vitamin C deficiency while on warfarin.
Asunto(s)
Anticoagulantes/efectos adversos , Deficiencia de Ácido Ascórbico/inducido químicamente , Warfarina/efectos adversos , Ácido Ascórbico/uso terapéutico , Deficiencia de Ácido Ascórbico/diagnóstico , Deficiencia de Ácido Ascórbico/tratamiento farmacológico , Erupciones por Medicamentos/diagnóstico , Erupciones por Medicamentos/etiología , Femenino , Humanos , Dermatosis de la Pierna/inducido químicamente , Dermatosis de la Pierna/diagnóstico , Persona de Mediana Edad , Enfermedades Cutáneas Vasculares/inducido químicamente , Enfermedades Cutáneas Vasculares/diagnósticoAsunto(s)
Dermatitis Alérgica por Contacto/etiología , Emolientes/efectos adversos , Formaldehído/efectos adversos , Lonicera/efectos adversos , Extractos Vegetales/efectos adversos , Adulto , Emolientes/química , Femenino , Formaldehído/análisis , Humanos , Dermatosis de la Pierna/inducido químicamente , Lonicera/química , Pruebas del Parche , Extractos Vegetales/química , Embalaje de ProductosAsunto(s)
Anticonvulsivantes/toxicidad , Neuritis del Plexo Braquial/tratamiento farmacológico , Erupciones por Medicamentos/diagnóstico , Dermatosis del Pie/inducido químicamente , Fructosa/análogos & derivados , Granuloma Anular/inducido químicamente , Dermatosis de la Pierna/inducido químicamente , Trastornos Migrañosos/tratamiento farmacológico , Adulto , Anticonvulsivantes/uso terapéutico , Biopsia , Erupciones por Medicamentos/patología , Femenino , Dermatosis del Pie/diagnóstico , Dermatosis del Pie/tratamiento farmacológico , Dermatosis del Pie/patología , Fructosa/uso terapéutico , Fructosa/toxicidad , Granuloma Anular/diagnóstico , Granuloma Anular/tratamiento farmacológico , Granuloma Anular/patología , Humanos , Dermatosis de la Pierna/diagnóstico , Dermatosis de la Pierna/tratamiento farmacológico , Dermatosis de la Pierna/patología , Terapia PUVA , Recurrencia , Piel/patología , TopiramatoAsunto(s)
Dermatitis Alérgica por Contacto/etiología , Dermatitis Irritante/etiología , Dermatosis de la Pierna/inducido químicamente , Hojas de la Planta/efectos adversos , Plantago/efectos adversos , Adulto , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Irritante/diagnóstico , Femenino , Humanos , Masculino , Persona de Mediana Edad , Fitoterapia/efectos adversosRESUMEN
The association of vitamin C deficiency with nutritional factors is commonly recognized. However, an acute form of scurvy can occur in patients with an acute systemic inflammatory response, which is produced by sepsis, medications, cancer or acute inflammation. The frequency of acute hypovitaminosis C in hospitalized patients is higher than previously recognized. We report the occurrence of acute signs and symptoms of scurvy (perifollicular petechiae, erythema, gingivitis and bleeding) in a patient hospitalized for treatment of metastatic renal-cell carcinoma with high-dose interleukin-2. Concomitantly, serum vitamin C levels decreased to below normal. Better diets and longer lifespan may result a lower frequency of acute scurvy and a higher frequency of scurvy associated with systemic inflammatory responses. Therefore, increased awareness of this condition can lead to early recognition of the cutaneous signs of acute scurvy in hospitalized patients with acute illnesses or in receipt of biological agents, and prevent subsequent morbidity such as bleeding, anaemia, impaired immune defences, oedema or neurological symptoms.