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1.
Nutrients ; 14(2)2022 Jan 14.
Artículo en Inglés | MEDLINE | ID: mdl-35057537

RESUMEN

BACKGROUND AND OBJECTIVES: Neural tube defects are congenital anomalies which canlead to infant death and serious disability. They are initiated during embryogenesis, between the 23rd and 27th day of fetal life, and can be prevented by the administration of folic acid. Therefore, this study aims to evaluate the knowledge and practice of Saudi women at childbearing age regarding NTDs and FA supplementation. METHODOLOGY: This is a cross-sectional study on Saudi women of reproductive age who were asked to complete an online survey to examine their knowledge and practice regarding folic acid supplementation and neural tube defects. Descriptive and simple linear regression analyses were conducted using SPSS v.26 (SPSS Inc., Chicago, IL, USA). RESULTS: A total of 613 women have completed the questionnaire, from which the majority (46.7%) were aged between 36 and 40 years. About 94% of women heard about folic acid and 80% indicated that its deficiency has some relation to neural tube defects. Approximately 37%, 25.3%, and 23.2% of women reported the proper time for folic acid intake to be during first trimester of pregnancy, before pregnancy, or throughout pregnancy, respectively. Linear regression analysis revealed that increase age and education were significantly correlated with a decrease in folic acid administration (p = 0.008) and (p = 0.001), respectively. However, there was no association between time of folic acid administration and income or number of parities. CONCLUSION: Despite the acceptable level of awareness about the relation of folic acid and neural tube defects, our results revealed that more education is required towards the proper time of supplementation among Saudi childbearing women.


Asunto(s)
Suplementos Dietéticos , Ácido Fólico/uso terapéutico , Conocimientos, Actitudes y Práctica en Salud , Terapia Nutricional/psicología , Atención Preconceptiva , Adulto , Factores de Edad , Estudios Transversales , Escolaridad , Femenino , Humanos , Embarazo , Atención Prenatal/psicología , Salud Reproductiva/estadística & datos numéricos , Arabia Saudita , Encuestas y Cuestionarios , Adulto Joven
2.
Nutrients ; 13(11)2021 Oct 27.
Artículo en Inglés | MEDLINE | ID: mdl-34836086

RESUMEN

There is increasing recognition of the importance of nutrition for reproductive health, but little is known regarding the diet quality of younger vs. older reproductive aged women, and how their intakes relate to dietary recommendations. The purpose of the study was to examine the diets of younger (19-35 years old) compared to older (35-50 years old) reproductive aged women, and how they align with dietary recommendations. Women aged 19-50 years from the 2011-13 Australian National Nutrition and Physical Activity Survey were included (n = 2323). Dietary intakes were assessed by a single 24-h dietary recall and were compared to (i) Australian Dietary Guidelines; (ii) Acceptable Macronutrient Distribution for protein, carbohydrates, and fat; and (iii) Dietary Guideline Index (DGI). Regression analyses comparing younger and older women against recommendations were undertaken, with confounders determined a priori. There was no difference between older and younger women in meeting food group recommendations, with 26% of all women meeting recommendations for fruit, and meat and alternatives, and <20% meeting recommendations for vegetables and alternatives, grains, and dairy. Although there was no difference between older and younger women in total DGI score (mean (SE) 75.6 (1.7) vs. 74.5 (2.5), p > 0.05), older women had higher component scores in limiting saturated fat, consuming low-fat milk, and limiting adding salt during cooking. Continued health promotion for women of reproductive age should be a key priority to improve their own health and that of future generations.


Asunto(s)
Factores de Edad , Dieta Saludable/estadística & datos numéricos , Salud Reproductiva/estadística & datos numéricos , Adulto , Australia , Ingestión de Alimentos , Conducta Alimentaria , Femenino , Encuestas Epidemiológicas , Humanos , Persona de Mediana Edad , Política Nutricional , Estado Nutricional , Adulto Joven
3.
Nutrients ; 13(7)2021 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-34371796

RESUMEN

Overlapping micronutrient interventions might increase the risk of excessive micronutrient intake, with potentially adverse health effects. To evaluate how strategies currently implemented in Benin and Ghana contribute to micronutrient intake in women of reproductive age (WRA), and to assess the risk for excess intakes, scenarios of basic rural and urban diets were built, and different on-going interventions were added. We estimated micronutrient intakes for all different scenarios. Four types of intervention were included in the scenarios: fortification, biofortification, supplementation and use of locally available nutrient-rich foods. Basic diets contributed poorly to daily micronutrient intake in WRA. Fortification of oil and salt were essential to reach daily requirements for vitamin A and iodine, while fortified flour contributed less. Biofortified products could make an important contribution to the coverage of vitamin A needs, while they were not sufficient to cover the needs of WRA. Iron and folic acid supplementation was a major contributor in the intake of iron and folate, but only in pregnant and lactating women. Risk of excess were found for three micronutrients (vitamin A, folic acid and niacin) in specific contexts, with excess only coming from voluntary fortified food, supplementation and the simultaneous overlap of several interventions. Better regulation and control of fortification and targeting of supplementation could avoid excess intakes.


Asunto(s)
Micronutrientes/análisis , Terapia Nutricional/estadística & datos numéricos , Hipernutrición/etiología , Salud Reproductiva/estadística & datos numéricos , Salud de la Mujer/estadística & datos numéricos , Adolescente , Adulto , Benin/epidemiología , Biofortificación/estadística & datos numéricos , Simulación por Computador , Dieta/estadística & datos numéricos , Suplementos Dietéticos/estadística & datos numéricos , Ingestión de Alimentos , Femenino , Ácido Fólico/análisis , Alimentos Fortificados/estadística & datos numéricos , Ghana/epidemiología , Humanos , Persona de Mediana Edad , Niacina/análisis , Terapia Nutricional/efectos adversos , Terapia Nutricional/métodos , Estado Nutricional , Hipernutrición/epidemiología , Embarazo , Ingesta Diaria Recomendada , Factores de Riesgo , Población Rural/estadística & datos numéricos , Población Urbana/estadística & datos numéricos , Vitamina A/análisis , Adulto Joven
4.
J Prev Med Public Health ; 53(5): 353-361, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-33070507

