Resolution of Recurrent Oro-facial Herpes Simplex Using a Topical Botanical Gel: A Case Report.

Oral herpes labialis, more commonly known as cold sores, are a common encountered viral infection involving herpes simplex virus-1 (HSV-1). Although relatively benign, these lesions can be both unsightly and clinically difficult to manage. Prescription standards of care and over-the-counter agents, such as docosonal, have often shown only limited efficacy in both decreasing lesional pain and reducing duration of lesional symptomology and are not without potential side effects. Despite some success with acute remediation, recurrent episodes often occur, with seemingly no imparted protection or suppression against future outbreaks. This case report involves the successful treatment of oro-facial herpes labialis with a synergistic botanical blend with marked reduction in symptoms, pain score, and lesion duration. Monitoring and evaluation post-treatment and application during future prodromal symptoms was also performed demonstrating additional reduction in the frequency of subsequent outbreaks. This case report supports the use of this treatment for prodromal and acute treatment of oro-facial herpes infection and appears to impart a reduction in the frequency of future outbreaks.

Photo Rounds: Painful facial blisters, fever, and conjunctivitis.

Following Tx for facial blisters, our patient returned with what appeared to be viral conjunctivitis. Further evaluation revealed a missed tip-off to the proper Dx.

A clinical pilot study of lignin--ascorbic acid combination treatment of herpes simplex virus.

Antiviral drugs as well as natural remedies have been used to reduce symptoms and the rate of recurrences of herpes simplex virus type 1 (HSV-1) infection, a common disease. To evaluate anti-HSV-1 activity of a pine cone lignin and ascorbic acid treatment, a clinical pilot study was carried out. Forty-eight healthy patients of both genders between 4 and 61 years old (mean: 31+/-16 years), with active lesions of HSV-1, took part in the study. According to the HSV-1 stage at the presentation, the patients were classified into the prodromic (16 patients), erythema (11 patients), papule edema (1 patient), vesicle/pustule (13 patients) and ulcer stages (7 patients). One mg of lignin-ascorbic acid tablet or solution was orally administered three times daily for a month. Clinical evaluations were made daily the first week and at least three times a week during the second week after the onset and every six months during the subsequent year to identify recurrence episodes. The patients who began the lignin-ascorbic acid treatment within the first 48 hours of symptom onset did not develop HSV-1 characteristic lesions, whereas those patients who began the treatment later experienced a shorter duration of cold sore lesions and a decrease in the symptoms compared with previous episodes. The majority of the patients reported the reduction in the severity of symptoms and the reduction in the recurrence episodes after the lignin-ascorbic acid treatment compared with previous episodes, suggesting its possible applicability for the prevention and treatment of HSV-1 infection.

A utilização do laser no tratamento do herpes labial / The use of laser in the treatment of herpes labialis

O herpes é uma doença infecto-contagiosa comum, causada pelo herpes vírus humano. Os sintomas apresentados em geral são: prurido, ardência ou dor no local em que aparecem as múltiplas vesículas. Muitos tratamentos têm sido propostos para o tratamento do herpes labial, porém nenhum deles conseguiu evitar o reaparecimento das lesões. A utilização do laser é proposta como coadjuvante no tratamento do herpes labial, com a vantagem de diminuir o tempo de latência e a freqüência de aparecimento das lesões. O objetivo deste estudo foi avaliar os protocolos utilizados no LELO no período de janeiro de 2004 a maio de 2006 e compará-los com os métodos propostos atualmente na literatura. Resultados: Os protocolos para o tratamento do herpes na fase de vesícula variaram de 0,7 a 1,5 W (laser de alta potência). Na fase de crosta, o laser de baixa potência, no modo vermelho, foi utilizado com parâmetros entre 3 e 5 J/cm². Em prevenção, laser de baixa potência, infravermelho, de 4 a 5 J/cm². Concluiu-se que os parâmetros ideais para o tratamento do herpes variam de acordo com o estágio da lesão, sendo na fase de vesícula o protocolo de 1 W com o laser de alta potência; na fase de crosta 4 J/cm² modo vermelho; e para prevenção, 5 J/cm² no infravermelho. Esses protocolos podem variar de acordo com as necessidades específicas de cada paciente.

Thiersch grafting in recurrent herpes-induced lip depigmentation.

Recurrent herpes induced lip-depigmentation is an uncommon condition observed rarely in patients suffering from recurrent herpes labialis. Patients usually belong the age group between 20 and 40 who have had herpes labialis for 4--12 years. These patients do not respond to available methods of treatment such as psoralens and phototherapy because there is reactivation of the virus. Ten cases of recurrent herpes-induced lip depigmentation (HILD) were successfully treated with a combination therapy of acyclovir 400 mg twice a day for one year with Thiersch grafting six months after starting therapy.

Acupuncture treatment for herpes simplex infections. A clinical case report.

Herpes simplex is a common skin disorder. There is no effective cure. The recent introduction of drugs, such as acyclovir, is indeed a great advance in its therapeutics. However, these drugs may only modestly reduce the length of an attack, but do not lengthen the remission nor prevent recurrences. Our very limited experience in two cases of herpes oral-labialis and three cases of herpes genitalis with acupuncture treatment seemed to indicate the possibility of a marked reduction of an episode, a lengthening of the remission, and a prevention of recurrences. We hope our report would encourage our colleagues to try acupuncture in the clinical management of herpes cases and to study its immunologic effects.

Herpes simples recorrente labial: avaliação clínica da terapêutica com anestésico local / Recurrent labial herpes simplex: clinical evaluation of the therapeutics with local anesthetics

Oa autores fazem um estudo em humanos, utilizando o anestésico local como terapêutica do Herpes Simples recidivante dos lábios, infiltrando intralesionalmente esta solução