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1.
Intern Med ; 59(2): 181-192, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-31941868

RESUMEN

Objective Pneumonia develops in bedridden patients, even in those receiving oral care, and malnutrition is associated with the development of pneumonia. We examined the effects of nutritional treatment on the prevention of pneumonia. Patients and Methods We retrospectively examined the effects of nutritional treatment on the prevention of pneumonia by analyzing the records of bedridden patients (n=68; mean age: 68.0 years) who stayed in a hospital for 2 years or longer. Results Among the analyzed patients, pneumonia developed in 52 (76%) patients, and the mean frequency of pneumonia was 1.6 times per year during the first year of stay. In a multivariate analysis, the serum albumin level at admission in the pneumonia group was lower than that in the non-pneumonia group. The frequency of pneumonia during the second year of stay was lower than that during the first year of stay. Serum levels of albumin and total protein (TP) at one year after admission were higher than those at admission in all analyzed patients, and in all patients (n=52) and elderly (≥65 years) patients (n=31) in the pneumonia group. The proportions of patients with hypoalbuminemia (<3.5 g/dL) and hypoproteinemia (<6.5 g/dL) at one year after admission were lower than those at admission. The increases in the proportions of patients presenting a reduced frequency of pneumonia were correlated with increases in the proportions of patients presenting increased levels of albumin and/or TP. Conclusion Nutritional treatment may reduce the frequency of pneumonia by improving malnutrition in bedridden patients receiving oral care.


Asunto(s)
Personas Encamadas , Desnutrición/prevención & control , Apoyo Nutricional/métodos , Neumonía Bacteriana/prevención & control , Anciano , Femenino , Hospitalización , Humanos , Hipoalbuminemia/etiología , Hipoproteinemia/etiología , Masculino , Desnutrición/dietoterapia , Análisis Multivariante , Neumonía Bacteriana/dietoterapia , Estudios Retrospectivos
2.
Auris Nasus Larynx ; 47(1): 154-157, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-31280931

RESUMEN

OBJECTIVE: In the present study, we examined the effects of daily application of capsaicin ointment to the external auditory canal for 6 months on the development of pneumonia in elderly dementia patients at high risk of aspiration. METHODS: Twenty-nine oldest-old bedridden dementia inpatients at high risk of aspiration were enrolled in the present study. Ointment containing 0.025% capsaicin was applied to each external auditory canal with a cotton swab alternatively once a day for 6 months. RESULTS: The incidence of pneumonia during the 6 months before the intervention was 1.80±0.37 in these patients. However, this incidence significantly decreased to 0.40±0.29 (p<0.01) during the 6 months of the alternative application of capsaicin ointment to each auditory canal. No adverse effect such as otalgia was observed. CONCLUSION: These findings suggest that daily long-term aural stimulation with capsaicin ointment enhanced the cough reflex via Arnold's ear-cough reflex as a glottis protective measure, resulting in the reduction of incidence of pneumonia in elderly dementia patients at high risk of aspiration. The daily aural stimulation with capsaicin ointment may be a safe and promising intervention to prevent aspiration pneumonia in elderly people, especially those who cannot undergo swallowing exercise.


Asunto(s)
Capsaicina/uso terapéutico , Tos , Demencia , Conducto Auditivo Externo , Neumonía por Aspiración/prevención & control , Reflejo , Fármacos del Sistema Sensorial/uso terapéutico , Administración Tópica , Anciano , Anciano de 80 o más Años , Personas Encamadas , Femenino , Humanos , Incidencia , Masculino , Neumonía/prevención & control , Neumonía por Aspiración/epidemiología , Aspiración Respiratoria/fisiopatología , Aspiración Respiratoria/prevención & control
3.
Ann Glob Health ; 85(1): 124, 2019 10 15.
Artículo en Inglés | MEDLINE | ID: mdl-31673511

RESUMEN

Background: Liberia faces a critical shortage of palliative care services, particularly for persons with advanced-stage HIV/AIDS, tuberculosis, diabetes, and cancers. Access to healthcare services is especially limited in rural areas, along with a lack of supportive social and economic resources. Home of Dignity (HoD) Health Center was established in 2013 in Yarbah's Town to fill a last-option palliative care gap. The mission emphasizes patient wellbeing and worth. HoD integrates health, agriculture, and education on-site for immediate medical needs, broader sustainable development, and reducing disease-associated stigma in local communities. Objective: We aimed to describe the Center's integrated approach and conduct a descriptive analysis of the HoD patient population. Methods: We reviewed patient characteristics (sex, age distribution, mobility status, and CD4 count on arrival) and outcomes (survival rate and community reintegration) for patients with HIV seeking care at the Center between 2013-2017. Findings: Of 182 patients (ages 3 months-50 years), over half arrived to the facility bedridden and over 82% had CD4 counts between <100-350. Of the 182 patients, 66% survived, 27% died, and 7% were lost to follow-up. Of surviving patients, 90% were successfully reintegrated into their communities. The clinic also served over 365 chronically ill patients that had been rejected by other health providers during the 2014-2015 Ebola outbreak. Conclusions: The Center is providing last-option palliative care services in the country. As a trusted healthcare center, patients also seek care for acute conditions, resulting in unanticipated resource demands. HoD's experience underscores the need for development of training programs for medical professionals, supply chains, community outreach, and resourcing channels to ensure adequate and sustainable service provision for hospice and palliative care services and reduce stigma in the country. There is an urgent need to invest in holistic palliative and overall healthcare services in Liberia.