RESUMEN

OBJECTIVES: An inadequate understanding of infertility can affect individuals' self-efficacy and ability to perform self-care; thus, reproductive health education is an important part of infertility treatment. The present qualitative study aimed to explore the experiences and educational needs of infertile women with regard to reproductive health. METHODS: In this qualitative study, we utilized a content analysis approach. Purposive sampling was performed to ensure maximum diversity. In total, 23 individual interviews were conducted with 20 Iranian women with infertility and 3 key informants between July 2018 and February 2019 in northern Iran. Data were collected through in-depth, semi-structured interviews. Data analysis was performed using a conventional content analysis approach. RESULTS: Reproductive health education needs were identified by analyzing interview data from 4 main categories: familiarity with the fertility process and preparation for pregnancy, recognition of infertility and expectations around seeking treatment, recognition of preventive actions associated with reproductive health, and correction of false beliefs. Recognizing the causes of infertility and understanding the different approaches to infertility treatment are among the most important educational needs of infertile women. The potential for neglect of health-related issues due to concerns about fertility and the maternal experience necessitates education about preventive measures for cervical cancer, breast cancer, and sexually transmitted infections. Correcting misconceptions, including those related to contraceptives and traditional medicine, can also help promote reproductive health. CONCLUSIONS: In infertile women, the educational needs associated with reproductive health are multifaceted. Satisfying these needs can help achieve optimal treatment results and promote reproductive health.


Asunto(s)
Infertilidad/fisiopatología , Infertilidad/terapia , Evaluación de Necesidades/estadística & datos numéricos , Salud Reproductiva/educación , Adulto , Escolaridad , Femenino , Alfabetización en Salud , Humanos , Irán , Persona de Mediana Edad , Embarazo , Investigación Cualitativa , Salud Reproductiva/estadística & datos numéricos
5.
J Altern Complement Med ; 26(11): 1000-1014, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-32609536

RESUMEN

Objectives: This scoping review aims to (1) describe the scope and coverage of the body of literature on nonbiomedical practices used for enhancing fertility, (2) summarize and map the existing evidence on the extent and types of nonbiomedical practices used, and (3) examine how the research on this topic has been conducted with particular attention paid to how participants are asked about their use of nonbiomedical practices for fertility enhancement. Design: We conducted a scoping review by which four databases were searched (PubMed, Psychinfo, Socindex, and CINHAL). Articles were screened for inclusion by two researchers through a title and abstract screening followed by a full-text screening. Data were extracted from included articles and results summarized and compared across studies and regions. Results: A total of 32 studies were identified from 16 countries in five regions of the world. The majority of studies were clinic-based, primarily recruiting participants from fertility clinics in urban and suburban areas. More than half of the studies included only women, a few studies included only men, and the remainder of studies included both men and women. Most quantitative studies reported the prevalence of nonbiomedical practice use, which ranged from 8% to 83%; however, there was variation across studies regarding the time frame for which these percentages were derived. Few studies reported on other measures of the extent of use such as duration or frequency. A variety of nonbiomedical practices were identified with biologically based treatments, particularly herbal medicine use, being the most common followed by religious and spiritual interventions. Regional differences were identified. Variation in the wording and format of the question(s) used in survey instruments asking participants about their use of nonbiomedical practices exists and may impact participants' reporting of use. Conclusions: Infertility affects millions of individuals worldwide often with severe social, emotional, and financial consequences. To enhance fertility and, in some cases, overcome infertility, many individuals and couples are engaging in a variety of nonbiomedical practices. This scoping review describes the scope and nature of the existing literature on the use of nonbiomedical practices for fertility enhancement and highlights important gaps and limitations in the conduct of this research. A more comprehensive and inclusive investigation of nonbiomedical practices for enhancing fertility is needed to improve our understanding of how individuals and couples are managing infertility, identify educational and counseling needs, and to improve research related to effectiveness and safety of nonbiomedical practices.


Asunto(s)
Terapias Complementarias/estadística & datos numéricos , Práctica Clínica Basada en la Evidencia , Infertilidad/terapia , Salud Reproductiva/estadística & datos numéricos , Adulto , Femenino , Humanos , Infertilidad/prevención & control
6.
Trop Med Int Health ; 25(1): 70-80, 2020 01.
Artículo en Inglés | MEDLINE | ID: mdl-31692194

RESUMEN

OBJECTIVES: We analysed mutually comparable surveys on adolescent attitudes and behaviours from nine sites in seven sub-Saharan African countries, to determine the relationship between school enrolment and adolescent health outcomes. METHODS: Data from the Africa Research, Implementation Science, and Education Network cross-sectional adolescent health surveys were used to examine the associations of current school enrolment, self-reported general health and four major adolescent health domains: (i) sexual and reproductive health; (ii) nutrition and non-communicable diseases; (iii) mental health, violence and injury; and (iv) healthcare utilisation. We used multivariable Poisson regression models to calculate relative risk ratios with 95% confidence intervals (CI), controlling for demographic and socio-economic characteristics. We assessed heterogeneity by gender and study site. RESULTS: Across 7829 adolescents aged 10-19, 70.5% were in school at the time of interview. In-school adolescents were 14.3% more likely (95% CI: 6-22) to report that their life is going well; 51.2% less likely (95% CI: 45-67) to report ever having had sexual intercourse; 32.6% more likely (95% CI: 9-61) to report unmet need for health care; and 30.1% less likely (95% CI: 15-43) to report having visited a traditional healer. School enrolment was not significantly associated with malnutrition, low mood, violence or injury. Substantial heterogeneity was identified between genders for sexual and reproductive health, and in-school adolescents were particularly less likely to report adverse health outcomes in settings with high average school enrolment. CONCLUSIONS: School enrolment is strongly associated with sexual and reproductive health and healthcare utilisation outcomes across nine sites in sub-Saharan Africa. Keeping adolescents in school may improve key health outcomes, something that can be explored through future longitudinal, mixed-methods, and (quasi-)experimental studies.


