An ethnobotanical study of plants used for the treatment of sexually transmitted diseases (njovhera) in Guruve District, Zimbabwe.

The use of medicinal plants in Guruve District, Zimbabwe, contributes significantly to primary health care of the people of the area. This paper presents findings of a survey of plants used for the treatment of sexually transmitted diseases (STDs) in the district. Ethnobotanical information obtained from traditional herbalists and other knowledgeable rural dwellers, has revealed 15 plant species belonging to 10 families as medicinal plants used for the treatment of these infections in the area. Six of these are the commonest and most frequently prescribed by the healers. Roots are the most frequently used parts of the plants constituting 53% of preparations while oral administration of extracts is the main method of prescription. Based on the information gathered from the traditional healers, Acacia nilotica (L.) Willd. ex Delile, Cassia abbreviata Oliv. Dichrostachys cinerea Wight and Arn, Solanum incanum L., Vernonia amygdalina Del. and Zanha africana (Radlk) Excell. are the most frequently used plants for the treatment of STDs. The methanol extracts of Cassia abbreviata, Zanha africana and Acacia nilotica showed significant inhibition against Gram-positive and Gram-negative bacteria, while acetone extracts of these plants inhibited most of the species. Generally the water extracts show less activity than acetone and methanol extracts.

Studies on pharmaceutical ethnobotany in the region of Pallars (Pyrenees, Catalonia, Iberian Peninsula). Part I. General results and new or very rare medicinal plants.

An ethnobotanical survey was carried out in the region called Pallars--constituted by two districts, Pallars Sobirà and Pallars Jussà--situated in the Central Pyrenees, in North West Catalonia (Iberian Peninsula), with an approximate area of 2530 km(2) and a population of 19000. We obtained data on 437 plant species used for health care through interviews with 264 people. We detected 867 unreported or uncommon uses corresponding to 272 plant species, 52 of which had never or very rarely been cited as medicinal. To present the most important findings concerning the ethnopharmacology of the area studied, this first part includes the general results and the new or very scarcely reported medicinal vascular plants. Further papers will deal with unreported or very uncommon uses for known medicinal plant species and with medicinal non-vascular plants.

Caries inhibitory activity of cacao bean husk extract in in-vitro and animal experiments.

Cacao bean husk extract (CBH) was examined for inhibitory effects on the caries-inducing properties of mutans streptococci in vitro and on caries development in specific pathogen-free Sprague-Dawley rats infected with mutans streptococci. CBH reduced the growth rate of almost all oral streptococci examined, which resulted in the reduction of acid production. Furthermore, insoluble glucan synthesis by the glucosyltransferases from Streptococcus mutans MT8148R and Streptococcus sobrinus 6715 was significantly inhibited by CBH. Hence, the sucrose-dependent cell adherence of mutans streptococci was also depressed by CBH. The administration of CBH in drinking water resulted in significant reductions of caries development and dental plaque accumulation in rats infected with either Strep. sobrinus 6715 or Strep. mutans MT8148R, and the minimum cariostatic concentration was 1.0 mg/ml. These results indicate that CBH possesses powerful anticariogenic potential.

[The effect of an extract of aspen bark on the development of a chronic ulcerative process in animal stomachs]. / Izuchenie vliianiia ékstrakta kory osiny na razvitie khronicheskogo iazvennogo protsessa v zheludke u zhivotnykh.

The antiulcerogenic activity of aspen bark extract was demonstrated in experiments on a model of gastric ulcer in rats. Treatment with a 100 mg/kg dose of aspen bark extract led to decrease in the size and more active healing of the ulcerous defect in all follow-up periods.