[Correlation Study on Syndrome Types of Chinese Medicine in Dysfunctional Uterine Bleeding Patients and Serum Sex Hormones].

Objective To observe the correlation between serum sex hormone levels and different syndrome types of Chinese medicine (CM) in dysfunctional uterine bleeding (DUB) patients. Methods Totally 532 DUB patients were classified into 10 different syndrome types according to syndrome typing theories of CM, including Gan-depression transforming heat syndrome, Shen deficiency blood sta- sis syndrome, Shen-yin deficiency syndrome, Pi-Shen deficiency syndrome, qi and yin deficiency syndrome, qi and blood deficiency syndrome, Pi deficiency syndrome, qi stagnation blood stasis syndrome, damp-heat syndrome, yin deficiency blood heat syndrome. Besides, 6 serum levels of sex hormone were measured including follicular stimulating hormone (FSH) , luteinizing hormone (LH) , estradiol (E2) , progesterone (P) , testerone (T) , and prolactin (PRL) in patients with different syndrome types. Correlation study between syndrome types and sex hormones were performed using Logistic regression analysis. Results The distributions of DUB in CM were sequenced from high to low as uterine bleeding, menostaxis, preceded menstrual cycle, intermenstrual bleeding, and menorrhagia. The distributions of syndrome types were sequenced from high to low as yin deficiency blood heat syndrome, qi and blood deficiency syndrome, qi stagnation blood stasis syndrome, Shen-yin deficiency syndrome, Pi-Shen deficiency syndrome, Gan-depression transforming heat syndrome, Pi deficiency syndrome, Shen deficiency blood stasis syndrome, qi and yin deficiency syndrome, damp-heat syndrome. PRL level was positively correlated with Gan-depression transforming heat syndrome in the ratio of 1. 117 (P <0. 05). FSH level was positively correlated with Shen-yin deficiency syndrome in the ratio of 1. 327 (P <0. 05). LH level was positively correlated with Pi-Shen deficiency syndrome in the ratio of 1.342 (P <0.05). Conclusions DUB patients with various syndrome types of CM had different levels of sex hormones, with certain-laws manifested. Positive correlation existed between PRL level and Gan-depression transforming heat syn- drome, FSH level and Shen-yin deficiency syndrome, LH level and Pi-Shen deficiency syndrome.

[Good practice and accuracy of office hysteroscopy and endometrial biopsy]. / Bonne pratique et valeur diagnostique de l'hystéroscopie diagnostique et des prélèvement histologiques.

Office hysteroscopy may be performed without anaesthesia. Endometrial biopsy can be performed during hysteroscopy. Antalgics or other treatment to reduce discomfort are not indicated. Prophylactic antibiotics are not indicated. Diagnostic value of hysteroscopy for endometrial pathology is interesting. Pipelle is the most appropriate instrument for endometrial biopsy.

Hallazgos histeroscópicos en la hemorragia uterina anormal con biopsia a ciegas previa negativa / Hysteroscopic findings in abnormal uterine bleeding with a previous negative blind biopsy

Estudiamos una muestra de 408 pacientes, en un estudio retrospectivo, tratando de evaluar la fiabilidad del estudio biópsico a ciegas para el diagnóstico de la patología endometrial. Se realiza histeroscopia diagnóstica en aquellas pacientes que presentan algún tipo de hemorragia uterina anormal (HUA). Premenopáusicas (267); posmenopáusicas (141); cíclicas (305); acíclicas (103), y que previamente han sido estudiadas con una biopsia endometrial con resultado negativo (legrado en posmenopáusicas y en hemorragias cíclicas y biopsia endometrial [Z-sampler] en premenopáusicas). Realizamos estudio estadístico con pruebas de la X2 mediante análisis informático SPSS. La biopsia endometrial presenta un alto índice de falsos negativos; no diagnosticando, en este estudio, hasta un 37,2 por ciento de patología orgánica en premenopáusicas y un 43,8 por ciento en posmenopáusicas, fundamentalmente a expensas de pólipos y miomas e incluso adenocarcinomas de endometrio (1,4 por ciento). Los hallazgos histeroscópicos no fueron condicionados por el tipo de hemorragia ni por la condición premenopáusica o posmenopáusica. La histeroscopia debe ser considerada el método diagnóstico de elección en el estudio de la hemorragia uterina anormal, y debe combinarse siempre con el diagnóstico anatomopatológico (AU)