OBJECTIFS: Nous avons analysé des enquêtes mutuellement comparables sur les attitudes et les comportements d'adolescents dans neuf sites dans sept pays d'Afrique subsaharienne, afin de déterminer la relation entre la scolarisation et les résultats de la santé des adolescents. MÉTHODES: Des données provenant d'enquêtes transversales sur la santé des adolescents menées par le Réseau Africain de Recherche, d'Implémentation, de Science et d'Education ont été utilisées pour examiner les associations existant entre la scolarisation, l'état de santé général autodéclaré et les quatre principaux domaines de la santé des adolescents: (i) santé sexuelle et reproductive ; (ii) nutrition et maladies non transmissibles; (iii) santé mentale, violence et blessures et (iv) utilisation des soins de santé. Nous avons utilisé des modèles de régression multivariée de Poisson pour calculer les rapports de risque relatifs avec des intervalles de confiance (IC) à 95%, en tenant compte des caractéristiques démographiques et socioéconomiques. Nous avons évalué l'hétérogénéité par sexe et par site d'étude. RÉSULTATS: Sur 7.829 adolescents âgés de 10 à 19 ans, 70,5% étaient à l'école au moment de l'enquête. Les adolescents scolarisés étaient 14,3% (IC95%: 6-22) plus susceptibles de déclarer que leur vie se passait bien, 51,2% (IC95%: 45-67) moins susceptibles de déclarer avoir déjà eu des rapports sexuels, 32,6% (IC95%: 39-91) plus susceptibles de signaler un besoin de soins de santé non satisfait et 30,1% (IC95%: 15-43) moins susceptibles de déclarer avoir rendu visite à un guérisseur traditionnel. La scolarisation n'était pas associée de manière significative à la malnutrition, à la mauvaise humeur, à la violence ou aux blessures. Une hétérogénéité substantielle a été identifiée entre les sexes pour la santé sexuelle et reproductive, et les adolescents scolarisés étaient particulièrement moins susceptibles de faire état de résultats défavorables pour la santé dans les milieux où la moyenne de scolarisation était élevée. CONCLUSIONS: La scolarisation est fortement associée aux résultats en matière de santé sexuelle et reproductive et d'utilisation des soins de santé dans neuf sites en Afrique subsaharienne. Garder les adolescents à l'école peut améliorer les principaux résultats de santé, ce qui peut être exploré dans le cadre de futures études longitudinales.


Asunto(s)
Estado de Salud , Salud Mental/estadística & datos numéricos , Salud Reproductiva/estadística & datos numéricos , Salud Sexual/estadística & datos numéricos , Abandono Escolar/estadística & datos numéricos , Adolescente , Salud del Adolescente , África del Sur del Sahara/epidemiología , Factores de Edad , Niño , Estudios Transversales , Femenino , Humanos , Entrevistas como Asunto , Masculino , Enfermedades no Transmisibles/epidemiología , Estado Nutricional , Aceptación de la Atención de Salud/estadística & datos numéricos , Factores Sexuales , Factores Socioeconómicos , Violencia/estadística & datos numéricos , Adulto Joven
7.
PLoS One ; 14(11): e0224229, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31730622

RESUMEN

Adequate iodine status of women of childbearing age is essential for optimal growth and development of their offspring. The objectives of the current study were to assess the iodine status of non-pregnant women, availability and use of commercial salt, extent to which it is iodised, and availability of other industrially processed foods suitable for fortification with iodine. This prospective cross-sectional study was carried out in 2018 in a remote area in Gulf province, Papua New Guinea. Multistage cluster sampling was used to randomly select 300 women visiting local markets. Of these, 284 met study criteria of being non-pregnant and non-lactating. Single urine samples were collected from each of them. Discretionary salt intake was assessed; salt samples were collected from a sub-sample of randomly selected households. A semi-structured, pre-tested questionnaire to assess use and availability of commercial salt and other processed foods was modified and used. Salt was available on the interview day in 51.6% of households. Mean iodine content in household salt samples was 37.8 ± 11.8 ppm. Iodine content was below 30.0 ppm in 13.1% and below 15.0 ppm in 3.3% of salt samples. Mean iodine content of salt available at markets was 39.6 ± 0.52 ppm. Mean discretionary intake of salt per capita per day was 3.9 ± 1.21 g. Median UIC was 34.0 µg/L (95% CI, 30.0-38.0 ppm), indicating moderate iodine deficiency. For women with salt in the household, median UIC was 39.5 µg/L (95% CI, 32.0-47.0 µg/L), compared to median UIC of 29.0 µg/L (95% CI, 28.0-32.0 µg/L) for those without salt. This community has low consumption of iodised salt, likely due to limited access. Investigation of other industrially processed foods indicated salt is the most widely consumed processed food in this remote community, although 39.8% of households did use salty flavourings.


Asunto(s)
Alimentos Fortificados/provisión & distribución , Yodo/orina , Estado Nutricional , Salud Reproductiva/estadística & datos numéricos , Salud de la Mujer/estadística & datos numéricos , Adolescente , Adulto , Estudios Transversales , Femenino , Alimentos Fortificados/análisis , Humanos , Yodo/administración & dosificación , Yodo/deficiencia , Papúa Nueva Guinea , Estudios Prospectivos , Cloruro de Sodio Dietético/análisis , Adulto Joven
8.
BMC Public Health ; 19(Suppl 1): 604, 2019 May 29.
Artículo en Inglés | MEDLINE | ID: mdl-31138182

