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1.
Proc Inst Mech Eng H ; 222(3): 393-402, 2008 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-18491707

RESUMEN

Approximately 50 child sarcomas are treated with limb salvage surgery each year in the United Kingdom. These children need an extendable implant that can be lengthened periodically to keep pace with the growth in the opposite limb. Surgically, invasive devices have been used for the past 30 years with intrinsic problems of infection and long-term recurrent trauma to the patient. To eliminate problems associated with the invasive device, a noninvasive extendable prosthesis was developed. The magnetically coupled drive technology used for this prosthesis was a synchronous motor with a gear-driven telescoping shaft. In this design the motor configuration was in two parts: a rotating magnet (rotor) that fitted inside the prosthesis where space was limited and the stator, which was an external device used to extend the prosthesis remotely as the patient grew. This compact external drive produced a focused magnetic flux that required no cooling and operated on a single-phase power supply. The extending mechanism in the implant was able to overcome up to 1300 N force, which is the tension force exerted by the soft tissues during the lengthening procedure. The device has been successfully implanted in 50 patients.


Asunto(s)
Neoplasias Óseas/rehabilitación , Magnetismo/instrumentación , Magnetismo/uso terapéutico , Diseño de Prótesis , Dispositivos de Expansión Tisular , Adolescente , Ingeniería Biomédica/métodos , Neoplasias Óseas/cirugía , Niño , Análisis de Falla de Equipo , Humanos , Recuperación del Miembro/rehabilitación , Implantación de Prótesis , Expansión de Tejido/instrumentación
2.
Ann Surg Oncol ; 9(1): 41-7, 2002.
Artículo en Inglés | MEDLINE | ID: mdl-11829429

RESUMEN

BACKGROUND: Lower-extremity tumors are often treated by amputation rather than limb-sparing excision that sacrifices the sciatic nerve or a branch. This study assessed the functional outcome of major nerve sacrifice during limb-sparing resections for lower-extremity soft tissue sarcoma. METHODS: Patients who underwent division of the sciatic, tibial, or peroneal nerve(s) during limb-sparing sarcoma surgery (January 1982 through June 2000) were identified. Eleven surviving patients evaluated their pre- and postoperative functional status by self-administered questionnaire (six sciatic, two tibial, and three peroneal nerve divisions). RESULTS: Eighteen patients (10 male, 8 female; 14-84 years old) had nine primary and nine locally recurrent tumors. Tumors were high (16) or low grade (two). Five patients died of disease and two died of other causes. Median overall survival was 50 months. One of 11 reported increased pain. Eight had new phantom sensations with a median intensity of 4.5 (1 = least; 10 = most). All patients used an ankle brace to walk after a sciatic (four) or peroneal (one) division. Walking ability and distance after surgery was unchanged (nine), improved (one), and worsened (one). Standing improved in 7 of 11 patients. Proprioception in the affected extremity was retained in six. The median postoperative leg functional score was 8 (1 = worst; 10 = best). No patient developed foot ulcers. One patient underwent amputation for recurrence. All patients preferred their status over having an amputation. CONCLUSIONS: Objectively and subjectively, division of the major lower-extremity nerves causes acceptable functional deficits in most patients. Resection of affected sciatic nerve (branches) during limb-sparing tumor surgery is an excellent alternative to amputation.


Asunto(s)
Desnervación , Recuperación del Miembro , Nervio Peroneo/cirugía , Sarcoma/cirugía , Nervio Ciático/cirugía , Nervio Tibial/cirugía , Adolescente , Adulto , Anciano , Desnervación/efectos adversos , Desnervación/rehabilitación , Femenino , Humanos , Pierna/inervación , Pierna/fisiopatología , Recuperación del Miembro/métodos , Recuperación del Miembro/rehabilitación , Masculino , Persona de Mediana Edad , Calidad de Vida , Recuperación de la Función , Estudios Retrospectivos , Sarcoma/rehabilitación , Autoevaluación (Psicología) , Resultado del Tratamiento
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