Asunto(s)
Integración a la Comunidad , Infecciones por VIH/tratamiento farmacológico , Accesibilidad a los Servicios de Salud , Cuidados Paliativos/organización & administración , Personeidad , Estigma Social , Adolescente , Adulto , Terapia Antirretroviral Altamente Activa , Personas Encamadas , Recuento de Linfocito CD4 , Niño , Preescolar , Femenino , Infecciones por VIH/mortalidad , Humanos , Lactante , Liberia , Perdida de Seguimiento , Masculino , Persona de Mediana Edad , Desarrollo de Programa , Población Rural , Sobrevida , Adulto Joven
4.
HU rev ; 45(4): 441-451, 2019.
Artículo en Portugués | LILACS | ID: biblio-1177336

RESUMEN

Introdução: A lesão por pressão (LPP) é um dano localizado na pele e/ou no tecido mole subjacente que ocorre normalmente em pacientes acamados, com declínio do estado nutricional e da imunidade. Portanto, tem-se, o processo de cicatrização prejudicado e o uso de alguns imunomoduladores pode melhorar esse quadro, como a arginina. Objetivo: Identificar na literatura científica o efeito e o mecanismo de ação da arginina isolada ou associada na cicatrização de LPP. Material e Métodos: Revisão sistemática da literatura científica, com pesquisas nas bases de dados PubMed, Trip Data Base, Scielo, Science Direct e Scopus entre agosto de 2018 e abril de 2019, com recorte temporal de 2008 a 2018. Foram adotados os descritores e termos de pesquisa arginina, úlcera por pressão, cicatrização e tratamento. Resultados: A busca resultou em 11 artigos que atenderam aos critérios do presente estudo. Esses evidenciaram que a suplementação de arginina, isolada ou associada a nutrientes antioxidantes, possui resultados significativos no tratamento de LPP que levam a considerável diminuição do tempo de internação e dos custos hospitalares. Conclusão: O uso de arginina isolada ou associada a nutrientes antioxidantes têm efeitos promissores na cicatrização de LPP.


Introduction: Pressure ulcer (PU) is localized damage to the skin and/or underlying soft tissue that normally occurs in hospitalized patients with declining nutritional status and immunity. Therefore, one has, the process of impaired healing and use some immunomodulators may better this picture, such as arginine. Objective: To identify in the scientific literature the effect and mechanism of action of arginine alone or associated in the healing of PU. Material and Methods: Systematic review of the scientific literature, with searches in the databases PubMed, Trip Data Base, Scielo, Science Direct and Scopus between August 2018 and April 2019, with a temporal cut from 2008 to 2018. The following descriptors and terms were adopted arginine, pressure ulcer, healing and treatment. Results: The search resulted in 11 articles that met the criteria of the present study. These evidenced that arginine supplementation, alone or associated with antioxidant nutrients, has significant results in the treatment of LPP that lead to a considerable reduction in length of stay and hospital costs. Conclusion: The use of arginine alone or associated with antioxidant nutrients has promising effects on the healing of PU.


Asunto(s)
Arginina , Arginina/efectos adversos , Piel , Cicatrización de Heridas , Úlcera por Presión , Personas Encamadas
5.
PLoS One ; 13(11): e0207174, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-30427906

RESUMEN

BACKGROUND: Pain is a universal issue and is of particular concern in mechanically ventilated patients, as they require intensive nursing care and multiple invasive procedures, while being unable to communicate verbally. The aim of this study was to assess the effect of music on pain experienced by mechanically ventilated patients during morning bed bathing. METHODS: Of the 60 mechanically ventilated patients enrolled in this single-center pilot study between March 2013 and October 2015, the first 30 received no music and the next 30 the music intervention, during the morning bed bath. The Behavioral Pain Scale (BPS) score was determined during and at the end of the bath then 30, 60, and 120 minutes after the bath. BPS score changes over time were assessed and the proportions of bath times spent with a BPS score ≥5 and with the maximal BPS score were determined. RESULTS: At baseline, no patient had pain (defined as a BPS score <5) and the median BPS score was 3 [IQR, 3;3] in both groups (P = 0.43). After bed bath initiation, 88% of patients experienced pain. The maximum BPS value during the bath was lower in the music group (5 [5;6.7] vs. 7 [5;7]). Proportions of total bath time spent with BPS≥5 and with the maximum BPS were significantly lower in the music group than in the control group (2.0 [0.3;4.0] vs. 10 [4.3;18.0]; P < .0001 and 1.5 [0;3.0] vs. 3.5 [2.0;6.0]; P = .005; respectively). Two hours after the end of the bath, the BPS values had returned to baseline in both groups. CONCLUSION: In our population, music significantly decreased pain intensity and duration during the morning bed bath in mechanically ventilated patients. These results warrant further assessment in a large multicenter randomized controlled trial. TRIAL REGISTRATION: ClinicalTrials.gov NCT02883959.


Asunto(s)
Baños/efectos adversos , Musicoterapia/métodos , Manejo del Dolor/métodos , Respiración Artificial/efectos adversos , Anciano , Anciano de 80 o más Años , Personas Encamadas , Cuidados Críticos , Femenino , Francia , Humanos , Unidades de Cuidados Intensivos , Masculino , Persona de Mediana Edad , Dolor/etiología , Dolor/fisiopatología , Dimensión del Dolor , Proyectos Piloto , Estudios Prospectivos
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