RESUMEN

BACKGROUND: With a human immunodeficiency virus (HIV) prevalence of 2.1% among 15-24 year olds, opportunities for further integration of sexual and reproductive health (SRH) and HIV prevention services for young people in Uganda exist. We examine a range of factors that contribute to variance in risky sexual behaviour among young Ugandans. METHODS: A cross-sectional, nationally representative household survey was conducted between February and March 2016. The questionnaire used assessed knowledge, attitudes and practices related to SRH among young people aged 10-24 years. A composite indicator was constructed to assess risky sexual behaviour, defined as being involved in sexual relations under the influence of alcohol or drugs, engaging in sexual activities without a condom, and having multiple sexual partners in the 6 months preceding the survey. Exploratory analysis was conducted to provide descriptive statistics. Logistic regression was conducted to determine the factors associated with risky sexual behaviour. This analysis focuses on the sub-category aged 15-24 years, comprised of 2725 respondents. RESULTS: Knowledge levels of family planning (FP), sexually transmitted infections (STIs) and HIV across all respondents were high (above 82%). Self-reported perceived risk of STIs and pregnancy was consistently higher among 20-24 year old respondents, with 61.5% feeling at risk of STIs compared to 46.2% of 15-19 year olds. A total of 22.7% of respondents reported having been involved in risky sexual behaviour. Factors associated with risky sexual behaviour among the 15-19 years group included gender, single orphanhood, casual work, schooling status, FP knowledge and self-perceived risk of STIs/HIV. For the 20-24 year old respondents, significantly associated factors included gender, educational level, relationship to head of household, place of residence, and self-perceived risk of pregnancy. CONCLUSIONS: Despite high general SRH/HIV knowledge and perceived risk of pregnancy and HIV, risky sexual behaviour among young Ugandans remains high. Effectiveness gaps in the integrated SRH/HIV response for young people should be addressed and targeted interventions focused on holistic prevention at individual level through information, risk awareness, and skill development should be combined with interventions targeting social structures affecting individual behaviour.


Asunto(s)
Infecciones por VIH/psicología , Conocimientos, Actitudes y Práctica en Salud , Salud Reproductiva/estadística & datos numéricos , Salud Sexual/estadística & datos numéricos , Enfermedades de Transmisión Sexual/psicología , Adolescente , Población Negra , Niño , Condones/estadística & datos numéricos , Estudios Transversales , Femenino , VIH , Infecciones por VIH/prevención & control , Conductas de Riesgo para la Salud , Humanos , Modelos Logísticos , Masculino , Embarazo , Autoinforme , Educación Sexual , Enfermedades de Transmisión Sexual/prevención & control , Enfermedades de Transmisión Sexual/virología , Encuestas y Cuestionarios , Uganda , Adulto Joven
9.
Artículo en Inglés, Portugués | LILACS | ID: biblio-906233

RESUMEN

Este estudo apresenta um sumário das intervenções realizadas no âmbito do setor público e os indicadores de resultado alcançados na saúde de mulheres e crianças, destacando-se os avanços no período 1990-2015. Foram descritos indicadores de atenção pré-natal, assistência ao parto e saúde materna e infantil utilizando dados provenientes de Sistemas de Informação Nacionais de nascidos vivos e óbitos; inquéritos nacionais; e publicações obtidas de diversas outras fontes. Foram também descritos os programas governamentais desenvolvidos para a melhoria da saúde das mulheres e das crianças, bem como outros intersetoriais para redução da pobreza. Houve grande queda nas taxas de fecundidade, universalização da atenção pré-natal e hospitalar ao parto, aumento do acesso à contracepção e aleitamento materno, e diminuição das hospitalizações por aborto e da subnutrição. Mantém-se em excesso a sífilis congênita, taxa de cesarianas e nascimentos prematuros. A redução na mortalidade na infância foi de mais de 2/3, mas não tão marcada no componente neonatal. A razão de mortalidade materna decresceu de 143,2 para 59,7 por 1000 NV. Embora alguns poucos indicadores tenham demonstrado piora ou mantido a estabilidade, a grande maioria apresentou acentuadas melhoras.(AU)


This study presents an overview of public sector interventions and progress made on the women's and child health front in Brazil between 1990 and 2015. We analyzed indicators of antenatal and labor and delivery care and maternal and infant health status using data from the Live Birth Information System and Mortality Information System, national surveys, published articles, and other sources. We also outline the main women's and child health policies and intersectoral poverty reduction programs. There was a sharp fall in fertility rates; the country achieved universal access to antenatal and labor and delivery care services; access to contraception and breastfeeding improved significantly; there was a reduction in hospital admissions due to abortion and in malnutrition. The rates of congenital syphilis, caesarean sections and preterm births remain excessive. Under-five mortality decreased by more than two-thirds, but less pronounced for the neonatal component. The maternal mortality ratio decreased from 143.2 to 59.7 per 100 000 live births. Despite worsening scores or levelling off across certain health indicators, the large majority improved markedly.(AU)


Asunto(s)
Sistema Único de Salud , Servicios de Salud del Niño/estadística & datos numéricos , Estadísticas Vitales , Salud Reproductiva/estadística & datos numéricos , Política de Salud , Servicios de Salud Materna/estadística & datos numéricos , Brasil , Programas Nacionales de Salud
10.
Matern Child Health J ; 21(5): 1147-1155, 2017 05.
Artículo en Inglés | MEDLINE | ID: mdl-28078529

RESUMEN

Objectives Preconception care aims to provide care to reproductive aged individuals in order to improve pregnancy and birth outcomes. Given that preconception care is a public health priority, it is important to evaluate the evolution of this health paradigm and the promotion of preconception messages that are obtained by the public. We identified online preconception health messages, which were critically assessed through a women's health perspective. Methods We searched for "preconception care" on three major search engines. Websites were included if they were U.S.-based, provided content in English, and mentioned preconception care. Blogs and journal articles were excluded. The final sample included 52 websites. Using a content analysis approach, we assessed the presence of gender bias and identified other emergent themes. Results The majority of websites focused on preconception care for women only (67%). The recommendations centered on: (1) health behaviors for women (e.g., folic acid, drinking, smoking); (2) visiting healthcare providers; and (3) evaluating medical risks. Moreover, most content implied that women desired, or should desire, pregnancy. Overall, the messages used biomedical language and rarely mentioned other important health topics, such as social support and violence. Conclusions The primary messages presented on preconception care websites emphasized biomedical aspects of women's health. The current context of preconception care medicalizes this pre-pregnancy period by defining it as a biomedical condition requiring lifestyle changes and interventions. Additionally, the biases presented in these messages assumed women want and are capable of pregnancies and excluded an integral factor for heteronormative reproduction-men.


