[The information-wave hypothesis of a pain]. / Iformatsiino-khvyl'ova hipoteza boliu.

Proofs of existence in organism of two systems of nociceptive stimuli reception are submitted. The first system belongs to the neuro-endocrine system which forms painful reactions, the second one is connected with "alive matrix"--uniform system of the connective tissue which connects an environment through acupuncture points with intercellular space, and also with intracellular structures of each cell. "Alive matrix" carries out the information management of physiological processes and participates in electromagnetoreception, supervising electromagnetic parameters of an organism--"electromagnetic homeostasis". Acupuncture points carry out the role of electromagnetoreceptors. The layers of interstitial connective tissue, meridians, perform the balancing of a uniform physical field of an organism and transfer the information about its disturbances. The system of electromagnetoreception supervises the shifts in electromagnetic homeostasis of the organism. Damaging factors, physical and chemical changes in the pathological loci and fluctuations of a geomagnetic fields change a uniform physical field of an organism and initiate the compensatory responses of neuro-endocrine system. The information-wave hypothesis of a pain adequately explains effective treatment of illnesses by low intensive electromagnetic fields. The recognition of electromagnetic sensory system allows to explain the mechanism of their high medical efficiency in therapy of a pain and opens a way of new strategy, where instead of pharmacology (with its side action) safe technologies of information-wave therapy are used.

The effects of proton exposure on neurochemistry and behavior.

Future space missions will involve long-term travel beyond the magnetic field of the Earth, where astronauts will be exposed to radiation hazards such as those that arise from galactic cosmic rays. Galactic cosmic rays are composed of protons, alpha particles, and particles of high energy and charge (HZE particles). Research by our group has shown that exposure to HZE particles, primarily 600 MeV/n and 1 GeV/n 56Fe, can produce significant alterations in brain neurochemistry and behavior. However, given that protons can make up a significant portion of the radiation spectrum, it is important to study their effects on neural functioning and on related performance. Therefore, these studies examined the effects of exposure to proton irradiation on neurochemical and behavioral endpoints, including dopaminergic functioning, amphetamine-induced conditioned taste aversion learning, and spatial learning and memory as measured by the Morris water maze. Male Sprague-Dawley rats received a dose of 0, 1.5, 3.0 or 4.0 Gy of 250 MeV protons at Loma Linda University and were tested in the different behavioral tests at various times following exposure. Results showed that there was no effect of proton irradiation at any dose on any of the endpoints measured. Therefore, there is a contrast between the insignificant effects of high dose proton exposure and the dramatic effectiveness of low dose (<0.1 Gy) exposures to 56Fe particles on both neurochemical and behavioral endpoints.