Asunto(s)
Conducta Cooperativa , Comunicación Interdisciplinaria , Neoplasias de Oído, Nariz y Garganta/patología , Derivación y Consulta , Actitud del Personal de Salud , Carcinoma de Células Escamosas/patología , Current Procedural Terminology , Errores Diagnósticos , Eficiencia Organizacional , Alemania , Ganglios Linfáticos/patología , Programas Nacionales de Salud , Invasividad Neoplásica , Enfermedades Otorrinolaringológicas/patología , Garantía de la Calidad de Atención de Salud , Terminología como Asunto , Carga de TrabajoRESUMEN
Epidermolysis bullosa acquisita (EBA) is a rare, chronic, acquired bullous autoimmune dermatosis. It is characterized by the formation of IgG autoantibodies against type VII procollagen of anchoring fibrils with subepidermal formation of bullous lesions and consequent scarring. The epidemiology of this disease and its characteristic clinical findings cannot be completely surveyed at present due to the limited number of available publications. In general, bullous lesions form on the entire integument and can also involve mucosa. The development of scar-related adhesions on the mucosa of the upper airways and esophagus can lead to serious complications that are difficult to treat. We report our experience in managing a 44-year-old male patient in whom the diagnosis of EBA was established in 1993 on the basis of multiple persistent bullous lesions involving the eye, nose, skin and oral, pharyngeal and laryngeal mucosa. After failing previous medical and surgical therapies, interdisciplinary management resulted in the control of active lesions with extracorporal phototherapy and cyclosporin A.
Asunto(s)
Epidermólisis Ampollosa Adquirida/diagnóstico , Enfermedades Otorrinolaringológicas/diagnóstico , Adulto , Autoanticuerpos/sangre , Terapia Combinada , Ciclosporina/administración & dosificación , Epidermólisis Ampollosa Adquirida/inmunología , Epidermólisis Ampollosa Adquirida/patología , Humanos , Inmunoglobulina G/sangre , Masculino , Membrana Mucosa/inmunología , Membrana Mucosa/patología , Enfermedades Otorrinolaringológicas/inmunología , Enfermedades Otorrinolaringológicas/patología , Grupo de Atención al Paciente , Fototerapia , Procolágeno/inmunologíaRESUMEN
The alien structure, being not the own cells of patient observed in cytologic specimens in otolaryngologic practice were described. The pollen, Actinomyces and mycotic cells as well as the inorganic particles were found.