Asunto(s)
Promoción de la Salud/métodos , Servicios de Salud Materna/estadística & datos numéricos , Atención Preconceptiva/métodos , Salud Reproductiva/normas , Adulto , Femenino , Promoción de la Salud/normas , Promoción de la Salud/estadística & datos numéricos , Conducta de Búsqueda de Ayuda , Humanos , Internet , Embarazo , Complicaciones del Embarazo/prevención & control , Salud Reproductiva/estadística & datos numéricos , Motor de Búsqueda/métodos , Sexismo/estadística & datos numéricos
11.
Dan Med J ; 63(1): B5196, 2016 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-26726909

RESUMEN

INTRODUCTION: Thyroid disorders are common with occurrence primarily determined by the availability of dietary iodine. Iodine fortification programmes are internationally recommended to ensure sufficient iodine intake in populations. An understanding of the role of thyroid hormone levels within the normal range, set points and etiological factors related to thyroid disease development is important for optimal prevention and treatment. Limited data, however, exist regarding the impact of iodine fortification on thyroid function development. Additionally, the relation between body weight and thyrotropin (TSH) within the normal range and the role of female reproductive factors in the etiology of thyroid autoimmunity is debated. OBJECTIVE: The aim of this PhD project was to analyse the effect of a nationwide iodine fortification programme on individual development in thyroid function and to identify concurrent determinants for the possible changes. Furthermore, we aimed to investigate the association between weight and serum TSH change as well as the association between female reproductive factors and change in TSH and thyroid peroxidase antibody (TPO-Ab) status.    METHODS: A longitudinal population-based study of the DanThyr C1 cohort examined before (1997-1998) and after (2008-2010) the introduction of mandatory iodine fortification of salt on July 1 2000. A total of 2,465 individuals participated in the follow-up examination. The main outcome measure was change in serum TSH. Change in TPO-Ab status was additionally used in Paper III.  RESULTS: Urinary iodine excretion levels increased significantly during follow-up. Serum TSH also increased significantly, most pronounced in the region with the highest iodine intake, whereas the increase was not significant in the low-iodine-intake region. The presence of TPO-Ab at baseline and absence of goitre and multiple nodules were identified as determinants of TSH increase. Moreover, a low-normal TSH at baseline was a determinant of future decreased serum TSH, while likewise a high-normal baseline TSH values determined a TSH above normal reference range at follow-up. A positive association between 11-year serum TSH change and weight change was found, but without baseline body mass index being a determinant of future weight change and without baseline TSH being a determinant of future weight change. An inverse association between the time on HRT treatment and the risk of increased TPO-Ab status during follow-up was found, but the association was not significant when applying the Bonferroni adjusted significance level and not associated with TSH change. Parity, OCP use, abortions, age at menarche and menopausal status were associated neither with TSH change nor with increased TPO-Ab status during follow-up. CONCLUSION: TSH increased significantly, and the difference be-tween regions with different iodine intakes could indicate that iodine, at least partly, explains the TSH increase. The identified determinants of TSH change may indicate that susceptible individuals were subject to well-known adverse effects of iodine fortification. The predictive value of TSH on future TSH levels suggests a gradual development of thyroid disease. Whether body weight and TSH are causally connected remains to be proven. These results are an important contribution to the discussion of the role of thyroid hormones level within the normal range, set points and the association with body weight. A minor role, if any, is suggested for the studied female reproductive factors in development of thyroid autoimmunity. The longitudinal study neither solves the problem of causality nor is of the optimal design to measure the impact of iodization of salt, but can be informative in the study of determinants.


Asunto(s)
Alimentos Fortificados , Yodo , Enfermedades de la Tiroides , Tirotropina/sangre , Adulto , Anciano , Índice de Masa Corporal , Dinamarca/epidemiología , Femenino , Alimentos Fortificados/efectos adversos , Alimentos Fortificados/estadística & datos numéricos , Humanos , Yodo/metabolismo , Yodo/farmacología , Estudios Longitudinales , Masculino , Persona de Mediana Edad , Prevalencia , Evaluación de Programas y Proyectos de Salud , Salud Reproductiva/estadística & datos numéricos , Factores Sexuales , Enfermedades de la Tiroides/sangre , Enfermedades de la Tiroides/diagnóstico , Enfermedades de la Tiroides/epidemiología , Enfermedades de la Tiroides/etiología , Oligoelementos/metabolismo , Oligoelementos/farmacología
12.
PLoS One ; 11(1): e0146694, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-26800517

RESUMEN

BACKGROUND: The body of knowledge on evaluating complex interventions for integrated healthcare lacks both common definitions of 'integrated service delivery' and standard measures of impact. Using multiple data sources in combination with statistical modelling the aim of this study is to develop a measure of HIV-reproductive health (HIV-RH) service integration that can be used to assess the degree of service integration, and the degree to which integration may have health benefits to clients, or reduce service costs. METHODS AND FINDINGS: Data were drawn from the Integra Initiative's client flow (8,263 clients in Swaziland and 25,539 in Kenya) and costing tools implemented between 2008-2012 in 40 clinics providing RH services in Kenya and Swaziland. We used latent variable measurement models to derive dimensions of HIV-RH integration using these data, which quantified the extent and type of integration between HIV and RH services in Kenya and Swaziland. The modelling produced two clear and uncorrelated dimensions of integration at facility level leading to the development of two sub-indexes: a Structural Integration Index (integrated physical and human resource infrastructure) and a Functional Integration Index (integrated delivery of services to clients). The findings highlight the importance of multi-dimensional assessments of integration, suggesting that structural integration is not sufficient to achieve the integrated delivery of care to clients--i.e. "functional integration". CONCLUSIONS: These Indexes are an important methodological contribution for evaluating complex multi-service interventions. They help address the need to broaden traditional evaluations of integrated HIV-RH care through the incorporation of a functional integration measure, to avoid misleading conclusions on its 'impact' on health outcomes. This is particularly important for decision-makers seeking to promote integration in resource constrained environments.


