Challenging Case of Parotitis: A Comprehensive Approach.

The diagnosis and management of parotitis can be challenging. Patients often present with pain and edema in the neck, jaw, head, and ear due to congestion of the gland. Parotitis is typically caused by an infection within the parotid gland and surrounding lymph nodes, and the infection can spread to nearby cervical fascial planes and cause major complications if not managed successfully. Specific guidelines for the outpatient management of parotitis are limited, and outpatient treatment failures are common, requiring inpatient therapy with multiple broad-spectrum antibiotics. In the current case, a comprehensive patient-centered approach was used to treat a woman whose overlapping clinical conditions, lifestyle, and work factors led to an infection of the parotid gland.

Effects of huangqi and bear bile on recurrent parotitis in children: a new clinical approach.

OBJECTIVE: To evaluate the pharmacological effects of traditional Chinese medicine, bear bile capsule and Huangqi granule, on recurrent parotitis in children. METHODS: In this prospective, controlled, and randomized study, a total of 151 young children were divided into three groups: Group A included massaging the children's parotid region and melting vitamin C in their mouth daily; Group B included swallowing bear bile capsule and Huangqi granule daily; and Group C included massages and vitamin C as prescribed in Group A, and traditional Chinese medicine as prescribed in Group B. Children were treated individually for one month and then a follow-up study was conducted for 1 to 3.5 years. Analysis of variance (ANOVA) and Ridit analysis were employed for statistical analysis. RESULTS: The recurrence rate decreased in every group, but was significantly more in Groups B and C when compared to Group A. The recurrences significantly decreased (P<0.01) in Group B and their recovery rate was as high as 63%, significantly better than those of the other groups (P<0.01). CONCLUSIONS: Huangqi and bear bile could be a novel clinical approach for treating recurrent parotitis in children.

Aplicación del propóleos en el tratamiento de la parotiditis crónica del niño / Use of propolis in pediatric chronic parotitis treatment

Objetivo: Analizar los resultados obtenidos al aplicar el propóleos como tratamiento de la parotiditis bacteriana crónica recurrente. Se aplicó propóleos como agente terapéutico y profilàctico de la parotiditis crónica recurrente, en 12 pacientes pediàtricos, a razón de 10 gotas del propóleos hidroalcohólico al 10 por ciento, con el que realizó una buchada de 2 minutos y después lo deglutió, una vez al día, durante un mes y se repitió el ciclo a los 2 meses. Se realizó seguimiento por 6 meses. La muestra estuvo dividida en 2 grupos de edades: de 18 meses a 5 años (58,3 por ciento) y mayores de 5 y hasta 12 años (41,7 por ciento). Los varones constituyeron el 41,7 por ciento de la muestra. La gravedad de la enfermedad: grave (33,3 por ciento), moderada (58,3 por ciento) y leve (8,4 por ciento). El 75 por ciento de los pacientes fueron curados y mejorados el 25 por ciento. El uso del propóleos fue eficaz en el tratamiento de la parotiditis crónica recurrente del niño, disminuyendo el uso de antibióticos convencionales(AU)

Objective: To analyze the results obtained applying the propolis in treatment of recurrent chronic bacterial parotitis. Propolis was administered as a therapeutical and prophylactic agent in 12 pediatric patients (10 drops of 10 percent hydroalcoholic propolis) with a 2 min mouthful and then swallowed, daily over a month and cycle was repeated at two months. We made a 6 month follow up. Sample was divided into 2 age groups: from 18 months to 5 years (58.3 percent) and over 5 and up to 12 years (41.7 percent). Male sex accounted for the 41.7 percent of sample. Disease severity: Severe (33.3 percent), moderate (58.3 percent) and light (8.4 percent). The 75 percent of patients were cured and the 25 percent improved, since they had some signs without need of antibiotic-therapy. The propolis use was efficacious in pediatric recurrent chronic parotitis treatment, decreasing the conventional antibiotic use(AU)

Mycobacterium fortuitum-induced persistent parotitis: successful therapy with clarithromycin and ciprofloxacin.

BACKGROUND: Parotitis caused by nontuberculous mycobacteria, a very rare disease entity, has never been reported to be caused by Mycobacterium fortuitum (M. fortuitum) in the literature. METHODS AND RESULTS: An 8-year-old girl was seen with painful swelling of the right parotid gland despite antibiotic treatment of more than 1 month. Elevated serum amylase activity and diffuse contrast-enhanced CT of the parotid gland confirmed the diagnosis of parotitis. Histopathological study of specimens taken from the right parotid tail mass showed granulomatous inflammation with acid-fast positive bacilli; culture later confirmed M. fortuitum. After administration of clarithromycin and ciprofloxacin for 9 consecutive months, the parotitis and parotid tail mass were completely resolved at follow-up examination. CONCLUSION: To our knowledge, this is the first case report of parotitis caused by M. fortuitum and its successful medical treatment.

[Research progress in Laggera medicinal plants].

This paper reviewed the worldwide research progresses of the genus Laggera both on phytochemical and pharmacological work in the past few decades. The main secondary metabolites of this genus are proved to be sesquitepenoids, flavonoids and phenolic acids. Phamacological investigations revealed that the certain extracts of some Laggera species possess significant bioactivities on anti-inflammation, anti-tumor and anti-viral infection. This review afforded the comprehensive description of the active components as to provide useful references to elucidate their historical clinical application on upper respiratory infection, influenza, parotitis, and recurrent herpes viral infection.

