RESUMEN
Ocular contents from a horse with a 4-week history of severe unilateral uveitis were submitted for histopathologic examination. A severe unilateral granulomatous chorioretinitis with intralesional Halicephalobus deletrix was diagnosed. The horse developed progressive neurologic signs several days following the surgery to remove ocular contents and implant a prosthesis and was subsequently euthanatized. A severe multifocal granulomatous encephalitis with intralesional H. deletrix, localized primarily to the optic chiasm, thalamus, and brain stem, was diagnosed from tissues acquired at necropsy. The other eye was not affected. This is the first report of ocular parasitism by H. deletrix and suggests possible systemic dissemination from a primary site in the eye.
Asunto(s)
Coriorretinitis/veterinaria , Infecciones Parasitarias del Ojo/veterinaria , Enfermedades de los Caballos/patología , Infecciones por Rhabditida/veterinaria , Uveítis/veterinaria , Animales , Tronco Encefálico/patología , Coriorretinitis/parasitología , Coriorretinitis/patología , Encefalomielitis Equina/patología , Infecciones Parasitarias del Ojo/patología , Enfermedades de los Caballos/parasitología , Caballos , Masculino , Infecciones por Rhabditida/patología , Tálamo/patología , Uveítis/parasitología , Uveítis/patologíaRESUMEN
Two spontaneous neurodegenerative diseases of the horse, equine motor neuron disease (EMND) and equine degenerative myeloencephalopathy (EDM), have been associated with alpha-tocopherol deficiency, and both were characterized by prominent accumulations of endothelial lipopigment in the small vessels of the spinal cord. These endothelial pigment deposits appear to be reversible. In EMND horses pasture-supplemented for 9 months or more after the progression of weakness and wasting had arrested, there was very little endothelial lipopigment. The origin and the potential effects of these endothelial lipopigment accumulations are discussed.