Asunto(s)
Prestación Integrada de Atención de Salud/métodos , Infecciones por VIH/terapia , Modelos Organizacionales , Servicios de Salud Reproductiva/estadística & datos numéricos , Salud Reproductiva/estadística & datos numéricos , Esuatini , Femenino , Humanos , Kenia , Masculino , Modelos Estadísticos
13.
Enferm. glob ; 14(37): 455-466, ene. 2015. ilus
Artículo en Español | IBECS | ID: ibc-131086

RESUMEN

Introducción: En España en el año 2013 había un total de 6.259.137 extranjeros, el 49% eran mujeres, esto da lugar a que la salud reproductiva de este colectivo suponga una preocupación importante en el campo de la Salud Pública en España, ya que es uno de los grupos más demandantes de determinados servicios sanitarios. Objetivo: Describir la situación actual del empleo de métodos anticonceptivos de la mujer inmigrante en España en los últimos años (2005 en adelante). Metodología: Se realizó una revisión bibliográfica en la primera quincena de marzo de 2014, se limitó a artículos y revisiones bibliográficas publicadas a partir del 2005 en inglés y español. Las bases de datos utilizadas fueron PubMed, IME, SCOPUS, CINAHL, CUIDEN, WOS, Cochrane Library y TESEO. Resultados: La enfermera juega un papel fundamental en el conocimiento y uso de nuevos métodos anticonceptivos por parte de la mujer inmigrante, contando con que el DIU es más utilizado por la inmigrante magrebí y de Europa del Este, el preservativo es el más usado por la inmigrante latinoamericana, la asiática conoce bien todos los métodos pero prefiere la medicina tradicional china, y la subsahariana es la que tiene menor índice de uso de métodos anticonceptivos. Conclusiones: Existe una variabilidad de métodos anticonceptivos por parte de la mujer inmigrante en España según su religión y/o cultura. El profesional de Enfermería, debe conocer dichas peculiaridades, con el fin de ofrecer un cuidado transcultural a la paciente y su pareja al objeto de favorecer una planificación familiar efectiva (AU)


Introduction: There were a total of 6,259,137 foreigners in Spain in 2013, 49% of which were women. This leads to the reproductive health of this collective supposing an important problem in the field of Public Health in Spain, since it is one of the most demanding groups in certain health services. Objective: To describe the current situation of contraceptive methods of immigrant women in Spain in recent years (2005 onwards). Methodology: A literature review was conducted in the first half of March 2014, it was limited to articles and literature reviews published since 2005 in English and Spanish. The databases used were PubMed, IME, SCOPUS, CINAHL, CUIDEN, WOS, Cochrane Library and TESEO databases. Results: The nurse plays a key role in the knowledge and use of new contraceptive methods by immigrant women, with the IUD being used by Maghrebi and Eastern European immigrants, the condom is the most used by the Latino immigrants, Asians know all the methods but prefer the traditional Chinese medicine, while the Sub-Saharan is the one who has the lowest rates of contraceptive use. Conclusions: The variability of contraceptive methods used by immigrant women in Spain depends on their religion and/or culture. The nursing professional must know these peculiarities, in order to provide a transcultural care to the patient and her partner in order to promote effective family planning (AU)


Asunto(s)
Humanos , Femenino , Anticonceptivos , Anticonceptivos Femeninos/uso terapéutico , Dispositivos Anticonceptivos/tendencias , Emigrantes e Inmigrantes/estadística & datos numéricos , Salud Reproductiva/estadística & datos numéricos , Salud Reproductiva/normas , Salud Reproductiva/tendencias , Salud Pública/métodos , Características Culturales
14.
Clin Endocrinol (Oxf) ; 80(3): 452-8, 2014 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23889327

RESUMEN

OBJECTIVE: Iodine deficiency is associated with thyroid dysfunction and adverse pregnancy outcomes. The aim of our study was to investigate the status of iodine saturation in women after spontaneous abortion (SpA) residing in an iodine-sufficient area and to evaluate their subsequent reproductive health. DESIGN: Nonrandomized prospective follow-up study. PATIENTS AND METHODS: We compared urinary iodine concentration (UIC) in 171 women 2-8 weeks (median 4) after an early SpA with age-matched controls. Women with known thyroid diseases were excluded. We also analysed a relationship of UIC to serum thyroid-stimulating hormone, free thyroxine, antibodies against thyroid peroxidase and thyroid ultrasound. Afterwards, we followed the women for a median of 38 months (range 12-47). We used a multivariate regression analysis to assess the influence of iodine status and other thyroid biochemical and ultrasound parameters on their subsequent reproductive health. RESULTS: Women after SpA were almost twice as likely to suffer from mild iodine deficiency and had lower median UIC as compared to age-matched controls [rate 105/181 (58·0%) vs 57/181 (31·5%), P < 0·001, medians UIC 92·00 vs 117·80 mcg/l, P < 0·001]. UIC was not influenced by the use of iodine supplements in the previous pregnancy. We did not find any association neither between UIC and thyroid dysfunction and/or thyroid antibodies, nor between UIC and rates of subsequent successful pregnancies or obstetric complications. CONCLUSIONS: More than half of women after SpA residing in an iodine-sufficient area are suffering from mild iodine deficiency. However, it does not seem to have a negative impact on their subsequent reproductive health.


Asunto(s)
Aborto Espontáneo/epidemiología , Enfermedades Carenciales/epidemiología , Yodo/deficiencia , Aborto Espontáneo/etiología , Aborto Espontáneo/orina , Adulto , Estudios de Casos y Controles , República Checa/epidemiología , Enfermedades Carenciales/complicaciones , Femenino , Estudios de Seguimiento , Humanos , Yodo/provisión & distribución , Yodo/orina , Embarazo , Prevalencia , Salud Reproductiva/estadística & datos numéricos , Índice de Severidad de la Enfermedad
15.
Glob Health Sci Pract ; 2(4): 427-43, 2014 Dec 10.
Artículo en Inglés | MEDLINE | ID: mdl-25611477