Management of childhood diseases during the Byzantine period: III-- respiratory diseases of childhood.

Evidence on herbal, veterinary and chemical substances used in various forms for respiratory problems of childhood such as acute otitis, acute tonsillitis and parotitis was investigated in the Byzantine medical treatizes, from the 4th to the 15th century ad. The problem of asthma in childhood was well known during the Byzantine period. Despite the existent Hippocratic tradition, the physicians of the times developed their own methods of treatment. The texts of Antyllus, Orivasios from Pergamos, Aetius of Amida, Alexander of Tralles, Paulus Aeginitis, Theophanis Nonnos and others, strongly suggest influences from ancient Greek and Roman medicine, but at the same time indicate an original medical thought.

Use of linezolid, an oxazolidinone, in the treatment of multidrug-resistant gram-positive bacterial infections.

We report our experience with linezolid in an investigation of its use against resistant gram-positive bacterial infections. Fifteen patients who had renal failure (n=6), recent liver transplantation (n=5) or surgery (n=6), cancer (n=3), endocarditis (n=2), or human immunodeficiency virus infection (n=1), along with infections due to vancomycin-resistant enterococcus (VRE), and 2 patients with infections due to methicillin-resistant Staphylococcus species who had adverse reactions to vancomycin were treated with linezolid (600 mg every 12 h for 5-42 days (mean+/-SD, 20.5+/-3.5 days). Abscess drainage or prosthetic device removal was undertaken. Microbiological cure occurred in all 10 patients who completed therapy, and all 7 patients alive at follow-up were free of infection. No deaths were attributable to the index infection. Adverse events associated with linezolid use were mild leukopenia in 1 patient and nausea in another. It appears that administration of linezolid, in conjunction with surgical intervention or device removal, is an effective treatment option for serious resistant gram-positive bacterial infections.

[Recurrent parotitis in children and HIV infection. Apropos of 4 cases]. / Parotidites récidivantes de l'enfant et infection HIV. A propos de 4 observations.

We report four cases of recurrent infectious parotiditis in children and recall the clinical radiographic and pathogenic features. Particular attention was paid to the possible relationship between sialadenitis and HIV infection in two cases. This would open a large etiological field when HIV contamination is suspected. Treatment if all four cases (spiramycine, diclofenac, soframycin washing, lipiodol instillation and local bucco-dental treatment) was successful leading to longer intervals between relapses.

[The participation of prostaglandin F2 in the peroxidation damages and antiperoxidation protection of the parotid gland in acute nonepidemic parotitis]. / Uchastie prostaglandina F2 v perekisnykh povrezhdeniiakh i antiperekisnoi zashchite okoloushnoi sliunnoi zhelezy pri ostrom neépidemicheskom parotite.

Effects of prostaglandin F2 on the major components of the antioxidative system (levels of malonic dialdehyde and lipid peroxides, activities and content of glutathione enzymes and nonenzymes (glutathione peroxidase, glutathione reductase, and NADPH (NADH), oxidized and reduced glutathione) were studied in experiments with 60 dogs in which acute nonepidemic parotitis was modeled. A varying capacity of the cells of the parotid gland to resist the detrimental effects of the disease and specific features of prostaglandin F2 effect on this capacity were revealed: injection of prostaglandin F2 stimulated both lipid peroxidation and the activity of the antioxidative system and led to cellular injury in the presence of a relatively high level of cellular metabolism, preserving cellular viability on condition of inhibited rate of metabolic reactions, this being the principal factor for the parotid gland, among other factors determining the cytoprotective effect.

[A treatment method for chronic parenchymatous parotitis]. / Sposob lecheniia khronicheskogo parenkhimatoznogo parotita.

A method for therapy of chronic parenchymatous parotitis is suggested supplementing dimethyl sulfoxide. As reported, the parotid glands produce parotin, an insulin-like substance, whose production is reduced in chronic parotitis; hence, short-acting insulin administered in microdoses was chosen for therapy. To potentiate local insulin effect and increase the sensitivity of oral mucosa peripheral receptors to it a 5% calcium pantothenate solution was used. This method was used in the treatment of 42 patients with chronic parenchymatous parotitis aged 23 to 62. The method is effective, it can be easily used by the patients themselves, and there are virtually no contraindications against such therapy. The authors have applied for inventors' certificate, the priority certificate is No. 4836436/14 as of June 27, 1990.

[Recurrent infectious parotiditis in the child (author's transl)]. / Les parotidites infectieuses récidivantes de l'enfant.

On the basis of 18 cases of recurrent parotiditis in the child, the authors offer the current review of this condition: clinical features, radiological features, bacteriological features, course. They emphasize the importance of precise technique during sialography, which must include straight and lateral films. The progress of this condition is characterised by recurrences. These may be avoided by prolonged and appropriate antibiotic therapy. The improvement which takes place at puberty is of etiopathogenic significance. Bucco-dental septis, constantly present, is one of the causes favourising infectious parotiditis in child.