RESUMEN

BACKGROUND: The Nigerian Urban Reproductive Health Initiative (NURHI), a 6-year comprehensive family planning program (2009-2015) in 4 cities, intentionally applies communication theories to all program elements, not just the demand generation ones, relying mainly on a theory called ideation-the concept that contraceptive use is influenced by people's beliefs, ideas, and feelings and that changing these ideational factors can change people's behavior. PROGRAM DESCRIPTION: The project used multiple communication channels to foster dialogue about family planning, increase social approval for it, and improve accurate knowledge about contraceptives. Mobile service delivery was started in the third year to improve access to clinical methods in slums. METHODS: Data from representative baseline (2010-11) and midterm (2012) surveys of women of reproductive age in the project cities were analyzed. We also used propensity score matching to create a statistically equivalent control group of women not exposed to project activities, and we examined service delivery data from NURHI-supported clinics (January 2011-May 2013) to determine the contribution of mobile services to total family planning services. RESULTS: Three years into the initiative, analysis of longitudinal data shows that use of modern contraceptives has increased in each city, varying from 2.3 to 15.5 percentage points, and that the observed increases were predicted by exposure to NURHI activities. Of note is that modern method use increased substantially among the poorest wealth quintiles in project cities, on average, by 8.4 percentage points. The more project activities women were exposed to, the greater their contraceptive use. For example, among women not using a modern method at baseline, contraceptive prevalence among those with no exposure by midterm was 19.1% vs. 43.4% among those with high exposure. Project exposure had a positive dose-response relationship with ideation, as did ideation and contraceptive use. By the end of the observation period, mobile services were contributing nearly 50% of total family planning services provided through NURHI-supported clinics. Propensity score matching found that the increase in contraceptive use in the 4 cities attributable to project exposure was 9.9 percentage points. Intention to use family planning in the next 12 months also increased by 7.5 to 10.2 percentage points across the 4 cities. CONCLUSION: Demand-led family planning programs, in which demand generation is the driving force behind the design rather than the conventional, service delivery-oriented approach, may be more suitable in places where expressed demand for contraceptives is low.


Asunto(s)
Conducta Anticonceptiva/psicología , Servicios de Planificación Familiar/organización & administración , Conocimientos, Actitudes y Práctica en Salud , Población Urbana/estadística & datos numéricos , Adulto , Comunicación , Conducta Anticonceptiva/estadística & datos numéricos , Servicios de Planificación Familiar/estadística & datos numéricos , Femenino , Humanos , Estudios Longitudinales , Persona de Mediana Edad , Unidades Móviles de Salud/estadística & datos numéricos , Programas Nacionales de Salud/organización & administración , Nigeria , Educación del Paciente como Asunto , Salud Reproductiva/estadística & datos numéricos , Adulto Joven
16.
Rev. esp. nutr. comunitaria ; 19(3): 172-179, sept. 2013. tab
Artículo en Español | IBECS | ID: ibc-132817

RESUMEN

El objetivo de la presente revisión es evaluar los efectos de la L-carnitina sobre la infertilidad masculina y como complemento nutricional para la mejora de la calidad espermática y de la fertilidad. Se ha realizado una extensa búsqueda de publicaciones científicas en las siguientes bases de datos electrónicas especializadas: PubMed central (PMC)-NBCI, Elsevier Journal, Scielo España, Scirus y Science Direct. La infertilidad representa un problema para el 15% de las parejas en edad reproductiva. Del total de infertilidad, aproximadamente el 50% se asocia a infertilidad masculina. La ingestión de L-carnitina puede mejorar la fertilidad masculina, aportando energía celular a los espermatozoides, facilitando la movilidad, mejorando su proceso de formación, la maduración, la formación de la membrana, y aumentando la calidad seminal, mientras ayuda en el metabolismo que sigue a la eyaculación. La mayoría de estudios sugieren que la suplementación con L-carnitina podría tener un carácter preventivo y terapéutico, actuando también como complemento a tratamientos de infertilidad, especialmente en pacientes afectados por la infertilidad masculina idiopática. No obstante, no todos los estudios son concluyentes o existen variaciones de resultados. Por lo tanto, se necesita la realización de investigaciones adicionales para poder estar seguros de la eficacia y la seguridad de la suplementación con L-carnitina en tratamientos para la infertilidad masculina, así como determinar la dosis para mejorar los parámetros seminales y los resultados de embarazo (AU)


The aim of this review is to evaluate the effects of L-carnitine on male infertility and as a nutritional supplement for improving sperm quality and fertility. There has been an extensive search of scientific publications in the following specialized electronic databases: PubMed Central (PMC)-NBCI, Elsevier Journal, Scielo Spain, Scirus and Science Direct. Infertility is a problem for 15% of couples in reproductive age. Approximately 50% of infertility is associated with male infertility. The ingestion of L-carnitine may improve male fertility, bringing energy to the sperm cell, facilitating mobility, improving their training process, maturation, membrane formation, and increasing semen quality, while helping the metabolism that follows ejaculation. Most studies suggest that supplementation with L-carnitine may be preventative and therapeutic, also acting as a complement to infertility treatments, especially in patients with idiopathic infertility. However, not all studies are conclusive and exists large variations within results. Therefore, further research is needed to test the efficacy and safety of L-carnitine supplementation in male infertility treatments and to determine the dose for sperm parameters and pregnancy outcomes improvements (AU)


Asunto(s)
Humanos , Masculino , Adulto , Carnitina/metabolismo , Carnitina/uso terapéutico , Infertilidad Masculina/dietoterapia , Espermatozoides/fisiología , Semen/fisiología , Intervalos de Confianza , Valores de Referencia , Ingesta Diaria Recomendada/tendencias , Antioxidantes/metabolismo , Antioxidantes/uso terapéutico , Fenómenos Fisiológicos Reproductivos , Salud Reproductiva/estadística & datos numéricos , Salud Reproductiva/tendencias , Clomifeno/uso terapéutico
17.
Sex Transm Dis ; 40(3): 258-63, 2013 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23407471

RESUMEN

BACKGROUND: Current data on sexual health in the United States is limited, in part, because of a lack of measurement tools. It is difficult for programs to develop a holistic approach to improving sexual health that is data-driven and evaluable without a tool that encompasses sexual health beyond the absence of disease. The objective of this study was to understand possible factors associated with sexual health and reported differences in sexual health among women. METHODS: We conducted a survey measuring sexual health among women seeking care at the municipal sexually transmitted disease (STD) clinic in San Francisco between January 25, 2010, and June 15, 2010. Records were matched on variables including basic demographics, reason for visit, symptoms at visit, history of an STD, and STD diagnosis at the visit. RESULTS: A total of 822 women completed the questionnaire during the study period. Women reporting no recent sexual activity reported feeling more insecure, angry, isolated, and limited because of health compared with women with recent sexual activity. However, few differences were seen among women based on symptoms and diagnosis at visit. DISCUSSION: Given the minimal differences based on symptoms and disease, this suggests that there are other factors that impact the quality of life and sexual health. Creating tools that can be used to measure sexual health is a necessary first step for programs to understand the sexual health of a community. More broad-based assessments of sexual health in a variety of populations will be critical to identifying points of intervention and progress toward success.


Asunto(s)
Aceptación de la Atención de Salud/estadística & datos numéricos , Salud Reproductiva/estadística & datos numéricos , Conducta Sexual/estadística & datos numéricos , Enfermedades de Transmisión Sexual/epidemiología , Salud de la Mujer/estadística & datos numéricos , Adolescente , Adulto , Femenino , Encuestas Epidemiológicas , Humanos , Prevalencia , Calidad de Vida , San Francisco/epidemiología , Conducta Sexual/psicología , Enfermedades de Transmisión Sexual/prevención & control , Enfermedades de Transmisión Sexual/psicología , Encuestas y Cuestionarios
18.
Int J STD AIDS ; 23(10): 742-7, 2012 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-23104750

RESUMEN

A national audit of practice performance against the key performance indicators in the British Association for Sexual Health and HIV (BASHH) and HIV Medical Foundation for AIDS Sexual Health Standards for the Management of Sexually Transmitted Infections (STIs) was conducted in 2011. Approximately 60% and 8% of level 3 and level 2 services, respectively, participated. Excluding partner notification performance, the five lowest areas of performance for level 3 clinics were the STI/HIV risk assessment, care pathways linking care in level 2 clinics to local level 3 services, HIV test offer to patients with concern about STIs, information governance and receipt of chlamydial test results by clinicians within seven working days (the worst area of performance). The five lowest areas of performance for level 2 clinics were participating in audit, having an audit plan for the management of STIs for 2009-2010, the STI/HIV risk assessment, HIV test offer to patients with concern about STIs and information governance. The results are discussed with regard to the importance of adoption of the standards by commissioners of services because of their relevance to other national quality assurance drivers, and the need for development of a national system of STI management quality assurance measurement and reporting.


Asunto(s)
Infecciones por VIH/terapia , Auditoría Médica , Salud Reproductiva/normas , Enfermedades de Transmisión Sexual/terapia , Instituciones de Atención Ambulatoria/normas , Instituciones de Atención Ambulatoria/estadística & datos numéricos , Competencia Clínica , Trazado de Contacto , Manejo de la Enfermedad , Fundaciones , Infecciones por VIH/prevención & control , Humanos , Programas Nacionales de Salud/normas , Programas Nacionales de Salud/estadística & datos numéricos , Calidad de la Atención de Salud/normas , Calidad de la Atención de Salud/estadística & datos numéricos , Salud Reproductiva/estadística & datos numéricos , Enfermedades de Transmisión Sexual/prevención & control , Reino Unido/epidemiología
19.
Environ Int ; 47: 73-9, 2012 Oct 15.
Artículo en Inglés | MEDLINE | ID: mdl-22771522

RESUMEN

BACKGROUND: Few studies have investigated reproductive health effects of contemporary agricultural pesticides in boys. OBJECTIVES: To determine the association between pesticide exposure and reproductive health of boys. METHODS: We conducted a cross-sectional study in rural South Africa of boys living on and off farms. The study included a questionnaire (demographics, general and reproductive health, phyto-estrogen intake, residential history, pesticide exposures, exposures during pregnancy); and a physical examination that included sexual maturity development ratings; testicular volume; height, weight, body mass index; and sex hormone concentrations. RESULTS: Among the 269 boys recruited into the study, 177 (65.8%) were categorized as farm (high pesticide exposures) and 98 (34.2%) as non-farm residents (lower pesticide exposures). Median ages of the two groups were 11.3 vs 12.0 years, respectively (p<0.05). After controlling for confounders that included socioeconomic status, farm boys were shorter (regression coefficient (RC)=-3.42 cm; 95% confidence interval (CI): -6.38 to -0.45 cm) and weighed less (RC=-2.26 kg; CI: -4.44 to -0.75 kg). The farm boys also had lower serum lutenizing hormone (RC=-0.28 IU/L; CI: -0.48 to -0.08 IU/L), but higher serum oestradiol (RC=8.07 pmol/L; CI: 2.34-13.81 pmol/L) and follicle stimulating hormone (RC=0.63 IU/L; CI: 0.19-1.08 U/L). CONCLUSIONS: Our study provides evidence that farm residence is associated with adverse growth and reproductive health of pubertal boys which may be due to environmental exposures to hormonally active contemporary agricultural pesticides.


Asunto(s)
Exposición a Riesgos Ambientales/estadística & datos numéricos , Contaminantes Ambientales/análisis , Plaguicidas/análisis , Salud Reproductiva/estadística & datos numéricos , Adolescente , Agricultura/estadística & datos numéricos , Niño , Preescolar , Estudios Transversales , Dieta/estadística & datos numéricos , Contaminación Ambiental/estadística & datos numéricos , Humanos , Masculino , Fitoestrógenos/metabolismo , Población Rural/estadística & datos numéricos , Sudáfrica , Adulto Joven
20.
Int J STD AIDS ; 23(4): 282-4, 2012 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-22581954

RESUMEN

This project reports results from a questionnaire survey of sexual practices, contraception use and pregnancy plans in HIV-positive women in Leicester, UK, in order to establish the need for a dedicated sexual and reproductive health (SRH) clinic. The majority (96%) of women were aware of the benefits of antiretroviral therapy (ART) in pregnancy and 39% were planning a future pregnancy. Most (74%) used condoms consistently but their use decreased with the addition of another contraceptive method. Condoms were mostly obtained from non-National Health Service (NHS) settings. Long-acting reversible contraception (LARC) use was higher in this group of women than the general population and mainly provided by family planning services. A dedicated SRH clinic was thought to be useful by 79% of women. Data also identified some limitations of the existing service and need to provide holistic and integrated care.


Asunto(s)
Infecciones por VIH/psicología , Conocimientos, Actitudes y Práctica en Salud , Salud Reproductiva/estadística & datos numéricos , Conducta Sexual/estadística & datos numéricos , Adolescente , Adulto , Servicios de Planificación Familiar/métodos , Femenino , Humanos , Persona de Mediana Edad , Embarazo , Reino Unido , Adulto Joven
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